Calum Bain

Our latest preprint, led by @lizihegarty.bsky.social & aided by @erinwatson.bsky.social shows that fixation time matters when it comes to visualising #macrophages in #salivarygland & other epithelia.We find 1hr allows detection of mac subsets while preserving architecture. With @bainlab.bsky.social

Fixation matters: duration in fixative prior to immunofluorescent analysis directly impacts macrophage visualisation in epithelial tissues https://www.biorxiv.org/content/10.64898/2026.02.13.705745v1

⌛Time is running out!

Abstract submission closes tomorrow. Don't miss your chance to present your work at #SIGNET26

Join the Scottish immunology community in Perth to network, share the latest findings and explore new breakthroughs


🔗 Find out more https://bit.ly/49VL6FA

Allergy at AIC, part 2 - Mucosal Immunology Podcast | iHeart <p>This episode includes more discussions from the Autumn Immunology 2025 Conference 2025 conference. KathrynKnoop sits down with Drs.  Caroline Sokol and Stephanie Eisenbarth to discuss food and skin...

This #MucosalMonday @bainlab.bsky.social and @lizihegarty.bsky.social are in the Authors Corner discussing their recent #macrophage work from MI. Then @kknoop.bsky.social brings you more allergy and anaphylaxis with Caroline Sokol and @stephanieeisen.bsky.social:
www.iheart.com/podcast/269-...

Very nice commentary of @lizihegarty.bsky.social’s recent paper in @mucosalimmunol.bsky.social by Florent Ginhoux and colleagues #macrophage #colon @bainlab.bsky.social

Thanks to Peiliang Cai, Zhaoyuan Liu and @florentginhoux.bsky.social for their great Commentary on our recent study led by @lizihegarty.bsky.social proposing a framework for defining murine colonic macrophages @mucosalimmunol.bsky.social

@edinuni-irr.bsky.social
@uofgsii.bsky.social

Merry Christmas to all colleagues, collaborators and friends. I hope everyone has a good break and some rest. See you in 2026!

Why we have to continue with animal testing for medical research | Letters Letters: Dr Robin Lovell-Badge and Prof Emma Robinson respond to an editorial on using new technologies to reduce the reliance on animal experiments

Key points on the need for continued animal use in scientific research. www.theguardian.com/science/2025...

Thanks for sharing @mucosalimmunol.bsky.social. This work was led by @lizihegarty.bsky.social during her PhD @edinuni-irr.bsky.social funded by @wellcometrust.bsky.social. Now being continued after our relocation to @uofgsii.bsky.social.

Might be of interest to @emds2025.bsky.social attendees!

A big thanks to Lizi for her hard work - started in the midst of the pandemic. Thanks to all collaborators who helped make this work possible, to the reviewers and to the editorial team at Mucosal Immunology for the efficient process.

Do tissue resident #macrophages survive through intestinal #inflammation? Are they terminally differentiated or can they adapt? @lizihegarty.bsky.social asked these Qs during her @wellcometrust.bsky.social PhD and her findings are now published @mucosalimmunol.bsky.social

@edinuni-irr.bsky.social

Hypoxia induces histone clipping and H3K4me3 loss in neutrophil progenitors resulting in long-term impairment of neutrophil immunity - Nature Immunology Walmsley and colleagues report that systemic hypoxia induces persistent loss of histone H3K4me3 marks and epigenetic reprogramming in neutrophil progenitors, resulting in long-term impairment of subse...

#Neutrophils are short lived cells, yet in ARDS display long term changes, with impaired neutrophil functions even after 6 months. How can they undergo long term reprogramming?

this is what @mas-g.bsky.social answered, mapping changes to neut. progenitors. @walmsley-lab.bsky.social #immunosky

Calum Bain stood on the majestic McEwan Hall stage in front of a podium below a large screen introducing the meeting and welcoming delegates

Mariola Kurowska-Stolarska stood on stage below a large screen presenting recent findings on dendritic cell heterogeneity in rheumatoid arthritis.

Gareth-Rhys Jones stood on stage below a large screen discussing the role of monocyte-derived activin in intestinal repair.

Ed Roberts stood on stage, with the camera straight on, discussing decoding the roles of migratory and resident dendritic cells in protective immune responses

🆕 | @uofgsii.bsky.social researchers played a key role in delivering the 38th EMDS meeting, held 16–18 Sep in Edinburgh.

Led by @bainlab.bsky.social and @mariolaks.bsky.social with colleagues at @edinburghuni.bsky.social, the event hosted over 260 delegates.

