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Pawel Grzechnik

@grzechnikpawel.bsky.social

Group Leader and Lecturer, Division of Molecular and Cellular Function, FBMH, University of Manchester Transcription, ncRNAs and rare genetic diseases | Loves all types of martial arts www.grzechniklab.com

510 Followers  |  251 Following  |  19 Posts  |  Joined: 06.12.2023  |  2.1197

Latest posts by grzechnikpawel.bsky.social on Bluesky

Lecturer / Senior Lecturer in Structural Biology:Oxford Road The purpose of this post is to undertake high quality research and also excellent teaching. Hence, the ability to enhance teaching activities within our UG/PG programmes will also be expected.

Structural biologists!
Our division has an opening for a Lecturer/Senior Lecturerโ€”apply now!

www.jobs.manchester.ac.uk/Job/JobDetai...

15.11.2025 15:44 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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The University of Manchester, Division of Molecular and Cellular Function PhD Projects, Programmes & Scholarships - 21 PhDs Listed FindAPhD. Search Funded PhD Projects, Programmes & Scholarships at The University of Manchester, Division of Molecular and Cellular Function.

21 fully funded PhD projects are available in our division!

www.findaphd.com/phds/divisio...

11.10.2025 09:21 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Graham Pavitt

We are excited to announce that Professor Graham Pavitt, Chair in Molecular Biology, has been appointed as our new Head of Division!
Join us in welcoming Graham to his new roleโ€”we look forward to the exciting times ahead!

research.manchester.ac.uk/en/persons/g...

17.07.2025 08:10 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Bicentenary Early Career Research Fellowships | Biology, Medicine and Health | University of Manchester Find out about and apply for a Bicentenary Early Career Research Fellowship.

Early-career fellowships at the University of Manchester!

To celebrate 200 years of The University of Manchester, the Faculty of Biology Medicine and Health offers a 3-year Postdoctoral Fellowship to support exceptional early-career researchers:

www.bmh.manchester.ac.uk/research/sup...

04.03.2025 21:21 โ€” ๐Ÿ‘ 4    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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Research Opportunities - Cancer Research UK Manchester Centre Explore the range of postgraduate cancer research opportunities available in Manchester.

Exciting PhD opportunity available in my lab for the students from Black heritage background. Apply soon. ๐Ÿคž๐Ÿคž๐Ÿคž
@mcr-breastcentre.bsky.social @mcf-uom.bsky.social

CRUK Black Leaders in Cancer Non-Clinical PhD Opportunity

๐Ÿ“… Deadline: 4 April

๐Ÿ”— crukcentre.manchester.ac.uk/study/resear...

04.03.2025 20:18 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Subtype-specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers Gene expression is tightly controlled by DNA elements called enhancers by associating with lineage-specific transcription factors. These enhancers transcribe non-coding RNAs (called enhancer RNAs or e...

Our lab's very first manuscript is out in BioRxiv. Hope this would be interesting for breast cancer scientists: www.biorxiv.org/content/10.1... @mcf-uom.bsky.social @mcr-breastcentre.bsky.social @mcrcnews.bsky.social @official-uom.bsky.social @fbmh-uom.bsky.social

04.03.2025 20:20 โ€” ๐Ÿ‘ 4    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

A fantastic postdoc opportunity available for talented PhD graduates to work in our CRUK funded PhD project.
jobs.manchester.ac.uk/internal/Job...
@mcr-breastcentre.bsky.social @mcrcnews.bsky.social @mcf-uom.bsky.social @mcrcellmatrix.bsky.social @official-uom.bsky.social @fbmh-uom.bsky.social

04.03.2025 20:14 โ€” ๐Ÿ‘ 7    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Which side are you on?

28.02.2025 22:57 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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UNITED24 - The initiative of the President of Ukraine UNITED24 was launched by the President of Ukraine Volodymyr Zelenskyy as the main venue for collecting charitable donations in support of Ukraine. Funds will be transferred to the official accounts of...

You can donate to support Ukraine's defence, humanitarian demining, medical aid, the rebuilding of Ukraine or education & science here: u24.gov.ua

I just donated. Slava Ukraini!

28.02.2025 21:38 โ€” ๐Ÿ‘ 21    ๐Ÿ” 19    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 3

๐Ÿ‡บ๐Ÿ‡ฆ

28.02.2025 22:36 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Gegersen Lab The aim of the lab is to understand regulation of transcription and co-transcriptional processing in human cells

Another chance to join our group! Center for Gene Expression has 2 or more postdoc positions @ucph.bsky.social in wonderful Copenhagen. Want to join our team to work on transcriptional regulation? More information at: gregersenlab.com Deadline March 18. Apply here: jobportal.ku.dk/phd/?show=16...

21.02.2025 08:56 โ€” ๐Ÿ‘ 3    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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a cartoon of homer simpson and bart simpson sitting on a couch with the words join us above them . ALT: a cartoon of homer simpson and bart simpson sitting on a couch with the words join us above them .

We are looking to recruit a highly motivated postdoc with cell or molecular biology expertise. Excellent #epigenetics, #chromatin training & networking opportunities @qmulepigenetics.bsky.social
DM me for inquiries
pl apply/share tinyurl.com/m6jnksk5

13.02.2025 13:23 โ€” ๐Ÿ‘ 19    ๐Ÿ” 25    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
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We are recruiting! Center for Gene Expression has 2 or more open positions for PhDs @ucph.bsky.social. Come join our team to work on RNAPII and transcriptional regulation (gregersenlab.com). It's a wonderful city and amazing research environment. Deadline March 6. jobportal.ku.dk/phd/?show=16...

