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Maggie Smith

@factor50.bsky.social

Retired Professor of Microbiology in the UK. Love bacteriophages, Streptomyces, fun, outdoors, culture and politics.

101 Followers  |  87 Following  |  20 Posts  |  Joined: 22.02.2025  |  1.8768

Latest posts by factor50.bsky.social on Bluesky

Great to see this is out now. Congratulations to all the authors.

07.02.2026 11:38 β€” πŸ‘ 8    πŸ” 4    πŸ’¬ 1    πŸ“Œ 0

Thanks Emm. I saw a draft. Good to see it’s out there!

07.02.2026 11:35 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Alison Smith, Author and Emeritus Fellow at the John Innes Centre said, β€œWe were inspired to write this book by the stimulating, creative and supportive environment provided by our JIC and TSL colleagues. It is intended to provide a new generation of plant scientists with an appreciation of the wealth and breadth of radically new knowledge and technologies in plant science. The book also reveals some of the exciting opportunities for fundamental discovery and innovation in plant science to help tackle global challenges including sustainable food production, environmental pollution, climate change and biodiversity loss.”

Alison Smith, Author and Emeritus Fellow at the John Innes Centre said, β€œWe were inspired to write this book by the stimulating, creative and supportive environment provided by our JIC and TSL colleagues. It is intended to provide a new generation of plant scientists with an appreciation of the wealth and breadth of radically new knowledge and technologies in plant science. The book also reveals some of the exciting opportunities for fundamental discovery and innovation in plant science to help tackle global challenges including sustainable food production, environmental pollution, climate change and biodiversity loss.”

πŸ“’ New plant science textbook

Staff and alumni from our institute and @thesainsburylab.bsky.social have recently published Essential Plant Biology, a new textbook presenting current and comprehensive knowledge of plant biology 🌱

30.01.2026 18:10 β€” πŸ‘ 20    πŸ” 11    πŸ’¬ 1    πŸ“Œ 0

Our latest CRISPR ring nuclease paper focusses on Csx15 - which seems to act as of a sponge as well as a canonical phosphodiesterase. Great work led by @haotianchi.bsky.social

www.biorxiv.org/content/10.6...

22.01.2026 08:57 β€” πŸ‘ 36    πŸ” 20    πŸ’¬ 0    πŸ“Œ 0

Catch this if you can! Highly recommended.

21.01.2026 09:33 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Preview
Medieval Myths Bingo There is so much β€œfake history” going around about the Medieval Era that I decided to write this article and create this; There are a lot of myths and misconceptions about β€œThe&#8…

Here's just a few about the middle ages...
fakehistoryhunter.net/2019/09/10/m...

07.01.2026 01:24 β€” πŸ‘ 9    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

Congratulations Mike! Well deserved. πŸ‘πŸ‘πŸ‘

20.12.2025 16:24 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Professorial Appointment within the Manchester Institute of Biotechnology:Manchester Institute of Biotechnology Applications are invited for a professorial appointment to be based in the Manchester Institute of Biotechnology (MIB) at the University of Manchester (UoM). The successful candidate will join a dynamic research environment at an exciting time and will help shape the institute research priorities and national/international profile. We are open to high quality applications from across the broad engineering biology and biotechnology landscape. Specific areas of interest include but are not limited to chemical biology of disease related proteins, natural product biosynthesis and enzyme discovery; structural biology and mechanistic enzymology; and microbial engineering.

Manchester Institute of Biotechnology is looking for a new Professor. There are a few priority areas including microbial engineering (broadly defined, from pathways to cells to microbiomes). Closing 12 Jan.
Join us in the best city in the UK 😜
www.jobs.manchester.ac.uk/Job/JobDetai...

20.12.2025 12:21 β€” πŸ‘ 15    πŸ” 25    πŸ’¬ 1    πŸ“Œ 1

So happy to see Mark recognised for his incredible work. Over a ~40 year career he and his group discovered ECF sigma factors, characterised many key developmental regulators of the Streptomyces lifecycle, and identified new mechanisms of bacterial gene regulation, antibiotic action and resistance.

11.12.2025 20:23 β€” πŸ‘ 29    πŸ” 10    πŸ’¬ 3    πŸ“Œ 0
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Highlights from our recent participation!

Members of the Multi-Defence Consortium presented both talks and posters on phage defence systems β€” showcasing exciting progress across the field.

Great discussions, great science, and we’re excited to share more soon!
#MicroEvo25

27.11.2025 17:26 β€” πŸ‘ 20    πŸ” 4    πŸ’¬ 1    πŸ“Œ 1

Congratulations to all the Microbiology Society Prize winners!

19.11.2025 15:43 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Congratulations!

14.11.2025 18:26 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Exciting news! I have two positions open in my lab at the UoManchester: one PDRA and one Research Tech.
Join our team to study evolutionary mycology and help us understand antifungal resistance in fungal pathogens. A fantastic opportunity to join the brilliant Manchester Fungal Infection Group!