🔗 More: www.gla.ac.uk/schools/infe...

Did you attend #EMDS2025? If so, please take time to tell us about your experience in the survey you received. This will help the organisers of #EMDS2026 (Amsterdam, November 2026)

@edinuni-irr.bsky.social
@britsocimm.bsky.social

Well done @lizihegarty.bsky.social. You are an exemplar postdoc - hardworking, well-read, conscientious, supportive, collegiate, all while being good fun (and expert in where to dine!!). Delighted to have you as a colleague.

@edinuni-irr.bsky.social
@uofgsii.bsky.social
@britsocimm.bsky.social

Great to see this out for all to see after a lot of hard work by @lizihegarty.bsky.social and @bainlab.bsky.social. Colonic #macrophages persist but are transcriptionally altered post- #inflammation in a mouse model of #colitis.

Delighted all of @lizihegarty.bsky.social's hard work as paid off. She shows that tissue resident colonic #macrophages persist through #inflammation and adapt to aid tissue repair.

Lovely collaborative work with colleagues @edinuni-irr.bsky.social and beyond. 🙏🏻

@uofgsii.bsky.social

Amazing! Well done @lizihegarty.bsky.social. Thoroughly deserved. You contribute so much to the Emmerson and Bain labs.

@edinuni-irr.bsky.social
@uofgsii.bsky.social

📣 Journal Editors at EMDS2025:Scotland Edition

Giuliana Clemente, Associate Editor (Immunology) @natcomms.nature.com, will be in Edinburgh at #EMDS2025 this week. Reach out to her to discuss your work.

@efis-immunology.bsky.social
@britsocimm.bsky.social

We have a new Postdoc position advertised as part of our recent long-term Wellcome funding to join an established Postdoc and technician. I’m so excited to explore the role of the glycocalyx in CNS-inflammation. So many tools and expertise to work with! www.jobs.manchester.ac.uk/Job/JobDetai...

📣 Journal Editors at EMDS2025:Scotland Edition

@gaiajexpmed.bsky.social, Deputy Editor @jem.org, will be in Edinburgh at #EMDS2025 next week. Reach out to her to discuss your work. Also, check out the Special Collection @jem.org on #macrophage & #dendriticcells

@efis-immunology.bsky.social

📣 Journal Editors at #EMDS2025

@claireolingy.bsky.social , Senior Editor at #Science #Immunology @aaas.org , will be at EMDS2025, so be sure to reach out to her to discuss your work.

@efis-immunology.bsky.social @britsocimm.bsky.social

Another exciting opportunity @dunnschool.bsky.social !

Come and be a colleague to a great group of scientists working on the fundamental mechanisms underlying disease, and how to transform health

Please help us find great applicants

Speaker Highlight - William (Bill) Agace

It's not too late to join us at #EMDS2025 to hear from Bill Agace about their work dissecting dendritic cell diversity in #Crohn's disease.

www.emds2025.com

@britsocimm.bsky.social @efis-immunology.bsky.social

[Background photo: Andrew Perry]

Still time to register for #EMDS2025 in the wonderful city of Edinburgh!

All details including invited & selected speakers and their abstract details at www.emds2025.com

Plus, the chance to take part in a traditional ceilidh!

The #Travel4Expertise Grant offers up to USD 2,500 to support care-related costs while you travel for hands-on training or advanced techniques.
🔗 Learn more and apply: https://loom.ly/en-kO9s
#GlobalImmunology #GenderEquity #ImmunologyWithoutBorders

Speaker Highlight - Clare Bennett

Join us at #EMDS2025 to hear from @clarebennettslab.bsky.social from @ucl.ac.uk about the curious case of the Langerhans cell - DC or #macrophage?

Register today at www.emds2025.com

@efis-immunology.bsky.social

Speaker Highlight - Samanta Mariani

#Macrophages support #HSC development in health but what happens in the context of leukaemia? Join us at #EMDS2025 to hear from Samanta Mariani from @edinuni-irr.bsky.social to find out more. Register today at www.emds2025.com

@efis-immunology.bsky.social

Speaker Highlight - Jan Van den Bossche

Adding to the #macrophage #metabolism masterclass at #EMDS2025 is @immunometlab.bsky.social from @amsterdamumc.bsky.social

Register today at www.emds2025.com

@britsocimm.bsky.social
@efis-immunology.bsky.social
@yefis-immunology.bsky.social

Looking forward to catching up @martinguilliams.bsky.social and hearing what you and the group have been up to.