13.02.2025 20:09 โ€” ๐Ÿ‘ 6    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Pls. share: We're putting together a series on inequalities associated with academic mobility.

If you're a microbiologist and would like to share your experiences with visa difficulties, travel-related funding, mandated academic mobility requirements, etc, please write at tim@cell.com.

#MicroSky

06.02.2025 09:31 โ€” ๐Ÿ‘ 9    ๐Ÿ” 12    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Ever wondered how Pol II speed is controlled during productive elongation?
Our study reveals that the helicase RECQL5 triggers transcription braking, while the transcription-coupled DNA repair complex restores the elongation rate. #cryoEM #transcription

www.biorxiv.org/content/10.1...

03.02.2025 12:23 โ€” ๐Ÿ‘ 76    ๐Ÿ” 19    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 4
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The RNA-binding protein RSRC2 promotes mitotic fidelity by interacting with the lncRNA C1QTNF1-AS1 Mitotic fidelity depends on proper chromosome alignment at the spindle equator, a process known as chromosome congression, driven by well-established protein networks. Whereas RNA-binding proteins and...

๐Ÿ“ข1/12 Happy to share our first bluetutorial & our latest preprint. In this work, we discovered RSRC2 as a novel RNA-binding protein (RBP) with a dual function in cell division whose activity can be (lnc)RNA-mediated. #lncRNA #RBP #Mitosis
www.biorxiv.org/content/10.1...

23.01.2025 17:26 โ€” ๐Ÿ‘ 42    ๐Ÿ” 16    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 2
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We joined the Laboratory Efficiency Assessment Framework (LEAF), reduced laboratory waste and energy usage, and made the lab more sustainable overall.
And so we got the LEAF GOLD award!

24.01.2025 08:25 โ€” ๐Ÿ‘ 8    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Controlling Transcription Elongation and Termination: More Than a Means to An End

As you make have seen, there is a special issue of JMB on "Controlling Transcription Elongation and Termination: More Than a Means to An End" curated by my colleague here at Pitt Karen Arndt and by Steve Buratowski from Harvard Medical School ๐Ÿงช๐Ÿงต 1/ www.sciencedirect.com/science/arti...

27.11.2024 15:00 โ€” ๐Ÿ‘ 50    ๐Ÿ” 25    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 4
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Fateful Decisions of Where to Cut the Line: Pathology Associated with Aberrant 3โ€ฒ End Processing and Transcription Termination Aberrant gene expression lies at the heart of many pathologies. This review will point out how 3โ€ฒ end processing, the final mRNA-maturation step in thโ€ฆ

Pawel Grzechnik and Hannah Mischo discuss polyadenylation site recognition and what happens afterwards and how it can go wrong: Fateful Decisions of Where to Cut the Line: Pathology Associated with Aberrant 3โ€ฒ End Processing and Transcription Termination 14/ www.sciencedirect.com/science/arti...

27.11.2024 15:00 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

some good reviews there!

28.11.2024 09:33 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Look who's here
@pnas.org โœ”๏ธ
@science.org โœ”๏ธ
@naturecellbiology.bsky.social โœ”๏ธ
@natrevgenet.bsky.social โœ”๏ธ
@naturebiotech.bsky.social โœ”๏ธ
@naturemicrobiol.bsky.social โœ”๏ธ
@naturechemistry.bsky.social โœ”๏ธ
@genesdev.bsky.social โœ”๏ธ
@cellchembiol.bsky.social โœ”๏ธ
@genomeresearch.bsky.social โœ”๏ธ
@jcellbiol.bsky.social โœ”๏ธ

25.11.2024 13:48 โ€” ๐Ÿ‘ 504    ๐Ÿ” 237    ๐Ÿ’ฌ 34    ๐Ÿ“Œ 20
Diagram showing archaeal cells containing two chromosomes bound by proteins prior to cell division.

Diagram showing archaeal cells containing two chromosomes bound by proteins prior to cell division.

๐Ÿ“ข Interested in chromosomes and microbes thriving at the edge of life?PhD project in York-UK on chromosome segregation in #Archaea.

Supervised by me, @Steve Quinn & @georgerheath.bsky.social

www.findaphd.com/phds/project...
Open to Applicants Worldwide!

๐Ÿ“… January 6, 2025

#microsky #archaeasky

23.11.2024 13:10 โ€” ๐Ÿ‘ 33    ๐Ÿ” 32    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 2

done!

23.11.2024 08:20 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

done

22.11.2024 13:59 โ€” ๐Ÿ‘ 2    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

done!

22.11.2024 09:04 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Letโ€™s encourage our host institutes and organizations to move to Bluesky!
Follow those already here (UK starter pack), and let me know about others who have joined!

go.bsky.app/JMrhz8Q

22.11.2024 08:51 โ€” ๐Ÿ‘ 16    ๐Ÿ” 6    ๐Ÿ’ฌ 5    ๐Ÿ“Œ 0

Hello, Bluesky community!
We are the Division of Molecular and Cellular Function (MCF) in the Faculty of Biology, Medicine and Health at the University of Manchester.
Follow us for research updates and job opportunities!

21.11.2024 20:25 โ€” ๐Ÿ‘ 11    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Hi, can you add me to 1 and 2?

21.11.2024 17:02 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

Could you add me please?

20.11.2024 06:26 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

thanks Alper! @heick.bsky.social check here

19.11.2024 08:22 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

@grzechnikpawel is following 20 prominent accounts