Artem Ilin

DNASE1L3 surveils mitochondrial DNA on the surface of distinct mammalian cells The extracellular space is a critical environment for discriminating self versus non-self nucleic acids and initiating the appropriate immune responses through signaling cascades to relay information ...

We’re excited to report work led by postdoc Jennifer Porat in the lab, finding that DNA accumulates on the surface of living cells and that the secreted extracellular protein DNASE1L3 can modulate its levels on B and T cells. With a new twist for ATAC-seq as well www.biorxiv.org/content/10.1...

Nowadays, too many institutions thinking ‘if we build it they will come’ combined with a shortsighted research funding model, a saturated Phd training sector, bloated admin load, and a general decline in creativity. Tough times indeed!

ATP-dependent remodeling of chromatin condensates reveals distinct mesoscale outcomes Adenosine triphosphate (ATP)–dependent chromatin remodeling enzymes mobilize nucleosomes, but how such mobilization affects chromatin condensation is unclear. We investigate effects of two major remod...

Today I am so pleased to present our work on how chromatin remodelers affect mesoscale chromatin organization.
www.science.org/doi/10.1126/...

Yes, yes, Europe has its benefits. Walkable cities. Cultural heritage. Amazing food. Little gun violence. Healthcare. Governments that are not shut down. But the number of website pop-ups asking one to accept cookies renders the continent pretty much unlivable.

It feels great to close 3 powerpoints, 10 word documents and 57 browser tabs after submitting the grant😌

Postdoctoral studies in next generation single cell lineage tracing of skin (scholarship) Do you want to contribute to top quality medical research? A postdoctoral scholarship is available in the lab of Emma R Andersson at the Department of Cell and Molecular Biology, Karolinska Institutet

👩‍🔬👨‍💻 Postdoc recruitment! 👨‍🔬👩‍💻

Join us to use next generation single cell lineage tracing (de Haan & He et al Science 2025) to resolve dermis developmental dynamics & mechanisms.

🚨 Deadline Oct 1st!! 🚨

Please re-post and help us spread the word far and wide! ✈

ki.varbi.com/en/what:job/...

A single brain infusion of miRNA targeting CAG repeats slows the progression of Huntington's disease by 75% in patients. This is something that I never thought I would see in my lifetime. www.uniqure.com/investors-me...

Kicked off a series on #Drosophila TE discovery and naming. The first post covers elements that predate the term "mobile element", and more. artemilin.dev/posts/te_nam...

A ring of cells deforms into a triangular keyhole in just 15 minutes. Meet the hindgut, a model for boundary-driven morphogenesis!

Out now in @pnas.org at doi.org/10.1073/pnas... with @zhaoshh.bsky.social, Alex Jacinto, Eric Wieschaus, Stas Shvartsman, @lepuslapis.bsky.social (1/8)

Hi! We are looking for a PhD to work on the cross talk between transposable elements, insects and intracellular bacteria on the bioinformatics side. The PhD would be supervised by @mariefablet.bsky.social and myself along with @nicolasparisot.bsky.social Deadline December 2025! Please share! #tesky

🧀🧀🧀‼️

The papers that I enjoyed reading this week, especially the second one:
artemilin.dev/posts/202509...

This gorgeous fella landed on my knee last week when I was in Vienna, chilled for a bit, didn't mind me touching him at all and then disappeared. Can anyone help identify? I would say that his length wasn't exceeding 6-7 mm. #entomology

This is figure 2, which shows M. ibericus queens lay males from two different species.

Living organisms are assumed to produce same-species offspring. A study in Nature reports a shift from this norm in Messor ibericus, an ant that lays individuals from two distinct species. go.nature.com/3V68MP0 🧪

STING cyclic dinucleotide sensing originated in bacteria - Nature Structures of prokaryotic homologues of STING permit the reconstruction of the evolutionary trajectory of its incorporation into metazoan innate immunity, and reveal a role for the conserved cGAS–STIN...

Together with @soreklab.bsky.social, our labs discovered that the human cGAS-STING pathway evolved from ancient bacterial proteins in CBASS anti-phage defense

www.nature.com/articles/s41...
www.nature.com/articles/s41...
www.nature.com/articles/s41...

Oh, look, mr. "I climbed Kilimanjaro" came to brag🙄

Hoher Dachstein, 2997 m, no sherpas, no oxygen. (Don't mind the cable car)

The autoregulation of a eukaryotic DNA transposon A DNA transposon, or ‘jumping gene’, controls its amplification within a genome through a competition between the enzyme multimers that are responsible for its mobility.

In all my obsession with RNA silencing, I realized I became blind to the significance of autoregulation of DNA transposons. Which is funny, because it was characterized in many ways by my Ph.D. advisor. From 2013: elifesciences.org/articles/00668

Translational research is digging for gold. Basic research is learning where and what to dig. The more funding is diverted to translation, the more we deplete the research ecosystem, driving the supplies of "gold" - immediately translatable findings and innovations - to unsustainably low levels.

SETDB yourself🫦

HDACreate your image💅🏻

DNMT3Beauty

#TEsky #RNAsky #RNAbiology

Climate models since the 1970s nailed it—most predicted global warming almost exactly as it happened.

Postdoc Postpunk

I don't know the exact number of Nobel Prize laureates who wrote cooking books, but here's a rösti recipe from Christiane Nüsslein-Volhard: artemilin.neocities.org/post/250817_nv

We are hiring a lab technician! Join our group studying signaling networks in #Drosophila, with a possibility to carry out a research project. Please RT.
Job posting: employmentopportunities.umb.edu/boston/en-us...
Veraksa lab website:
www.faculty.umb.edu/alexey_verak...

I'm starting to think that conda isn't the best option for isolated environments. I have just 7 envs, some of which run a couple of dedicated tools and the number of files required to run them is gigantic. Mind you, today, the large file number exerts much harder strain on storage than the file size

🔬 From our August issue (rupress.org/jcb/issue/22...): A confocal image of a #Drosophila egg chamber where #actin filaments are labelled with rhodamine phalloidin and color-coded to represent different depths within nurse cells. From Ghosh et al.: rupress.org/jcb/article/...

Did you know #fruitflies ovulate roughly 70 times a day? This makes #Drosophila a powerful model for studying the #genetics behind #ovulation in humans.

Here's a stunning look at fly ovaries under a #fluorescent microscope. Each blue dot is a cell nucleus. The beauty of #DrosophilaOogenesis!

It's so much easier to destroy than to build, and the U.S. admin once again proves it has firmly stepped onto the path of total scientific destruction