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Longhua Guo

@longhuaguo.bsky.social

Genetics | Genomics | Aging, Regeneration and Rejuvenation. Assistant Professor @ U of Michigan. Lab: guolabagingreg.com

285 Followers  |  127 Following  |  5 Posts  |  Joined: 13.11.2024  |  1.6072

Latest posts by longhuaguo.bsky.social on Bluesky

ReBilD: Emerging Leaders in Regenerative Biology and Development 2025 โ€“ MDI Biological Laboratory

Registration for โ€œReBilD 2025โ€ (Emerging Leaders in Regenerative Biology and Development) is now open! Gain hands-on training with diverse regenerating animal models and attend daily lectures by leaders in the field. Please RT. mdibl.org/course/rebil... @mdibiolab.bsky.social

02.12.2024 19:51 โ€” ๐Ÿ‘ 14    ๐Ÿ” 11    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Nature Aging How long will we live? And how much of that time will comprise a healthy life? What is aging, and can we stop or even reverse the aging process? What is the ...

Rejuvenation in planarians. Check out the details in this link: www.nature.com/nataging?gcl... @nataging.nature.com

20.05.2025 18:53 โ€” ๐Ÿ‘ 4    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Decelerated aging in old mice skeletal muscle after regeneration. This phenotype measured with DNA methylation clock was further enhanced with senolytics treatment.

22.04.2025 17:53 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Cool data here. We have some mouse data (regeneration, not amputation) that supports this! Stay tuned and great stuff @longhuaguo.bsky.social #myoblue @natureaging.bsky.social

13.04.2025 12:08 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Regeneration leads to global tissue rejuvenation in aging sexual planarians - Nature Aging The freshwater planarian S. mediterranea is an important model organism for regeneration research but its use in aging research is little explored and S. mediterranea is commonly referred to as immort...

The article: Regeneration leads to global tissue rejuvenation in aging sexual planarians
www.nature.com/articles/s43...

12.04.2025 18:21 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Aging, regeneration and whole-body rejuvenation in long-lived planarians - Nature Aging We identified aging-associated changes in sexual strains of the extremely long-lived planarian Schmidtea mediterranea. Following amputation and regeneration in older animals, aging-associated phenotyp...

The summary: Aging, regeneration and whole-body rejuvenation in long-lived planarians
www.nature.com/articles/s43...

12.04.2025 18:21 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

We identified aging-associated changes in sexual strains of the extremely long-lived planarian Schmidtea mediterranea. Following amputation and regeneration in older animals, aging-associated phenotypes were reversed to youthful states.

12.04.2025 18:21 โ€” ๐Ÿ‘ 5    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 1
Preview
Regeneration leads to global tissue rejuvenation in aging sexual planarians - Nature Aging The freshwater planarian S. mediterranea is an important model organism for regeneration research but its use in aging research is little explored and S. mediterranea is commonly referred to as immort...

Online now! Dai et al. report age-associated physiological and molecular changes in the sexual lineage of S. mediterranea, and global reversal of such changes after regeneration.
doi.org/10.1038/s435...

07.04.2025 07:26 โ€” ๐Ÿ‘ 1    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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We are grateful to @isrbio.bsky.social for their support of the ReBilD course @mdibiolab.bsky.social. mdibl.org/course/rebil... Please RT. ๐Ÿ™Œ

07.02.2025 17:51 โ€” ๐Ÿ‘ 7    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

We need to have a โ€˜code of conductโ€™ for reviewing manuscripts, like (1) if you say that something is not novel then provide the reference. (2) If you propose an experiment, state precisely to which claim it is crucial. (3) If you want to say something nasty then sign your name.

17.11.2024 14:46 โ€” ๐Ÿ‘ 228    ๐Ÿ” 36    ๐Ÿ’ฌ 12    ๐Ÿ“Œ 3

@longhuaguo is following 20 prominent accounts