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Marin Barisic

@barisiclab.bsky.social

studying cell division and cytoskeleton at the Danish Cancer Institute, Copenhagen

919 Followers  |  1,016 Following  |  26 Posts  |  Joined: 23.08.2023  |  2.0132

Latest posts by barisiclab.bsky.social on Bluesky

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Mitosis lovers, get ready for Dubrovnik! πŸ”¬πŸŽ‰
I’m super excited to be organizing the 4th Mitotic Spindle Conference with Nenad Pavin, and we can’t wait to see you there!
Want your abstract to be selected for a talk? Submit by Feb 8!
www.phy.pmf.unizg.hr/~mitosis/
#SpindleCroatia2026

02.02.2026 08:22 β€” πŸ‘ 28    πŸ” 15    πŸ’¬ 1    πŸ“Œ 0
Ad for a postdoc position in centromere biology with colorful chromosomes and centromeres made out of FIMO.

Ad for a postdoc position in centromere biology with colorful chromosomes and centromeres made out of FIMO.

πŸ§ͺ My lab has an opening for a postdoc position soon! Please share/get in touch!

03.02.2026 13:59 β€” πŸ‘ 14    πŸ” 18    πŸ’¬ 0    πŸ“Œ 0
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Mitosis has a timing system. If chromosomes attach properly, cells divide on schedule and keep proliferating. If attachment is slow or incomplete, the delay is recorded β€” and daughter cells stop dividing.
We explore this link in our new preprint.

πŸ”— www.biorxiv.org/content/10.6...

29.01.2026 11:32 β€” πŸ‘ 57    πŸ” 25    πŸ’¬ 1    πŸ“Œ 3
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PhD position in my lab!

28.01.2026 17:25 β€” πŸ‘ 38    πŸ” 36    πŸ’¬ 1    πŸ“Œ 0
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PAF15–PCNA exhaustion governs the strand-specific control of DNA replication Nature - PCNA–PAF15 has a key role in determining replisome dynamics during genome replication and protecting against genome instability.

Dear Colleagues,

Delighted to share that our first lab paper is now published in Nature.!!! 😊😊😊

We identify a previously concealed β€œsafety limit” in DNA replication program: cells intrinsically rate-limit PCNA via PAF15, shaping strand-specific and global replication dynamics.

πŸ‘‰ rdcu.be/e1bBt

29.01.2026 18:30 β€” πŸ‘ 53    πŸ” 21    πŸ’¬ 4    πŸ“Œ 1
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πŸ“£ Please spread: we’re hiring a Lab Manager! It is a critical position in our new lab. As our lab moves to Barcelona and joins the @crg.eu, we’re looking for a Lab Manager to help build the lab and set the lab atmosphere.
πŸ”— Apply here πŸ‘‰ recruitment.crg.eu/content/jobs...

23.01.2026 06:41 β€” πŸ‘ 89    πŸ” 94    πŸ’¬ 2    πŸ“Œ 3
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New preprint from the lab πŸŽ‰: Ξ³-tubulin is a novel target of the tubulin autoregulation pathway! Previously thought to exclusively target Ξ±- and Ξ²-tubulin mRNAs, we show that the TTC5–SCAPER–CNOT11 axis also degrades Ξ³-tubulin mRNA, expanding the scope of this fundamental regulatory mechanism.

10.01.2026 11:17 β€” πŸ‘ 34    πŸ” 14    πŸ’¬ 2    πŸ“Œ 0

Interested in pursuing a PhD by working on a long-neglected marine organism and making a lot of discoveries? Darwin Trust offers a PhD studentship for international students (anyone non-UK) www.findaphd.com/phds/project...

11.11.2025 09:26 β€” πŸ‘ 18    πŸ” 11    πŸ’¬ 0    πŸ“Œ 0
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PhD student position in the Cell Signaling and Cell Cycle group at the Danish Cancer Institute. The Cell Signaling and Cell Cycle group, headed by Prof. Jakob Nilsson, is looking for a highly motivated and enthusiastic PhD student to establish novel CRISPR

I have a PhD opening in my lab for an exiting project using base editor screens to find novel drug targets. Please help spread the word. candidate.hr-manager.net/ApplicationI...

