@nikitagudimchuk.bsky.social
Studying cytoskeleton and mitosis, focused on tubulin and microtubules. Curious about bacterial division and Ftsz. Interested in computational modeling, all kinds of microscopy, experimental and theoretical biophysics, bio- and med- chemisty
Narozna et al @gorbskylab.bsky.social uncover a high-frequency, chromosome 12-specific mis-segregation error in iPSCs. Eroded 12p arms lead to bridging & micronucleation, enabling widespread trisomy 12. A slight growth advantage allows trisomic cells to persist & dominate rupress.org/jcb/article/...
13.08.2025 17:15 β π 9 π 5 π¬ 0 π 0
Happy to share our latest work on the structure and assembly of holocentric kinetochores! Huge thanks to Ines for a very fruitful collaboration, Claudio for all the support, and congratulations to Christine and all co-authors!
www.biorxiv.org/content/10.1...
New preprint from the lab - the first paper made (almost) entirely here @qmul.bsky.social
We report how human outer kinetochore complexes Ndc80 and Ska form cooperative oligomers, that together stabilise microtubule ends against shortening.
www.biorxiv.org/content/10.1...
Key results below: (1/7)
it never gets old...... #microtubule dynamics - the fireworks of EB comets #microscopy
09.11.2024 03:04 β π 80 π 14 π¬ 0 π 0Excited to share our latest work in @pnas.org! Combining simulations and cryo-ET, we reveal how microtubules decide between growth and shortening. doi.org/10.1073/pnas... @maksimkalutskii.bsky.social @vladimirvolkov.bsky.social @compbiophys.bsky.social @mpi-nat.bsky.social @qmul.ac.uk @dundee.ac.uk.
03.06.2025 09:07 β π 34 π 11 π¬ 0 π 3Check out our latest research now out @embojournal.org. Huge shout-out to our postdocs Susana Eibes and Bhagya Lakshmi and the rest of the team for their amazing work! 1/11
27.05.2025 18:16 β π 11 π 3 π¬ 4 π 0Great new method to assess the size and shape of biomolecules. Also, the figures are incredibly beautiful π€©
09.05.2025 09:39 β π 33 π 5 π¬ 1 π 0This time-lapse captures 17 hours of axonal growth from a chicken dorsal root ganglion explant, visualized through the actin cytoskeleton using live confocal imaging.
I just submitted this video to the Nikon Small World in Motion competition. Today is the last day to upload yours! π
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Alex Long, the last postdoc from my lab at Stanford, is starting her own lab, continuing her beautiful work on evolutionary cell biology using chytrid fungi as a model. Check it out! alonglab.org
28.03.2025 14:28 β π 26 π 11 π¬ 0 π 0
Unique opportunity to join the CytoMorpho Lab (in Paris β€οΈ) as a postdoc to work on the self-organization and polarization of reconstituted networks made of microtubules, motors and actin filaments in vitro. Experience required.
Please Repost π thanks !
It would only be appropriate to post about the #geometrynodes #microtubule here too. For a full introduction, I have prepared the world's least professional youtube video.
www.youtube.com/watch?v=AYUy...
In our new preprint: biorxiv.org/content/10.1... we find that the tilted stalk of the NDC80 complexβa crucial component of the kinetochoreβmay be responsible for its asymmetric grip on microtubules. This conclusion may also extend to other MAPs. #Microtubule #Biophysics #Kinetochore
01.03.2025 19:00 β π 5 π 1 π¬ 0 π 0
Attention structural biologists!!! #CYTOSKELETON has a #specialissue that we are putting together on the "Structures of #microtubule and microtubule-related proteins". Submission deadline is April 1, 2025. Submit today. It is #FREE to publish in CYTOSKELETON.
20.02.2025 16:47 β π 6 π 3 π¬ 0 π 0
