Natasha Golovchenko

Congrats Ananya!!! So proud 💚

19.05.2025 23:13 — 👍 2    🔁 0    💬 1    📌 0

Thanks to @edelblumlab.bsky.social for being a wonderful mentor and to @saraalonsomera.bsky.social for being the best partner in crime since the very beginning! 🎓🔬🎉

15.05.2025 01:08 — 👍 6    🔁 0    💬 0    📌 0

Microbiota promote enhanced CD39 expression in γδ intraepithelial lymphocytes through the activation of TCR and IL-15 signaling Intraepithelial lymphocytes expressing the γδ T cell receptor (γδ IEL) provide continuous surveillance of the intestinal epithelium. We report that mice harboring a microbiota-specific hyperproliferat...

If you read our #ScienceImmunology paper and want to know how the #microbiota induces #CD39 to promote a #gdTcell #immunoregulatory phenotype, check out our new #preprint!

25.03.2025 20:15 — 👍 7    🔁 4    💬 0    📌 0

two men are riding a bicycle with a basket on it . ALT: two men are riding a bicycle with a basket on it .

#Bluetorial: In our latest paper on #gdTcells and #IBD in #ScienceImmunology we found that γδ IEL number and regulatory function are severely compromised BEFORE ileal inflammation occurs, suggesting that γδ IELs may maintain IEL homeostasis in response to a pro-inflammatory microenvironment. 1/n

22.03.2025 20:04 — 👍 42    🔁 16    💬 4    📌 2

Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis Multiple layers of γδ IEL dysregulation and loss of their immunosuppressive capacity occur before the onset of chronic ileitis.

📚NEW #gdTcell PAPER ALERT! Dysregulation of γδ intraepithelial lymphocytes precedes Crohn’s disease–like ileitis | Science Immunology
Bluetorial coming soon!!! #gastrosky #GIsky #IBDsky @nbgolovchenko.bsky.social @squeakyanimal.bsky.social @andrewfong.bsky.social

21.03.2025 18:14 — 👍 69    🔁 28    💬 10    📌 1

Congratulations to Dr. Sara Alonso on a spectacular defense! 👏 🍾 Sara is a powerhouse of #gdTcell #immunometabolism data in the lab. We can’t wait to share the #preprint of her thesis work on #gdTcells and #microbiota with you later this week. @sinaiimmuno.bsky.social

18.03.2025 22:06 — 👍 17    🔁 6    💬 0    📌 0