23.10.2025 16:18 β€” πŸ‘ 11    πŸ” 17    πŸ’¬ 0    πŸ“Œ 0
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Polo kinase inhibits protein phosphatase 1 to promote the spindle assembly checkpoint and prevent aneuploidy Protein phosphatase 1 (PP1) is essential for spindle assembly checkpoint (SAC) silencing and mitotic exit, but its regulation during mitosis remains i…

Our latest research in collaboration with @nilssonlab.bsky.social, @andrea-musacchio.bsky.social and Mathieu Bollen reveals a new regulatory strategy employed by cells to control PP1 in mitosis. Check it out in @currentbiology.bsky.social

www.sciencedirect.com/science/arti...

23.10.2025 07:14 β€” πŸ‘ 25    πŸ” 15    πŸ’¬ 5    πŸ“Œ 0
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Are you looking for a PhD? Join us in Barcelona! You'll dive into a community of >100 PhD students from 30 countries exploring the frontiers of biology. You can also join an online workshop on 6 November (15:00 CET) to learn how to find the right lab for you.

More info: www.crg.eu/en/content/t...

23.10.2025 07:55 β€” πŸ‘ 25    πŸ” 28    πŸ’¬ 1    πŸ“Œ 8
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⚑Ready to grow and be inspired as a scientist?

We’re looking for a *PhD student* to join our lab at @crg.eu
in Barcelona and explore how cells self-organize, uncovering life’s inner designπŸ’‘

We offer strong mentoring, cutting-edge science, and a vibrant international team🌍

Check the link below!

23.10.2025 09:56 β€” πŸ‘ 19    πŸ” 16    πŸ’¬ 2    πŸ“Œ 0
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Perspective from Richard McIntosh describing the history of research on #microtubule polymerization in terms of the ideas, technologies, and observations that have emerged as countless researchers have studied the dynamics of these essential cytoskeletal polymers. rupress.org/jcb/article/...

15.10.2025 16:02 β€” πŸ‘ 65    πŸ” 23    πŸ’¬ 3    πŸ“Œ 5
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We hire!
The CytoMorpho Lab is looking for an engineer with a background in cell and molecular biology to join our team in Paris. This is a 18-month contract position, but we're open to exploring long-term opportunities.
More details here:
cytomorpholab.com/index.php/jo...

14.10.2025 13:50 β€” πŸ‘ 83    πŸ” 73    πŸ’¬ 0    πŸ“Œ 0
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See this? This = implanting mouse embryo. Usually this happens inside its mother and is invisible to us, but we can actually watch implantation ex vivo with the hope of understanding why implantation goes awry in embryos of older women. A 🧡...

01.10.2025 18:20 β€” πŸ‘ 223    πŸ” 68    πŸ’¬ 11    πŸ“Œ 18
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New Aurora A kinase role in maintaining proper nuclear shape organization at mitotic exit:
NuMA inhibition causes its dynamic-to-solid material-state transition, leading to bending of segregated mitotic chromosomes
Sachin Kotak @spindlebehavior.bsky.social et al
www.embopress.org/doi/full/10....

19.09.2025 07:49 β€” πŸ‘ 15    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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Computational image analyst (m/f/d) The Max Planck Institute for Molecular Biomedicine in MΓΌnster, Germany, has an opening for a

My lab @mpi-muenster.bsky.social is looking for a computational biologist with a passion for imaging and spatial biology. A staff scientist position with long-term perspective! Apply and spread the word πŸ™ jobs.mpi-muenster.mpg.de/jobposting/0...

12.09.2025 06:17 β€” πŸ‘ 87    πŸ” 86    πŸ’¬ 1    πŸ“Œ 1
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Microtubules: from atoms to complex systems

Microtubules: from atoms to complex systems www.embl.org/about/info/c...

15.09.2025 05:17 β€” πŸ‘ 8    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0
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The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona The kinetochore fibrous corona docks on CENP-E and a second elusive receptor identified as the checkpoint protein BUB1.

The BUB1 and BUBR1 paralogs scaffold the kinetochore fibrous corona | Science Advances www.science.org/doi/10.1126/...

