Hematopoietic loss of Y chromosome leads to immune inhibitory receptor up-regulation, impairing senescent cell clearance
www.science.org/doi/10.1126/...
06.08.2025 19:09 — 👍 7 🔁 3 💬 0 📌 0
🔬Un estudio del CSIC demuestra que el deterioro asociado a la edad de los linfocitos T CD4 debilita la barrera intestinal y favorece la inflamación crónica y el envejecimiento celular
💉 El trabajo también presenta una posible terapia
➡️ https://tinyurl.com/97ssrv74
04.08.2025 08:02 — 👍 14 🔁 5 💬 0 📌 1
@cbm-csic-uam.bsky.social
02.08.2025 13:27 — 👍 0 🔁 0 💬 0 📌 0
Manu got the cover on our lab latest publication. Congratulations @mmgomezheras.bsky.social . So much deserved!
02.08.2025 13:18 — 👍 4 🔁 2 💬 1 📌 0
Especially excited to share this research led by @mmgomezheras.bsky.social ! 🤩 We show that a competent CD4+ T cell compartment is key to fostering host-microbiota mutualism and maintaining intestinal barrier integrity, becoming crucial to prevent inflammaging www.science.org/doi/10.1126/...
01.08.2025 22:56 — 👍 3 🔁 1 💬 0 📌 0
The August issue of #Science #Immunology is out! This week: T peripheral helper cells expressing IGFL2 contribute to rheumatoid #arthritis; vagal TRPV1+ sensory #neurons protect against #influenza virus infection; & transfer of #Tregs alleviates #inflammaging in mice!
wwwscience.org/toc/sciimmun...
01.08.2025 20:21 — 👍 12 🔁 7 💬 2 📌 0
Neutrophils drive vascular occlusion, tumour necrosis and metastasis - Nature
Neutrophils actively induce tumour necrosis, driving vascular occlusion, pleomorphic necrosis and metastasis.
I’m happy to share our latest work on tumour necrosis! During my time in the @megeblad.bsky.social lab, we found that tumour necrosis is not a passive phenomenon secondary to tumour growth, but an active phenomenon driven by neutrophils and NETs! Thread below: (1/13)
www.nature.com/articles/s41...
17.07.2025 11:27 — 👍 61 🔁 25 💬 3 📌 1
Amazing talk on “New insights into the anatomy of ‘brainwashing’” by Jonathan Kipnis @jonykipnis.bsky.social from @washumedicinebsky.social at #CNIC today 🙇🏼♀️🙇🏼♀️👏🏻👏🏻👏🏻👏🏻
21.04.2025 13:33 — 👍 10 🔁 2 💬 1 📌 0
Ramón y Cajal Fellow @ VascularPathology lab at Fundación Jiménez Díaz. Passionate about #mitochondria #Marfan #aorta #aneurysm #metabolism #cardiovascular
Postdoc Researcher at CBMSO (Madrid). Cell Plasticity in Development and Cancer.
Group Leader @CSHL (@amor-lab.bsky.social).
Fascinated by cellular senescence.
Harnessing CAR T cells to understand and treat aging.
Full professor at ETH Zürich, Stem Cell Biology and Ageing lab, D-HEST, passionate about hematopoietic stem cells, leukemia, ageing, single-cell, high altitude trekking :)
Junior Group Leader at CIB-Margarita Salas.
Lipid regulation of immunometabolism
He/him 🧠🧫🔬 VLC➡️NYC➡️MAD
Tinyurl.com/4cjrppb3
Severo Ochoa Postdoctoral Fellow at @CBM-CSIC-UAM.bsky.social. #Epigenetics, #Metabolism, #Liver, #VascularCell. PhD, #OrgullosamenteUNAM.
Twitter: @harry_brennan
Translating the Science of Health & Longevity
USD Bio Professor, Drug Developer
📖 Longer content on LinkedIn:
linkedin.com/in/jon-brudvig-phd-9b1830134
📰Sign up for my monthly Substack newsletter, Translation:
jonbrudvig.substack.com
Studying the cancer-cardiovascular disease interplay, with a focus on how cancer reprograms the hematopoietic and immune systems, at the Francis Crick Institute in London
http://www.adroverlab.com
We are interested in everything related to neutrophils! focused on understanding the pathophysiology of neutrophil-driven vascular damage, the importance of neutrophil diversity, and its modulation by environmental factors.
University of Münster, Germany
Aging and cancer stem cell heterogeneity - ICREA research professor - Quantitative Stem Cell Dynamics lab
at IRB Barcelona 🇦🇷🇪🇺🇺🇸 fraticellilab.com
Translational Immunology Research Lab at University of Minnesota Duluth.
Spanish Society on Cell Senescence
Biologist. Scientist. Curious. Researcher in rare diseases, cancer, hematopoiesis, epigenetics and bioinformatics, at CBM (CSIC)
Scientist interested in genome integrity maintenance mechanisms and cancer
Nature Communications is an open access journal publishing high-quality research in all areas of the biological, physical, chemical, clinical, social, and Earth sciences.
www.nature.com/ncomms/
Nature Immunology publishes original research, reviews and commentary of the highest quality and significance in all areas of immunology.
Nature Metabolism publishes studies that advance our understanding of metabolic and homeostatic processes in physiology and disease.
https://www.nature.com/natmetab/
