Mohsen Sadeghi

Chicago’s beloved ‘rat hole’ was actually made by a squirrel Scientists reopen the case of “splatatouille”

Very important finding:

www.science.org/content/arti...

Mitochondria expel tainted DNA — spurring age-related inflammation Organelles spit out DNA contaminated with damaging components, leading to the activation of inflammatory enzymes, mouse experiments show.

This is quite interesting. Mitochondrial 'DNA expulsion' triggers inflammation pathways.

www.nature.com/articles/d41...

Jane Goodall, Eminent Primatologist Who Chronicled the Lives of Chimps, Dies at 91

Sad news: Jane Goodall has died. She did more than any other human for our understanding and appreciation of our closest relatives, the chimpanzees.

That chimpanzees are Endangered tells you everything about our species and about what made her so exceptional.

www.nytimes.com/2025/10/01/o...

Who invented convolutional neural networks? Who invented convolutional neural networks?

Very interesting:
people.idsia.ch/~juergen/who...

Somebody help these poor predators. They are in mortal danger, apparently.

When you don't bother to initiate your spam bot:

Come work at Nature Methods! A dream job. I know from experience 😄

Peak zero-shot learning:

American "Battle Royale"...

It's not Onion, and we're comfortably away from 1. April.

Finding Beauty and Truth in Mundane Occurrences | Quanta Magazine The physicist Sidney Nagel delights in solving mysteries of the universe that are hiding in plain sight.

This is an interesting read. I knew about Nagel's work on coffee stains. And when I read this part, "...I mean, would you give tenure to someone who’s studying coffee stains?" it made me sad. There is less and less room for beauty and curiosity in science.
www.quantamagazine.org/finding-beau...

Is it OK for AI to write science papers? Nature survey shows researchers are split Poll of 5,000 researchers finds contrasting views on when it’s acceptable to involve AI and what needs to be disclosed.

I'm a bit surprised by these numbers. There's bigger resistance than I would've guessed:
www.nature.com/articles/d41...

Absolute power move.

One of those days in the lab.

'Biological reality': What genetics has taught us about race As US President Donald Trump takes aim at the Smithsonian Institution for "anti-American ideology", Adam Rutherford examines what the science of genetics has taught us about race.

Another piece of scientific fact put into question by Trump's administration, where refuting the antiquated idea of biological race called "anti-american idealogy". It is interesting how similar patterns emerge with fascism.
www.bbc.com/future/artic...

Oh, I'm ever so fascinated by "La trompette de la Mort"!

The Blue Origin flight showcased the utter defeat of American feminism | Moira Donegan The trip leaned on a vision of women’s empowerment that is light on substance and heavy on a childlike, girlish silliness

www.theguardian.com/commentisfre...

Oh, this was my favorite game on #C64! took forever to load each battle scene, but totally worth it!

Germans have a perfect way of putting this, "April, April, der macht, was er will!"

Those trying to understand the tariffs as economic policy are dangerously naive.

No, the tariffs are a tool to collapse our democracy. A means to compel loyalty from every business that will need to petition Trump for relief.

1/ A 🧵 to explain his plan and how we fight back.

YouTube video by lftkryo Making 8-bit Music From Scratch at the Commodore 64 BASIC Prompt

You're my kind of crazy (and old) if you find this coding walkthrough for controlling SID chip in C64 using machine code inside BASIC interpreter where IRQ mapping is used to turn the screen content into a real time music controller, the coolest thing.

www.youtube.com/watch?v=ly5B...

Machtmissbrauch an Max-Planck-Instituten – DW – 13.03.2025 Max-Planck-Institute locken mit ihrem Ruf und Top-Forschungsbedingungen. Aber der Nachwuchs wirft Vorgesetzten Mobbing vor. Eine Recherche von DW und "Der Spiegel" zeigt: Beschwerdeverfahren versagen ...

Leider finde ich es bei den Max-Planck-Instituten weniger überraschend:

p.dw.com/p/4rhHK

Curtis Yarvin Says Democracy Is Done. Powerful Conservatives Are Listening. The once-fringe writer has long argued for an American monarchy. His ideas have found an audience in the incoming administration and Silicon Valley.

I found this interview with Curtis Yarvin quite helpful in understanding a lot of non-sensical directions the US is headed. I am also genuinely frightened by how hard it has become to state the obvious in the face of the "techno-monarchy" ideas.

www.nytimes.com/2025/01/18/m...

openRxiv has arrived!

We’re thrilled to announce the launch of openRxiv as an independent, researcher-led nonprofit to oversee bioRxiv and medRxiv, the world’s leading preprint servers for life and health sciences.
openrxiv.org/introducing-...

#openRxiv #OpenScience #Preprints #bioRxiv #medRxiv

Putin agrees to help broker talks between Trump and Iran: reports Russia "is ready to do everything in its power" to help facilitate negotiations between US and Iran.

We're stuck on this weird timeline.

www.newsweek.com/putin-agrees...

Watch angry exchange between Trump and Zelensky at White House The US president accused the Ukrainian leader of being disrespectful in a tense meeting in the Oval Office.

For me, this altercation was the first time a leader of a country acted in front of Trump the way it made sense. Not surprisingly, as is the case with all bullies, it also brought the worst in Trump out. Need more of this.
bbc.com/news/videos/...

Hello blue sky! Excited to be a part of the scientific community on this platform.

OMG, great stand up comedy is going on at CPAC. 🤣

Honored to be part of this amazing work, where synaptic vesicle fusion has been studied by a clever combination of optogenetic stimulation and cryoET.

I welcomed the opportunity to contribute with mesoscopic simulations involving dynamic membranes. Preprint: www.biorxiv.org/content/10.1...

Excited to share our new preprint "Dynamic nanoscale architecture of synaptic vesicle fusion in mouse hippocampal neurons" www.biorxiv.org/content/10.1...

We combine optogenetic stimulation of neurons with in situ cryo-ET to characterize membrane dynamics during synaptic vesicle fusion ❄️🔬⏱️

Some effective eye bleach for weekend use!
😍