Congratulations @vcmentowski.bsky.social for solving a remarkably challenging molecular puzzle

15.09.2025 04:50 β€” πŸ‘ 59    πŸ” 23    πŸ’¬ 0    πŸ“Œ 1

The kinetochore corona orchestrates chromosome congression through transient microtubule interactions https://www.biorxiv.org/content/10.1101/2025.09.10.675486v1

13.09.2025 08:30 β€” πŸ‘ 3    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

go.bsky.app/KqsM3kd

13.09.2025 07:00 β€” πŸ‘ 16    πŸ” 7    πŸ’¬ 1    πŸ“Œ 0
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Happy to share our work in @embojournal πŸ‘‰ shorturl.at/zXNyn
For decades, we’ve known cells dismantle & rebuild the nuclear envelope in sync with spindle poles. But why does this coordination matter? And how do pole material properties ensure error-free division?
Follow this thread to know more πŸ‘‡

13.09.2025 05:13 β€” πŸ‘ 20    πŸ” 9    πŸ’¬ 4    πŸ“Œ 1
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Chromosome condensation mechanically primes the nucleus for mitosis Timely and accurate transition into mitosis is essential to preserve genome integrity and avoid chromosome segregation errors. This transition depends on spatial and temporal activity patterns of the ...

New preprint from the lab! Please check it out. 🚨
Have you ever wondered how cells decide when it’s time to divide? So did we!
www.biorxiv.org/content/10.1...

03.09.2025 10:08 β€” πŸ‘ 37    πŸ” 13    πŸ’¬ 3    πŸ“Œ 0
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A persistent intracellular bridge and cell cycle misregulation enable polar body cell divisions and tumor formation in Mos-deficient eggs Mammalian female meiosis is uniquely regulated to produce a developmentally competent egg capable of supporting embryogenesis. During meiosis I, homologous chromosomes segregate, with half extruded in...

Check out our new manuscript on biorxiv on the role of MOS in mammalian oocyte meiosis: www.biorxiv.org/cgi/content/...
With @schindlerlab.bsky.social @giselacairobaza.bsky.social @muhammad-haseeb.bsky.social

29.08.2025 17:34 β€” πŸ‘ 26    πŸ” 9    πŸ’¬ 1    πŸ“Œ 1
The balance between B55Ξ± and Greatwall expression levels predicts sensitivity to Greatwall inhibition in cancer cells - Nature Communications The authors develop and characterise a selective Greatwall inhibitor, C-604, and show that its cytotoxicity stems from PP2A-B55Ξ± hyperactivation. They identify B55Ξ± and Greatwall levels as biomarkers…

Excited to share our new @NatureComms paper! We developed C-604, a selective inhibitor of Greatwall kinase, and discovered that cancer cells' sensitivity to it depends on a simple ratio: B55Ξ±/Greatwall expression levels.
www.nature.com/articles/s41...

28.08.2025 11:07 β€” πŸ‘ 15    πŸ” 7    πŸ’¬ 3    πŸ“Œ 0

Is anyone in continental Europe looking for a lab manager? I have a fabulous candidate - let me know and please RT!

25.08.2025 20:03 β€” πŸ‘ 24    πŸ” 31    πŸ’¬ 0    πŸ“Œ 0
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Narozna et al @gorbskylab.bsky.social uncover a high-frequency, chromosome 12-specific mis-segregation error in iPSCs. Eroded 12p arms lead to bridging & micronucleation, enabling widespread trisomy 12. A slight growth advantage allows trisomic cells to persist & dominate rupress.org/jcb/article/...

13.08.2025 17:15 β€” πŸ‘ 9    πŸ” 5    πŸ’¬ 0    πŸ“Œ 0
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The discovery of CENP-A, the centromere-specific histone H3 variant turns 40 years!
Grant Rowley wrote a wonderful historical piece on the cell cycle control of this fascinating piece of chromatin! Check it out.
link.springer.com/article/10.1...

29.07.2025 11:05 β€” πŸ‘ 41    πŸ” 12    πŸ’¬ 1    πŸ“Œ 1
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Geng, @kjverhey1.bsky.social et al find that KIF1C forms condensates where the exposed #kinesin motor domains entangle nearby #microtubules, causing them to bend & break in a process dependent on motor processivity, cluster properties, cytoplasmic viscosity, & MT anchors rupress.org/jcb/article/...

11.08.2025 17:15 β€” πŸ‘ 53    πŸ” 14    πŸ’¬ 2    πŸ“Œ 3

Thanks Adrian!

28.05.2025 06:34 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

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