Rubin Lab's Avatar

Rubin Lab

@therubinlab.bsky.social

News from the Rubin Lab 🧬🧫 We conduct DNA-level editing of microbial communities for understanding and control. Managed by lab members. @innovativegenomics.bsky.social @ucberkeleyofficial.bsky.social πŸ”— therubinlab.org

94 Followers  |  67 Following  |  6 Posts  |  Joined: 31.12.2024  |  1.8563

Latest posts by therubinlab.bsky.social on Bluesky

Preview
CRISPR researchers and startup entrepreneurs will share new building in UC Berkeley's Innovation Zone - Berkeley News A planned addition to the campus's Innovation Zone will expand lab space for the Innovative Genomics Institute and build out the largest innovation hub β€” Bakar Labs β€” at any U.S. university.

We’re thrilled to announce IGI–Bakar Labs. This new building will allow the IGI to continue expanding our impact in health and agricultural applications of #CRISPR, and will be shared with the Bakar Labs incubator for growing biotech companies. Learn more: news.berkeley.edu/2025/07/17/c...

17.07.2025 21:05 β€” πŸ‘ 33    πŸ” 18    πŸ’¬ 1    πŸ“Œ 0
Preview
The $20 Million Bet on CRISPR to Cure Rare Childhood Diseases The center will bring custom gene-editing treatments to children.

Out now in TIME β€” @jenniferdoudna.bsky.social on IGI's new initiative, teaming up with the @chanzuckerberg.bsky.social to create a new center for pediatric #CRISPR cures! Read here: ow.ly/E5un50WnbCi

09.07.2025 17:38 β€” πŸ‘ 5    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0
Preview
DOE Announces New Supercomputer Powered by Dell and NVIDIA to Speed Scientific Discovery The NERSC-10 system at Berkeley Lab will accelerate DOE Office of Science research in an era of rapidly advancing simulation, data, and AI capabilities.

✨ Berkeley Lab's @nersc.bsky.social, @delltechnologies.bsky.social, and NVIDIA announce new public-private partnership for game-changing US Dept. of Energy Doudna supercomputer, (NERSC-10, strengthening U.S. capabilities, accelerating discovery, and powering future science. πŸ§ͺ

29.05.2025 22:54 β€” πŸ‘ 32    πŸ” 14    πŸ’¬ 1    πŸ“Œ 2
Preview
Precision gene editing medicine makes history, and it’s just getting started - Nature Biotechnology Despite their astounding success, custom-made base editors and prime editors will need time to broaden their clinical impact.

Precision gene editing medicine makes history, and it’s just getting started www.nature.com/articles/s41...

01.07.2025 14:48 β€” πŸ‘ 6    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
The patient, KJ, reaching out after infusion of the CRISPR therapy, with a big smile! Photo credit Children's Hospital of Philadelphia

The patient, KJ, reaching out after infusion of the CRISPR therapy, with a big smile! Photo credit Children's Hospital of Philadelphia

In a medical breakthrough, a team including IGI’s
@urnov.bsky.social & @giannikopoulosp.bsky.social created an on-demand #CRISPR therapy for an infant with a deadly gene mutation β€” developed, approved, and delivered to the patient in just 6 months.

Read more: ow.ly/G0Bg50VTonC

#RareDisease 🧬

15.05.2025 17:04 β€” πŸ‘ 49    πŸ” 19    πŸ’¬ 0    πŸ“Œ 6
Ben Adler  & Muntathar Jamal Al-Shimary

Ben Adler & Muntathar Jamal Al-Shimary

Phage genomes are full of mysterious proteins that could be harnessed to create new genomic tools. IGI's @doudna-lab.bsky.social & @cresslab.bsky.social with co-first authors @benadler.bsky.social & Muntathar Jamal Al-Shimary detail a new way to exploring phage genomes: ow.ly/uucL50V77n0 πŸ§ͺ🦠🧬

13.03.2025 17:58 β€” πŸ‘ 22    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
Post image

🌟 Big Give is now LIVE! Consider supporting a group of passionate young scientists running experimental teams, training initiatives, and building a synbio community by students FOR students πŸ§‘β€πŸ”¬

bit.ly/igem-give25

#CalBigGive #iGEMBerkeley #bioengineering #syntheticbiology

13.03.2025 06:32 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

The Rubin Lab had an awesome summer hosting Hampton University senior Alex Mendez under the mentorship of @atp-alker.bsky.social and @jayman1466.bsky.social last year. We're excited to see this initiative grow, and thrilled to see more students at IGI labs in the summers ahead! πŸŒŸπŸ§‘β€πŸ”¬

12.03.2025 16:38 β€” πŸ‘ 1    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Jennifer Doudna speaking at Stand Up for Science in Berkeley

Jennifer Doudna speaking at Stand Up for Science in Berkeley

crowd at Stand Up for Science in Berkeley

crowd at Stand Up for Science in Berkeley

crowd at Stand Up for Science in Berkeley

crowd at Stand Up for Science in Berkeley

crowd at Stand Up for Science in Berkeley

crowd at Stand Up for Science in Berkeley

Thanks to out @ucberkeleyofficial.bsky.social community for joining us at Stand Up For Science! @jenniferdoudna.bsky.social spoke about how NIH funding supported her PhD & NSF funding supported her development of #CRISPR genome editing. Federal funding is needed for life-saving science!

08.03.2025 00:03 β€” πŸ‘ 91    πŸ” 28    πŸ’¬ 0    πŸ“Œ 2

At the labs' favorite, Cholita Linda πŸ’

28.02.2025 19:43 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Video thumbnail

Today, the IGI turns 10! We’ve grown from a fledgling initiative focused around developing #CRISPR tools to a full-blown research institute bringing together leaders in basic & translational research! βš•οΈπŸ’ŠπŸŒ±β˜€οΈ

Take a look at our timeline & key achievements from our first decade: ow.ly/GzVt50UTsbP

04.02.2025 17:57 β€” πŸ‘ 19    πŸ” 3    πŸ’¬ 0    πŸ“Œ 4

Fascinating new preprint from @therubinlab.bsky.social out today: "Generating functional plasmid origins with OriGen"
🧬 πŸ–₯️πŸ§ͺ🦠

06.02.2025 19:25 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

This is probably one of the coolest articles I have seen in a while.

Haven't fully grasped it yet , but new improved annotation of plasmid replication apparatuses (very important) AND de novo replication design!

This might improve our understanding of plasmids a lot.

05.02.2025 18:43 β€” πŸ‘ 4    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
Schematic of the OriGen training, generation, and validation pipeline.

Schematic of the OriGen training, generation, and validation pipeline.

We are thrilled to share our latest work: OriGen--the first AI system to generate functional DNA replication sequences! ⬇️

www.biorxiv.org/content/10.1...

06.02.2025 18:31 β€” πŸ‘ 10    πŸ” 3    πŸ’¬ 0    πŸ“Œ 2

🫢

06.02.2025 03:56 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Post image Post image

The Rubin Lab had an amazing new year celebration dinner with @cresslab.bsky.social highlighting lab accomplishments throughout the past year, new members, papers, and our amazing postdoc @aalker.bsky.social's (and soon-to-be assistant professor at University of Rhode Island) birthday!

04.02.2025 00:46 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 0    πŸ“Œ 1
Preview
Research | Rubin Lab

πŸ‘‹ Hello from the Rubin Lab's first post on Bluesky!

Learn more about our research here: therubinlab.org/research

04.02.2025 00:34 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

@therubinlab is following 20 prominent accounts