Leigh-Ana Rossitto's Avatar

Leigh-Ana Rossitto

@lrossitto.bsky.social

just one brain studying other brains | UCSD BMS phd candidate studying brain metabolism, nutrient signaling, and neurodegen | @mitbrainandcog alum | πŸ‘©πŸ»β€πŸ”¬πŸŒˆ #FirstGen

43 Followers  |  79 Following  |  2 Posts  |  Joined: 08.11.2024  |  1.6452

Latest posts by lrossitto.bsky.social on Bluesky

congrats!!!

12.08.2025 00:44 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Reversible histone deacetylase activity catalyzes lysine acylation - Nature Chemical Biology Tsusaka et al. discover that histone deacetylases, which are well known to remove protein modifications, such as lysine acetylation and Ξ²-hydroxybutyrylation, can also reverse their chemical activity ...

I could not be more excited to have our lab's first story online where we report our discovery that HDACs ~reverse~ their activity to ADD acyl groups to lysine! We found this for our favorite ketone body, BHB, but this pathway controls other lysine modifications too!🧡

www.nature.com/articles/s41...

26.03.2025 14:02 β€” πŸ‘ 124    πŸ” 38    πŸ’¬ 10    πŸ“Œ 4

excited to see this out! congrats to your team!

03.12.2024 19:14 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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