Trishna Das @trishnadas - Bluesky Profile

A new @nature.com Reviews Drug Discovery article highlights the first candidate drug to combat #cachexia — a major step toward treating cachexia, a devastating condition affecting many people with cancer.

🔗 Read the full article: www.nature.com/articles/d41...

#CancerResearch

22.10.2025 09:01 — 👍 3 🔁 3 💬 0 📌 0

GIPR agonism and antagonism decrease body weight and food intake via different mechanisms in male mice Nature Metabolism, Published online: 29 April 2025; doi:10.1038/s42255-025-01294-xThis study, together with a companion manuscript, show that, in mice, weight loss as a result of GIP receptor antagonism requires, and potentiates, functional GLP-1 receptor signalling in the brain, explaining how both GIP receptor agonists and antagonists trigger weight loss through different mechanisms.

29.04.2025 13:56 — 👍 3 🔁 1 💬 0 📌 1

If you swung by our Molecular Biosciences trivia booth, hope you enjoyed the trivia and the stickers are now proudly displayed — happy Rutgers Day! @sayoni.bsky.social

26.04.2025 21:15 — 👍 1 🔁 1 💬 0 📌 0

New @science.org
Discovery of a mechanism for cancer cachexia (components of severe apathy, depression) explained by a neuroimmune circuit
www.science.org/doi/10.1126/...
www.science.org/doi/10.1126/...

10.04.2025 18:21 — 👍 174 🔁 45 💬 6 📌 3

YouTube video by Ludwig Cancer Research Eileen White, Ludwig Princeton Associate Director

Ludwig Princeton Associate Director Eileen White discusses the importance of the clinical component connection of Ludwig’s mission to advance the prevention and control of cancer.

#CancerResearch #CanSky #OncoSky

youtu.be/L5xLxO7qAAI

04.03.2025 20:27 — 👍 1 🔁 1 💬 0 📌 0

An organism-level quantitative flux model of energy metabolism in mice Mammalian tissues feed on nutrients in the blood circulation. At the organism level, mammalian energy metabolism is comprised of the oxidation, storag…

Happy to share the final version of this work where we incorporated isotope labeled CO2 data into mass spectrometry based flux analysis, resulting in a flux model that depicts at the whole-body level functioning of energy metabolism in health and disease.
www.sciencedirect.com/science/arti...

20.02.2025 17:31 — 👍 34 🔁 16 💬 1 📌 0

Congratulations to @rutgerscancer.bsky.social & @rwjbarnabashealth.bsky.social's Dr. Eileen White on being the keynote speaker at the European Association for Cancer Research (EACR) #EACR2025 Congress!

17.02.2025 17:39 — 👍 4 🔁 1 💬 0 📌 0

Translocation renal cell carcinoma says no to the Warburg effect Nature Metabolism, Published online: 06 February 2025; doi:10.1038/s42255-025-01216-xA new study reveals that in drastic contrast to other cancer types, translocation renal cell carcinoma (tRCC) is transcriptionally rewired towards an oxidative…

06.02.2025 13:01 — 👍 4 🔁 2 💬 0 📌 0

Implantation of engineered adipocytes suppresses tumor progression in cancer models - Nature Biotechnology Adipose manipulation transplantation can reduce tumor growth and proliferation in vitro and in mouse models.

Tumors need a lot of nutrients to grow. By engineering and implanting fat cells to outcompete cancers for nutrients we can suppress them. Novel cancer therapy called Adipose Manipulation Transplantation (AMT). AMAZING work led by and dedicated to Hai Nguyen.
www.nature.com/articles/s41...

04.02.2025 15:49 — 👍 28 🔁 7 💬 2 📌 3

Myostatin's flex on the reproductive hormone axis A muscle hormone controls the mammalian reproductive system

A new Science study in mice identifies cross-talk between muscle and the reproductive system and raises questions about interventions to increase muscle mass that might affect fertility.

Learn more in a new #SciencePerspective:

24.01.2025 19:56 — 👍 66 🔁 16 💬 1 📌 1

Snow turns College Ave into a winter wonderland ❄️ @rutgersuniversity.bsky.social #Rutgers

20.01.2025 02:38 — 👍 6 🔁 0 💬 0 📌 0

Trishna Das

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