05.11.2025 15:35 β€” πŸ‘ 17    πŸ” 33    πŸ’¬ 2    πŸ“Œ 0

Improved LSRs for integrating DNA into the human genome. Great work!

08.11.2025 10:29 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thanks Emm! Very interesting read! And soooo much work! Good to see progress on efficiency and specificity of LSRs as genome integration tools.

08.11.2025 10:24 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Preview
All the world’s a phage | PNAS A renewed interest in bacteriophages has emerged from the explosive discovery of the complex pan-immune bacterial defense system and a revival of t...

#microsky #phagesky
Mycobacterium #phage review by Graham Hatfull covering the state of the art

www.pnas.org/doi/10.1073/...

31.10.2025 10:00 β€” πŸ‘ 21    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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R.I.P Hamilton Smith, 1978 Nobel Laureate for the discovery of type II restriction-modification systems (HindII).

26.10.2025 18:54 β€” πŸ‘ 91    πŸ” 26    πŸ’¬ 1    πŸ“Œ 1
Preview
Expanding the Landscape of BREX Diversity: Uncovering Multi-Layered Functional Frameworks and Identification of Novel BREX-Related Defense Systems Despite extensive scrutiny of BREX systems, several overarching questions persist regarding the functional modalities of individual components and the collective mechanistic framework underlying their...

www.biorxiv.org/content/10.1...

#phagesky on BREX #phage defence

16.10.2025 06:52 β€” πŸ‘ 10    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Preview
CHRIS ADDISON'S INCOMPLETE GUIDE TO CHAMBER MUSIC CHRIS ADDISON'S INCOMPLETE GUIDE TO CHAMBER MUSIC - Music in the Round %

TONIGHT! Come along if you’re within reach of Sheffield and/or on a mercy dash from the south to get some Hendo’s. This is going to be fab. I’m (a) super excited; (b) on my way!

musicintheround.co.uk/events/chris...

10.10.2025 09:30 β€” πŸ‘ 24    πŸ” 7    πŸ’¬ 0    πŸ“Œ 1
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Thanks Sheffield, that was a super fun evening!

10.10.2025 09:45 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0

This was really fun. See it if you can.

10.10.2025 09:14 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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VOM-UK Conferences - NU-OMICS Viruses of Microbes UK (VoM-UK) Conference The Virus of Microbes UK (VoM-UK) Conference is hosted by Microbiome Excellence Peak of Excellence at Northumbria University. This two-day conference takes place annually at the end of January/beginning of February and is a chance for researchers to gather and share their knowledge. The VoM-UK conference is designed to […]

hosting.northumbria.ac.uk/nu-omics/vom...

#phagesky #phage #microsky

Come and join us for Viruses of Microbes UK 2026 at @northumbriauni.bsky.social ! Fantastic chance for ECRs to showcase their work πŸ™‚

09.10.2025 09:21 β€” πŸ‘ 19    πŸ” 14    πŸ’¬ 0    πŸ“Œ 1
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Huge congratulations to Emma Davis, the winner of 2025's Early Career Microbiologist of the Year prize! We agree with Emma that all of the finalists' talks were brilliant and a massive well done to everyone involved!

07.10.2025 17:17 β€” πŸ‘ 33    πŸ” 8    πŸ’¬ 2    πŸ“Œ 4
University of Glasgow - Postgraduate study - Centres for Doctoral Training - NorthWest Biosciences - Our Projects - Underpinning Bioscience - Paul A Hoskisson

Come and work with me and @ariannebabina.bsky.social on #Streptomyces evolution and antibiotic production

Origins of a tangled bank: Adaptation and evolution in antibiotic-producing Streptomyces

www.gla.ac.uk/postgraduate...

please repost

30.09.2025 11:02 β€” πŸ‘ 36    πŸ” 56    πŸ’¬ 0    πŸ“Œ 3

Congratulations! Good choice by REF.

04.09.2025 15:08 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Prophages block cell surface receptors to preserve their viral progeny - Nature Zip promotes the accumulation of free phages in bacterial lysogen communities, safeguarding phage progeny.

Nature research paper: Prophages block cell surface receptors to preserve their viral progeny

go.nature.com/3IwINxb

18.07.2025 09:56 β€” πŸ‘ 20    πŸ” 5    πŸ’¬ 0    πŸ“Œ 2

Ouch! Wishing a fast recovery!

21.08.2025 18:48 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

My humble offering: Evolutionary relationships among diverse bacteriophages and prophages: all the world's a phage pubmed.ncbi.nlm.nih.gov/10051617/

04.08.2025 09:07 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Happy Birthday, mucker!! I hope you have a lovely day. You too Geertje!!

04.08.2025 09:00 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 2    πŸ“Œ 0

Super proud of amazing lab alumnus @mbottery.bsky.social who has been awarded a prestigious @wellcometrust.bsky.social fellowship to grow his lab @officialuom.bsky.social studying the evolution of fungal pathogens!

Mike has multiple postdoc positions available on his exciting project (details πŸ‘‡)

15.07.2025 08:04 β€” πŸ‘ 26    πŸ” 9    πŸ’¬ 0    πŸ“Œ 0

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