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Jack Kucinski

@jackkucinski.bsky.social

Ph.D. Candidate at The Ohio State University and Nationwide Children’s Hospital

28 Followers  |  58 Following  |  4 Posts  |  Joined: 22.07.2025  |  1.5179

Latest posts by jackkucinski.bsky.social on Bluesky

Thank you!

23.07.2025 19:05 — 👍 0    🔁 0    💬 0    📌 0
Transforming the Approach to Cancer Epigenomic Studies – Pediatrics Nationwide

Last, but certainly not least, this was a fantastic team effort and I appreciate all the support throughout this work! pediatricsnationwide.org/2025/07/22/t.... @nchfordocs.bsky.social @nationwidekids.bsky.social

23.07.2025 15:17 — 👍 2    🔁 0    💬 0    📌 0
Highly quantitative measurement of differential protein-genome binding with PerCell chromatin sequencing Tallan et al. report a versatile approach for highly quantitative protein-genome binding, demonstrating applications for human and zebrafish cells. The proposed PerCell methodology and analysis strate...

Additionally, we developed a PerCell ChIP-seq approach for spike-in chromatin normalization and quantitative analysis with our collaborators in the Stanton Lab in @cp-cellrepmethods.bsky.social. www.cell.com/cell-reports...

23.07.2025 15:16 — 👍 2    🔁 0    💬 1    📌 0
Preview
Rhabdomyosarcoma fusion oncoprotein initially pioneers a neural signature in vivo Kucinski et al. use embryonic zebrafish modeling to understand initial chromatin regulatory mechanisms of fusion-driven pediatric rhabdomyosarcoma. They found that the PAX3::FOXO1 oncoprotein function...

I’m happy to share our published work in @cp-cellreports.bsky.social! With zebrafish modeling of rhabdomyosarcoma, we showed that PAX3::FOXO1 utilizes homeobox motif recognition to initially bind closed DNA and activate neural programs present in the human disease. www.cell.com/cell-reports...

23.07.2025 15:14 — 👍 16    🔁 2    💬 2    📌 2

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