MibiNet

We Are very happy that our Paper was published. Thank to everyone involved

pubs.acs.org/doi/10.1021/...

@mibinet.bsky.social @mfeldbruegge.bsky.social @frunzkelab.bsky.social

Elucidating the itaconic acid pathway dynamics in Saccharomyces cerevisiae Itaconic acid, a versatile platform chemical, has garnered significant attention due to its broad use in polymers, resins, and bio-based materials. Al…

New MibiNet paper published! Engineered yeast for itaconate synthesis. Investigated transport between mitochondria, cytosol, and environment. Details here!
www.sciencedirect.com/science/arti...
#MibiNet #Yeast #MetabolicEngineering

Huge thanks to Prof. Dr. Nick Talbot! We were fascinated by his MibiNet talk, exploring how the appressorium uses turgor pressure to infect rice & how the transpressorium spreads the fungus. Brilliant insights!
@talbotlabtsl.bsky.social
#MibiNet

FEBS Press The urgent need for sustainable agriculture places biological nitrogen fixation at the forefront of current biotechnological research. Plant growth-promoting rhizobacteria play crucial roles in agric...

A small contribution from us & Edi Gerhardt @febsj.bsky.social

Highlighting the recent findings: Structure of the NifL-NifA complex controlling nitrogen fixation gene expression in Azotobacter

febs.onlinelibrary.wiley.com/doi/10.1111/...
@sfb1381.bsky.social @hhu.de @mibinet.bsky.social

In Vivo Online Monitoring of Intracellular Lipid Accumulation in Ustilago maydis Single cell oils produced in microorganisms constitute appealing alternatives to plant oils. Oleaginous fungi accumulate triacylglycerols in lipid droplets (LD). Their biosynthesis is typically indu...

MibiNet & @ceplas.bsky.social Data Management Team supported this new publication in making its raw data FAIR and accessible in the DataHUB🎉. This is how transparent research is done!
analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/...
#FAIRdata #OpenScience #DataHUB #DataPLANT

This is a great opportunity to work with a fantastic supervisor in a great research environmenment on a super-interesting question 👇

Diurnal rhythm causes metabolic crises in the cyanobacterial mutants of c-di-AMP signaling cascade Biological sciences; Biochemistry; Microbiology; PII-like protein SbtB; c-di-AMP signaling; Cyanobacteria; Carbon/Nitrogen metabolism; Redox imbalance; Photosynthesis; Reactive oxygen species (ROS); C...

A bit late 🙃 but happy to share our recent findings on #cdiAMP signaling in controlling #cyanobacteria #diurnal rhythm in @cp-iscience.bsky.social

www.cell.com/iscience/ful...

#cdiAMP is involved in almost all cellular processes, explaining it's essentiality in #cyano
@hhu.de
@mibinet.bsky.social

Please RT:
We have an opening for a junior group leader position in „Phage Biology & Biotechnology“.
www.fz-juelich.de/de/karriere/...

Interested candidates are encouraged to contact me via email for further details.

@spp2330.bsky.social; @mibinet.bsky.social

Long-term homeostasis in microbial consortia via auxotrophic cross-feeding - Nature Communications Synthetic microbial consortia are collections of strains which can segregate metabolic tasks for efficient use in biomaterials, biomanufacturing, and biotherapeutics. Here, the authors present a method to maintain and tune the ratio of two co-cultured bacterial strains via growth medium manipulation.

Very interesting work for maintaining synthetic microbial consortia

www.nature.com/articles/s41...

@mibinet.bsky.social

Excited to share our latest work, spearheaded by @gabmrojas.bsky.social!

GPCRs are central sensors in eukaryotes, but little is known about them in fungi. In Ustilago maydis, we now uncovered a host-dependent GPCR mechanism that promotes fungal infection.

Gabriel nicely explains the full story👇

New Insights Into Bacterial Motility and DNA Transfer:
a small press on our discovery of ComFB signaling family by @claussenarne.bsky.social @hhu.de

www.eurekalert.org/news-release...
w/ @mygalperin.bsky.social @thethormannden.bsky.social
@cmfi.bsky.social @mibinet.bsky.social @sfb1381.bsky.social

It was a great pleasure hosting Prof. Edileusa Marques Gerhardt from Universidade Federal do Paraná, Brazil for our regular @mibinet.bsky.social seminar series @hhu.de

She told us about the recent updates in #PII #Signaling in bacteria 🦠 .... What a beautiful system ;-)

We discovered a new family of c-di-NMP receptors, widespread in bacteria & regulating🦠motility @pnas.org

A great collab. w/ @mygalperin.bsky.social @vikramalva.bsky.social @thethormannden.bsky.social

www.pnas.org/doi/10.1073/...

@hhu.de @cmfi.bsky.social
@sfb1381.bsky.social
@mibinet.bsky.social

Genetic integration is not required for establishing permanent endosymbiotic compartments

www.pnas.org/doi/10.1073/...

Could be interesting for @mibinet.bsky.social

From @diamondlab.bsky.social
Stable #cyanobacteria communities w/ heterotrophs. An important development for folks working on cyanobacteria, microbial community formation and establishment in lab settings

Could be interesting for @mibinet.bsky.social

academic.oup.com/ismej/advanc...

