Boston Protein Design and Modeling Club

quick reminder to join us tonight at @harvardmed.bsky.social for a great talk by Colby Ford @colby.tuple.xyz

schedule introduction and membership Boston Protein Design and Modeling Club (BPDMC) is a community of computational protein engineers and modelers from both academia and industry. While we are based in Boston...

Come learn about how to run the computational infrastructure that's powering the protein design revolution

July 9th 2025 at 7pm EDT in TMEC250 @harvardmed.bsky.social

"Model. Package. Deploy. Repeat: A DevOps Approach to Biomolecular Scalability"

Colby Ford @colby.tuple.xyz

bpdmc.org

YouTube video by Boston Protein Design and Modeling Club RNA Function, Design, and Modeling

Don't fret if you missed Silvi Rouskin's brilliant and engaging talk on #RNA structure last night - you can check out the recording 👇
youtu.be/oS_Cb-YMymw

schedule introduction and membership Boston Protein Design and Modeling Club (BPDMC) is a community of computational protein engineers and modelers from both academia and industry. While we are based in Boston...

Protein isn't the only amazing macromolecule that folds into 3D shapes - come see Silvi Rouskin in Room 181, Building 68 at MIT on Wednesday, June 11th at 7pm EDT to learn more about #RNA structure design and modeling!

"RNA Function, Design, and Modeling"

bpdmc.org

YouTube video by Boston Protein Design and Modeling Club Designing new and improved functions in natural protein folds

If you missed out on Sarel Fleishman's extraordinary talk last night, have no fear - you can check out the recording 👇
youtu.be/2aaWh8yVq8U

quick reminder to come join us tonight at 7pm EDT to see Sarel Fleishman!

and please note the change in date!

schedule introduction and membership Boston Protein Design and Modeling Club (BPDMC) is a community of computational protein engineers and modelers from both academia and industry. While we are based in Boston...

Our speaker next week is an amazing scientist from out of town, and this is one that you won't want to miss!

Thursday, May 15th, 7pm EDT
Cannon Room, Building C, @harvardmed.bsky.social

Sarel Fleishman
www.fleishmanlab.org

"Designing new and improved functions in natural protein folds"

bpdmc.org

YouTube video by Boston Protein Design and Modeling Club Design of small molecule binding proteins using deep learning

in case you missed the superb seminar that Ben Fry gave back in January, you can now check out the recording youtu.be/IgFgAYQrke4
and the preprint www.biorxiv.org/content/10.1...

Zero-shot design of drug-binding proteins via neural selection-expansion Computational design of molecular recognition remains challenging despite advances in deep learning. The design of proteins that bind to small molecules has been particularly difficult because it requ...

Super excited to share a new preprint from our lab on design of small-molecule binding proteins using neural networks! The paper has a bit of everything. A new graph neural network, new design algorithms, and experimental validation. www.biorxiv.org/content/10.1...
🧵🧪

YouTube video by Boston Protein Design and Modeling Club Interpreting state-of-the-art structure predictors for protein-peptide complexes

If you missed @lindseyguan.bsky.social's outstanding talk last week, you can check out the recording 👇
youtu.be/R87pmoB3QF0

schedule introduction and membership Boston Protein Design and Modeling Club (BPDMC) is a community of computational protein engineers and modelers from both academia and industry. While we are based in Boston...

Yes, there is a live stream option, and we share the zoom link with BPDMC members. You can find instructions for how to sign up at bpdmc.org

schedule introduction and membership Boston Protein Design and Modeling Club (BPDMC) is a community of computational protein engineers and modelers from both academia and industry. While we are based in Boston...

We're so excited - our upcoming seminar will be by Lindsey Guan on Wednesday, April 9th 2025 starting at 7pm EDT in Room 181, Building 68, MIT @mitofficial.bsky.social

"Interpreting state-of-the-art structure predictors for protein-peptide complexes"

bpdmc.org

YouTube video by Boston Protein Design and Modeling Club From DNA Origami to Protein Design: Symmetry-Guided Principles Across Scales

if you missed seeing Seth Fraden's great seminar last night, have no fear - you can check out the recording: youtu.be/zyJmWLzkh7Q

quick reminder - don't miss out on an awesome seminar by Seth Fraden tonight!

