Chengyuan Wu, MD, MSBmE

Back from my first @ismrm.bsky.social —great science, thoughtful conversations, and a chance to present our work on how MRE helps explain DBS electrode bending! Grateful to collaborate with teams at UDelaware and Villanova. Definitely not my last ISMRM. And it didn't hurt that it was in Honolulu.

Warmer weather means more of this! IMO spare ribs >>> than baby back ribs

Apple wood smoked spare ribs using the 2:1:0.5 method

Highlights from #AES2024 Temporal Lobe Club 🧠

Temporal lobe epilepsy surgery review: ATL = best seizure control; LITT = balanced risk; Neuromodulation = lower risk, modest outcomes.

🔗 Check out the suummary article here: www.ncbi.nlm.nih.gov/pmc/articles...

#Epilepsy #Neurosurgery

What the FDA will likely do is produce *something* - just not a vax that includes strains chosen based on the committee & WHO's reasoned input.

🔹️They'll throw darts at a board, & the vax won't be a good match (it's tough to get it right even *with* annual input), but folks will think "see,...

1/5

Deep Brain Stimulation Electrode Deviations are Associated... : Operative Neurosurgery tion, an estimated 3% to 8% of patients still require revision surgery to address suboptimal electrode placement. DBS electrode deviation may occur at mechanical tissue interfaces, with denser interna...

Intracranial electrode bending is underrecognized but not random—it correlates with brain stiffness interfaces. Our study shows MR elastography can predict deviations, challenging the idea that bending is inevitable.

🔗 Read the full article here: journals.lww.com/onsonline/ab...

#DBS #stereotaxy

NIH announces new funding policy that rattles medical researchers The National Institutes of Health has dramatically changed its grant-making terms by limiting how much it will disperse for costs such as equipment and administration.

NIH’s new policy capping indirect cost funding at 15% is a gut punch to academic research. Cutting support for lab upkeep & admin costs means fewer resources for scientists & slower progress. This could seriously hurt innovation...

www.npr.org/sections/sho....

How is it that Parkinson's name has been perpetuated in our language, but the man himself has been forgotten? What do you know about the man himself? Nadeem Toodayan and Andy Lees have written a brilliant new article sharing the details and the history not only of the memorial, but of the man.

🚨 Upcoming ASSFN Webinar: How to Optimize DBS Targeting 🚨

Join us tomorrow for the first DBS Targeting webinar, where experts will share insights on optimizing deep brain stimulation (DBS) targeting to improve patient outcomes.

Register now: zoom.us/meeting/regi...

U.S. Surgeon General Calls for Cancer Warnings on Alcohol Dr. Vivek Murthy’s report cites studies linking alcoholic beverages to at least seven malignancies, including breast cancer. But to add warning labels, Congress would have to act.

"... alcohol directly contributes to 100,000 cancer cases and 20,000 related deaths each year...[but] fewer than half of Americans identified alcohol use as a risk factor for cancer"

www.nytimes.com/2025/01/03/h...

This is what happens when a surgeon puts together a 'bouquet garni'...😬

Huge prime rib for Christmas dinner🎄🤤

Dry brined overnight, injected with garlic, rosemary, & thyme infused wagyu tallow. Smoked for 4 hours with a rosemary, sage, & thyme 'bouquet garni' tossed in every hour. Finally seared to develop a nice crust before a long rest.

Happy holidays everybody!!!

I keep updating the DBS starter pack – and super happy we have already 109 folks on here!

Am I missing somebody?

go.bsky.app/B9A9Cho

😳

Fact: #DeepBrainStimulation can't improve every Parkinson's symptom. Here's some info on what DBS can and can't help.

👉 Discover more expert info in our interview: https://t.co/enDba26zhm

#DemystifyingDBS
In partnership with @AbbottNews, @bostonsci and @Medtronic #parkinson #parkinsons

Telomere Length and Biological Aging: The Role of Strength Training in 4814 US Men and Women Telomere length is an index of cellular aging. Healthy lifestyles are associated with reduced oxidative stress and longer telomeres, whereas unhealthy behaviors are related to shorter telomeres and gr...

"...for each 10 min increase in time engaged in strength training per week, the mean telomere length was about 6.7 base pairs longer, on average, compared with non-lifters...equivalent to almost 4 years less biological aging for adults participating in about 90 min of strength training per week."

A key part of researching #DeepBrainStimulation for Parkinson's is finding out the benefits. Here are 5️⃣ examples from DBS experts.

👉 Discover lots more expert info in our interview: https://buff.ly/3MMrS8M

🧵 1/7

#DemystifyingDBS
In partnership with @AbbottNews, @bostonsci and @Medtronic

YouTube video by Dr. Glaucomflecken My Thoughts On The United Healthcare CEO Murder

youtube.com/shorts/VGgQD...

Very cool demonstration of what Renishaw does with robotics outside of #Neurosurgery at #AES2024

Our very own Michael Sperling on the big stage at #AES2024 for the Annual Course

Resident attendees

Course faculty

Another year in the books for the AES-ASSFN joint course on #Epilepsy Surgery for #Neurology & #Neurosurgery residents

Many thanks to all the amazing faculty who have dedicated their time and effort to education! And thank you to all the residents who made the trip out to #AES2024!

Neena Marupudi from the University of Michigan continues to push the boundaries of minimally invasive disconnection surgery for #epilepsy with endoscopic approaches

#AES2024

A simply fantastic presentation by Marc Guenot from the University Hospital of Lyon about thermo-SEEG!

Approximately 30% seizure free at 2 months & 10% at 1 year.

But greater utility may be diagnostic value: 92% PPV & 45% NPV of outcome after resection if >2 months of seizure freedom after RF

Great summary of #LITT for mesial temporal lobe #epilepsy by Brett Youngerman @columbiauniversity.bsky.social!

TLDR: Long term outcomes ~50% seizure freedom rate with early experience. But we have learned much about how to perform the procedure & will likely see improved outcomes in years to come.

“The biggest impact of LITT has been on the treatment of hypothalamic hamartomas.”

Dan Curry from Texas Children’s recaps the last 10 years of laser ablation in the treatment of Pediatric Epilepsy

#AES2024

Excited for the #neurosurgery symposium at #AES2024!

My Co-Director Dr. Andrew Zillgitt kicks things off for the #AES-#ASSFN joint #Epilepsy Surgical Course at the American Epilepsy Society #AES2024 annual meeting in #LA

Just about 1 week until #AES2024 in #LA!

Hi everyone!

Moving here to @bsky.app over from #X #Twitter!