Very interesting!
@mibinet.bsky.social

www.cell.com/trends/genet...

The second messenger c-di-AMP controls natural competence via ComFB signaling protein Cell Discovery - The second messenger c-di-AMP controls natural competence via ComFB signaling protein

Happy to share our latest finding @natureportfolio.nature.com on #cdiAMP signaling roles in #cyanobacteria natural competence via #ComFB (a new family of #cdiNMP receptors)
@hhu.de @cmfi.bsky.social @biologyunifreiburg.bsky.social
Fund @dfg.de @sfb1381.bsky.social
@mibinet.bsky.social
rdcu.be/eyLXT

Cellular organelles interact with each other 🤩 .... Very interesting ;-)

ROS transfer at peroxisome-mitochondria contact regulates mitochondrial redox
@mibinet.bsky.social

www.science.org/doi/10.1126/...

HHU Research Day on 5.7.2025 was a great success! MibiNet captivated visitors with the "Sweet Secrets – Why Even Fungi Have a Sweet Tooth" experiment. We showed how sugar is broken down in microorganisms – from yeast to the corn smut fungus U. maydis. Big thanks to the team on site!
#MibiNet #HHU

Microbe with bizarrely tiny genome may be evolving into a virus With DNA focused almost entirely on replication, newly discovered organism blurs the line between cells and viruses

Very interesting read...

Microbe with bizarrely tiny genome may be evolving into a virus #symbiosis @mibinet.bsky.social

www.science.org/content/arti...

T7 RNA polymerase-based gene expression from a transcriptionally silent rDNA spacer in the endosymbiont-harboring trypanosomatid Angomonas deanei Eukaryotic life has been shaped fundamentally by the integration of bacterial endosymbionts. The trypanosomatid Angomonas deanei that contains a β-proteobacterial endosymbiont, represents an emerging ...

New paper alert: Kröninger et al. (2025) on gene expression in Angomonas deanei in PLoS One! For this paper, an ARC was developed with the support of DataPLANT & CEPLAS. #DataManagement @evanowack.bsky.social @nfdi4plants.bsky.social @ceplas.bsky.social
journals.plos.org/plosone/arti...

Join us for HHU Düsseldorf Research Day on July 5th! 🔬 Explore diverse research, enjoy presentations, hands-on experiments, lab tours, and delicious food. See science in action. #ResearchDayHHU @hhu.de

Together with @ceplas.bsky.social we are planing a panel discussion in German about the applications of plant research in withstanding climate change at the "Haus der Universität" in Düsseldorf. Students, citizen scientists and all interested people are welcome to attend!

I feel we just scratched the surface of 🌱 #immunity response to #phage #biocontrol against pathogens🦠.
doi.org/10.1101/2025...

But this is such a cool team to work with👇 and I am looking forward to do more. 🧪 #PlantScience #PlantResearch #microbiology #PMI #PlanMicrobeInteractions

Native metabolomics identifies pteridines as CutA ligands and modulators of copper binding CutA, a conserved protein across all domains of life, has long been linked to copper tolerance in Escherichia coli , though recent studies question this association. To clarify its function, we studie...

We cracked the mystery: Pteridines are the natural ligands of CutA, a widespread protein in nature
@hhu.de @cmfi.bsky.social

I started this project 8y ago. We showed that it's of PII signaling family, but it's function remained unknown coz we didn't know what it bind
www.biorxiv.org/content/10.1...

Successful Girls' Day at HHU, powered by the Institute of Microbiology & MibiNet! Explored "Fungi as a chemical factory" with enthusiastic young minds. Great questions & future scientists in the making! Hope to see them back at uni someday.🔬👧 #GirlsDay2025 #MibiNet
@hhu.de @mfeldbruegge.bsky.social

SFB 1535 @mibinet.bsky.social goes @vaam-microbes.bsky.social

Thanks to @franznarberhaus.bsky.social, Julia Bandow and @dirktischler.bsky.social for the organisation of a fantastic meeting.
We are #Vaamily 🥳

I'm super happy that our story is now published!
📖 www.science.org/doi/10.1126/...
But what changed compared to the original preprint?

Also, I feel i should post Movie 1 🎥, that inspired the cover. Back when I did the original bluesky thread, movies were not available.

Crop root bacterial and viral genomes reveal unexplored species and microbiome patterns Comprehensive bacterial and viral genome collections from crop roots uncover a large number of unexplored species and highlight conserved patterns within root microbiomes. Genomes and isolates are acc...

#midweekmicro🔬

🌱Crop root bacterial and viral genomes reveal unexplored species and microbiome patterns

@cellpress.bsky.social #microsky #resource

www.cell.com/cell/fulltex...

Angomonas deanei with flourescent-labeled nucleus and endosymbiont. ETP9 localizes at the endosymbiont division site.

Out today: Exciting intermediate between endosymbiont and organelle identified! Endosymbionts in Angomonas deanei lost nearly all bacterial cell division genes. Instead, we identified a host-encoded protein, ETP9, that became specialized for endosymbiont division. 1/2
www.science.org/doi/10.1126/...