YouTube video by Boston Protein Design and Modeling Club Boltz-1 and the Future of Biomolecular Foundation Models

@bpdmc.bsky.social hosts those on the bleeding edge of molecular modeling. if you want to know what's what, check out their YouTube page. here's the latest presentation:

schedule introduction and membership Boston Protein Design and Modeling Club (BPDMC) is a community of computational protein engineers and modelers from both academia and industry. While we are based in Boston...

As usual, we've got another exciting seminar coming up!

Come see Seth Fraden on Wednesday, March 12th 2025 at 7pm EDT in the Cannon Room, Building C, Harvard Medical School

"From DNA Origami to Protein Design: Symmetry-Guided Principles Across Scales"

bpdmc.org

YouTube video by Boston Protein Design and Modeling Club Boltz-1 and the Future of Biomolecular Foundation Models

for the folks who missed seeing @gcorso.bsky.social and @jeremywohlwend.bsky.social give their awesome seminar live the other week, you can check out the recording 👇
youtu.be/K-gzTJMy1ag

We've got an exciting seminar by @gcorso.bsky.social and @jeremywohlwend.bsky.social coming up this Wednesday, February 12th starting at 7pm EST in Room 181, Building 68, MIT

"Towards a Unified Approach for Biomolecular Interaction Modeling: Boltz-1 and the Future of Biomolecular Foundation Models"

quick reminder to come join us in the Cannon Room tonight (which is not yet under construction) to see a great seminar by Ben Fry!

schedule introduction and membership Boston Protein Design and Modeling Club (BPDMC) is a community of computational protein engineers and modelers from both academia and industry. While we are based in Boston...

We can't wait for Ben Fry to kick off our 2025 seminar series next week. Come join us on Wednesday, January 15th at 7pm EST in the Cannon Room, @harvardmed.bsky.social

"Design of small molecule binding proteins using deep learning"

bpdmc.org

YouTube video by Boston Protein Design and Modeling Club Physics-aware agentic artificial intelligence to model, design and discover proteins

A holiday break is the perfect time to watch the awesome talk that @profbuehlermit.bsky.social gave back in October

Happy holidays everyone!

youtu.be/xZYI8cxW-3c

YouTube video by Boston Protein Design and Modeling Club De novo design of miniprotein-based natural killer cell engagers

for the folks who weren't able to join for the brilliant presentation by Mireia Solà Colom last week to cap off our 2024 seminar series, you can check out the recording 👇
youtu.be/e6oZgGWjD_0

See you tonight at @harvardmed.bsky.social for an amazing seminar by Mireia to cap off 2024!

*Please note the change of location*

Now you can easily follow all of the amazing scientists that have presented at Boston Protein Design and Modeling Club

go.bsky.app/53tEUeR

Quick update! we need to change the venue - we will be meeting in the Cannon Room, Building C, @harvardmed.bsky.social

apologies for any confusion!

Quick update! we need to change the venue - we will be meeting in the Cannon Room, Building C, @harvardmed.bsky.social

apologies for any confusion!

schedule introduction and membership Boston Protein Design and Modeling Club (BPDMC) is a community of computational protein engineers and modelers from both academia and industry. While we are based in Boston...

There's just one meeting left in 2024, and we have a spectacular seminar by Mireia Solà Colom lined up for you! Join us at 7pm in Room 181, Building 68, MIT on Wednesday, December 11th.

"De novo design of miniprotein-based natural killer cell engagers"

See you there & Happy Thanksgiving!
bpdmc.org

YouTube video by Boston Protein Design and Modeling Club Massively parallel discovery of peptides to inhibit cellular protein interactions

for the folks who missed Andrew Savinov's fantastic seminar this week, you can check out the recording 👇
youtu.be/s31yC7nQqDs
and thanks again to Pillar VC for hosting!