Can't wait to release a 10-year-old birthday version for SeqKit!
- 10 years
- 2 papers, 3500 citations
- 20 contributors
- 40 subcommands
- 880 commits
- 500 issues
- 685.5K Bioconda total downloads
Thank you all, dear contributors and users!
I'll keep maintaining it.
github.com/shenwei356/s...
"Nobody will care about your work about sugar metabolism and transporters in Neurospora crassa"
Nobody can predict what can happen with your work.
www.sciencedirect.com/science/arti...
ShineGAL4 FLP-out clones
#Drosophila calling. Delighted to share our new collection of ShineGAL4 drivers for CNS, FB, muscles, enterocytes, oenocytes and MTs made by @vgirard.bsky.social, @sebsorge.bsky.social and colleagues @crick.ac.uk. All at Bloomington @bdsc.bsky.social
@dev-journal.bsky.social
tinyurl.com/4jpw9jd6
You still have 3 days to apply to the postdoc positions available in my lab 😀
🔬Come and work with us 🔬
Not something you see in textbooks very often: tripolar mitosis.
07.02.2026 08:00 — 👍 1577 🔁 275 💬 50 📌 22
This is a beautiful case of how real science happens & serious scientists work. Kudos to both set of authors: “This has been a humbling experience, but one that speaks to the self-correcting nature of the scientific endeavor.” www.science.org/doi/10.1126/...
06.02.2026 19:35 — 👍 112 🔁 50 💬 3 📌 2
One protein. One pathway. A whole germline fate.
New paper from my postdoc @mpi-bio-fml.bsky.social out in PNAS:
Germline fate determination by a single ARGONAUTE protein in Ectocarpus www.pnas.org/doi/10.1073/...
I'm sorry
23.01.2026 16:16 — 👍 7 🔁 0 💬 0 📌 0I am very happy (and a bit scared) to present to you what we have been working on over the last 4 years. This manuscript is exactly what I dreamt of when I started the lab and I could not be happier and prouder of the outcome!
10.01.2026 09:42 — 👍 153 🔁 62 💬 23 📌 2Ok, it's time to spill some tea🫖
05.01.2026 17:30 — 👍 1 🔁 0 💬 0 📌 0It’s out! Using cryo-ET in Dicty cells, we take a fresh in situ look at vaults. Surprisingly, we uncover vaults associated with ER and NE membranes, and find that many vaults enclose ribosomes in defined orientations, opening new avenues to their cellular function! www.biorxiv.org/lookup/conte...
16.12.2025 08:17 — 👍 106 🔁 39 💬 2 📌 5
Make a Bond movie academic
The World Is Not Enough: Increased frequency of microplastic clusters detection among Low Earth Orbit debris
Balanced polymorphism in a floral transcription factor underlies an ancient rhythm of daily sex alternation in avocado https://www.biorxiv.org/content/10.64898/2025.12.22.695989v1
25.12.2025 00:31 — 👍 82 🔁 25 💬 1 📌 11
RepeatMasker 4.2.3 released!
Fixes a sensitivity issue affecting staged searches in Rodentia species and adds support for BGZIP input files without in-place decompression. More details www.repeatmasker.org
RNA decay via the nuclear exosome is essential for piwi-mediated transposon silencing https://www.biorxiv.org/content/10.64898/2025.12.16.694471v1
17.12.2025 03:21 — 👍 15 🔁 11 💬 1 📌 1
Can one map the genome-wide binding (1) and its protein partners (2) simultaneously from the same sample?
Yes, one can. with CUT&ID ✂️🪪
Spearheaded — singlehandedly — by @annanordin.bsky.social
No need of transgenesis, cloning and overexpression.
Check it out, it's fast and its works.
The first paper of my PhD is now available as a preprint! 🎉
Transposable elements (TEs) don't just jump within fungal genomes, they also move extensively between species. In this study, we screened over 1,300 fungal genomes and found a conservative estimate of 5,500+ horizontal transfer events.
The story of how multiple RBPs cooperate to repress translation is now out in @cp-cellreports.bsky.social by @marcopayr.bsky.social and in a great collaboration with @hennig-lab.bsky.social!
www.cell.com/cell-reports...
It's great to see Radiohead live for the first time after listening to them since middle school. Too bad we didn't hear Everything in its Right Place and Karma Police today, but the setlist was still very good😊
05.12.2025 23:26 — 👍 3 🔁 0 💬 0 📌 0Not a huge fan of gtf and gff, because I had to deal with these formats and face the repercussions, but still a very nice thread!
05.12.2025 22:54 — 👍 0 🔁 0 💬 1 📌 0
It's insane that my hobby drives me up the freaking wall.
05.12.2025 13:41 — 👍 2 🔁 0 💬 0 📌 0
Great culture can save lives. Literally.
Amazing letter in today’s @thetimes.com about Tom Stoppard
R: We might as well be dead. Do you think death could possibly be a boat?
G: No, no, no... Death is...not. Death isn't. You take my meaning. Death is the ultimate negative. Not-being. You can't not-be on a boat.
R: I've frequently not been on boats.
G: No, no, no--what you've been is...not on boats
Coexistence of piRNA and KZFP Defense Systems: Evolutionary Dynamics of Layered Defense against Transposable Elements https://www.biorxiv.org/content/10.1101/2025.11.27.690821v1
30.11.2025 04:31 — 👍 3 🔁 2 💬 0 📌 0
Entire creation of new data that has no bearing upon any histological relevance. Remember LLM models are not open and we have no understanding of what NeuN, GFAP, or DAPI means in biological space within the LLM.
This is nonsense. But it looks at first blush as "real" to the uninformed.
Scary.
Another AI cover art. Sigh
22.11.2025 09:40 — 👍 40 🔁 9 💬 8 📌 0
🧬 PhD Position: Evolutionary & Comparative Genomics 🕷️
Join us at @uni-goettingen.de for a 3-year PhD (65% TV-L E13).
We will investigate the genomic & phenotypic impact of gene duplication across 233 arthropod genomes!
More infos 👇 and s.gwdg.de/eDrAAY
#Evolution #Genomics #Bioinformatics
Why are some reviewers so confidently nasty? Is it necessary to be like that?! Don’t they understand how much work goes into each manuscript and how damaging it can be for some people to read the vitriol? Or even consider that they might be wrong?!
18.11.2025 10:51 — 👍 34 🔁 5 💬 4 📌 0
A bittersweet acceptance: Between a manuscript and grief
Stefanie Williams @sillysciencelady.bsky.social shares the story behind her paper on the synaptonemal complex, including a tribute to her supervisor Scott Hawley, who passed away while Stefanie was completing the research.
