Mitja M. Zdouc

Great to see it out @georgelund.bsky.social! Congrats!

Ketcher is a good free web-based alternative: lifescience.opensource.epam.com/KetcherDemo/...

Started to use mypy, dropped it again. I had the feeling it introduced more problems than it solved, without making the code more readable

Congrats again @jethrohemmann.bsky.social! I am looking forward to see what kind of interesting chemistry this microbiome may yield @mnd-hki.bsky.social!

It was great having you with us @jorgenavarro.bsky.social! I will miss our discussions on all kinds of biosynthetic gene clusters and on how to improve MIBiG! Good luck with your next projects!

Historia Civilis Civic History.

Also super nice: m.youtube.com/@HistoriaCiv...

Bioinformatics Postdoc at UU/WUR: Map Metabolic Interactions in the Rhizosphere Contribute to plant health and our understanding of the metabolic interactions between microbes and plants in the rhizosphere by computational modelling!

We have an opening for a 4-year postdoc position to study the #rhizosphere #microbiome in @utrechtuniversity.bsky.social @w-u-r.bsky.social, joint project with @marnixmedema.bsky.social in the context of MiCRop. Please tag/forward this to potential candidates and/or repost: www.uu.nl/en/organisat...

Ahaha the other day I saw somebody running metagenome assemblies on our Docker-server. "Why are all our websites so laggy today?" 🤔

Hey Chase yes MIBiG has an automated redirect to the newest version, e.g. mibig.secondarymetabolites.org/go/BGC0000002
I hope that helps!

Lastly, a huge thank you to all participants for their invaluable efforts and trust in MIBiG 4.0. It was a pleasure and an honor to coordinate this community effort! Special thanks to Kai Blin, Nico Louwen, and @marnixmedema.bsky.social for their dedication. (8/8)

Encouraged by the interest of the community, we’ve begun developing a “rolling release” model for MIBiG, where curation happens continuously. Bear with us as we prepare the infrastructure to support this ongoing community effort. (7/8)

We’ve also enhanced the biosynthesis information, including a new option to describe alternative “biosynthetic paths” a BGC can take to produce multiple products. The bioactivity data has undergone a substantial overhaul and now supports quantitative data. (6/8)

What’s new in MIBiG 4.0? We’ve introduced a new review model, where newly submitted or edited entries are checked by volunteer reviewers to ensure high data quality. We’ve also added a “quality” rating based on the comprehensiveness of entries. (5/8)

Over 8 hackathons, 267 contributors made 8304 edits, creating 557 new entries and modifying 590 existing ones. They added 7677 references and linked to new databases like MITE and CyanoMetDB. We estimate that over 4000 person-hours were volunteered! (4/8)

In January 2024, 398 researchers signed up to contribute to MIBiG 4.0 after a call for participation on social media. This overwhelming interest led us to develop a new model for coordinating community involvement. For more details, check out the paper. (3/8)

The MIBiG data standard provides a framework for organizing experimental data on biosynthetic gene clusters (BGCs), making it both human- and machine-readable. Launched in 2015, the MIBiG repository has grown organically and now includes bioactivity and other data as well. (2/8)

MIBiG 4.0: advancing biosynthetic gene cluster curation through global collaboration Abstract. Specialized or secondary metabolites are small molecules of biological origin, often showing potent biological activities with applications in ag

Are you working on natural products? We’ve just released version 4.0 of the MIBiG data standard and repository! It now includes 3059 biosynthetic gene clusters, thanks to the combined efforts of 288 expert contributors. A thread: (1/8) academic.oup.com/nar/advance-...