Chaitanya Dingare

Congratulations!

Paper alert! I am really pleased to share the final version of the work led by Irène Amblard in the team on a regulatory switch controlling Cdx2 expression during posterior body development! #regulatorylogic #devbio @mrc-lms.bsky.social @imperialmed.bsky.social

Nerve-to-cancer transfer of mitochondria during cancer metastasis
www.nature.com/articles/s41...

GATA6 Mediates Endoderm and Mesoderm Progenitor Fate Driven by WNT and NODAL Signaling https://www.biorxiv.org/content/10.1101/2025.06.20.660704v1

An advanced head-to-tail mouse embryo model with hypoxia-mediated neural patterning https://www.biorxiv.org/content/10.1101/2025.06.17.660116v1

It’s out! 🥳

www.science.org/doi/10.1126/...

The weekly Metabolites-driven PTMs focusing on cancer Biomed News is out ☺️ biomed.news/bims-prolim/...

Congratulations! The images look amazing!

If you’ve ever wondered how those intricate gill structures emerge—and how gills develop throughout a zebrafish’s lifespan—check out my new preprint!
We dive into the development of gills and their vasculature in detail.
Huge thanks to @vlecaudey.bsky.social for the support🐟

#zebrafish #microscopy

New preprint from the lab! Beautiful work by @mathpreu.bsky.social, who delved into the early development of gills and their intricate vasculature. Thanks to the Clusterproject ENABLE and @goetheuni.bsky.social for the funding! www.biorxiv.org/content/10.1...

Metabolites are not genes

COMMENT | KS Li, X Su & T Huan (Rutgers U, UBC):

Metabolites are not genes — avoiding the misuse of pathway analysis in #metabolomics.

https://bit.ly/4kIGbtI ?utm_source=bluesky&utm_medium=social&utm_campaign=natmetab

A lipid metabolism defect is an underlying contributor to Diamond Blackfan anemia syndrome https://www.biorxiv.org/content/10.1101/2025.05.22.654334v1

Signaling and Mechanics influence the number and size of epithelial rosettes in the migrating zebrafish Posterior Lateral Line primordium https://www.biorxiv.org/content/10.1101/2025.05.17.650326v1

Experimental embryology postdoc available in my lab at the @biology.ox.ac.uk @ox.ac.uk working on the evolution of vertebral counts. Reach out if you’re passionate about EvoDevo, enjoy lab work and microscopy and are into or could get into cichlid fishes. Deadline on the 16th June. Please share!

Interesting work on #morphogen (BMP4, Wnt8) mobility and HSPGs in Xenopus🐸

“We propose a model in which Yap1, together with Tead proteins, ensures that the [posterior lateral line primordium] contains a sufficient number of cells before migration begins.”

New work from @vlecaudey.bsky.social 👩‍🔬

Vgll4 Proteins limit Organ Size in Zebrafish through Yap1-Dependent and -Independent Mechanisms https://www.biorxiv.org/content/10.1101/2025.05.08.652796v1

New preprint from the lab!! Project was initiated by @chaitanyadingare.bsky.social and continued by Alicia Lardennois with quite some people involved on the way 🤗

Two transcriptional modules that control mammalian #gastrulation that are functionally linked through their GRNs www.biorxiv.org/content/10.1... and paced by interactions between Wnt and Nodal signalling
Great collaboration with S Arnold and K McDole's labs #gastruloids

Why does the forebrain expand dramatically while other neural regions grow less? Our new publication reveals progenitor metabolism critically shapes region-specific brain growth. Thread below. authors.elsevier.com/a/1k-udL7PXu...

Intracellular metabolic gradients dictate dependence on exogenous pyruvate Nature Metabolism - Jackson et al. provide insight into how metabolic adaptations that accompany cell state transitions drive reliance on exogenous nutrient availability, focusing on pyruvate as a...

I'm excited to share our latest story from the
@lydiafinley.bsky.social lab, where we show that it's not just whether cells take up nutrients that matters, but how and where those metabolites are used. Out now in @naturemetabolism.bsky.social: rdcu.be/ejFTs 1/

📢 Fresh off the press and featuring new exciting experiments! 🧪
We show how glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling - happy to finally share this 😊
doi.org/10.1016/j.st...

B2B with @jesseveenvliet.bsky.social lab: doi.org/10.1016/j.st... 🤩

Glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling Stapornwongkul and colleagues investigate the role of metabolism during germ layer specification using a stem cell-based model system for gastrulation. They demonstrate that beyond its bioenergetic function, glycolysis also acts as an upstream regulator of important developmental signaling pathways, thereby controlling mesoderm and endoderm induction in a dose-dependent manner.

Online Now! Glycolytic activity instructs germ layer proportions through regulation of Nodal and Wnt signaling #stemcells

Congratulations!

Embryo-scale single-cell chemical transcriptomics reveals dependencies between cell types and signaling pathways https://www.biorxiv.org/content/10.1101/2025.04.03.646423v1

🎉Congratulations to PoL PI and group leader at @mpi-cbg.de Rita Mateus @ritamateus.bsky.social and collaborators for being awarded a HFSP Early Career Grant!

Their project is titled 'MetaCrystal: Metabolic principles of intracellular crystallization'. Learn more on our website: tud.link/y56cmr

Congratulations! Looking forward to reading exciting science from your group!

Are you interested in being involved with the undergraduate practical teaching we offer?
We are looking for a Technician to come and join our team.

📅Apply by 02 March
➡️https://www.jobs.cam.ac.uk/job/50264/

a fully grown dalmatian is leaning on a blanket on a couch. he’s smiling with his tongue hanging out a little bit. he has two heart-shaped dots on his face, one on each eye, making him the dog version of the heart eyes emoji.

This is Charlie. He has literal heart-eyes. 14/10 would be an honor to pet (IG: charlie.the.dalmatian)

Development of the zebrafish anterior lateral line system is influenced by underlying cranial neural crest The mechanosensory lateral line system of aquatic vertebrates comprises a superficial network of distributed sensory organs, the neuromasts, which are arranged over the head and trunk and innervated b...

This is my first every pre-print! Yes I am late to the party - but happy to make this entrance. Congrats to all my co-authors on their lovely work. www.biorxiv.org/content/10.1...