Vindigni Lab

Will the Senate Save NIH? Rescuing biomedical research is every bit as important as saving Medicaid.

The proposed budget slashes NIH by ~40%, devastating medical research, clinical trials, treatment breakthroughs—life-saving work.

Thousands of lives at risk for tax cuts for the rich? NO THANKS.

Tell your senators to oppose the cuts HERE:
zurl.co/qiKdX


zurl.co/RCR0y
#CutsCostLives

Call your legislators to stop slashing the budget of federal funded research in the “Big Beautiful Bill”. Find numbers @5calls.org

Congratulations Isabelle for winning the Future of Science Fund at the Keystone!! We are very honored to have such a fantastic student in the lab!!!

Congratulations Isabelle for winning the Future of Science Fund at the Keystone!! We are very honored to have such a fantastic student in the lab!!!

Wrapping up an insightful conference on DNA Replication Gaps, Cancer, and Disease! 🎉 Congrats to our Future of Science Fund winners, Larissa Milano and @seppai99.bsky.social! Your achievements inspire us. 🌟 #KSDNARep25 @cantorlab.bsky.social @albertociccia.bsky.social @labvincenzo.bsky.social

Happy to share our DNA Repair special issue on the replication stress response curated with @vindignilab.bsky.social.
www.sciencedirect.com/special-issu...

An interesting collaboration with the @vindignilab.bsky.social on the mechanism of resection at gaps. Spoiler alert: the MRE11 complex acts very differently at gaps vs. at DNA breaks genesdev.cshlp.org/content/earl...

Check out our new paper led by @seppai99.bsky.social from the Vindigni Lab in collaboration with @cejkalab.bsky.social delving into the role of nucleases resecting ssDNA gaps generated by PARPi. You can read more here: genesdev.cshlp.org/content/earl...

Exciting seminar series from Genome integrity italian Network (GiiN), chaired by myself and Raffaella Di Micco! Short talks (2x30’), at convenient time for EU/USA attendees. Big shots and raising stars in an expanding field. See flyers + link to receive email alerts. Please repost to your network!👇

Scientists warn of long-term damage as Trump’s orders slow research By blocking announcements in the Federal Register, the administration is keeping experts from meeting to evaluate funding proposals.

www.washingtonpost.com/science/2025...

this is breaking through
keep up the full court press
* patients harmed right now
* hurts our economy right now
* destroys our STEM infrastructure
* gift to global competitors and adversaries
* dirty tricks by bureaucrats who failed HS chemistry twice

a great way of framing the issue — the bureaucrats are scheming to wreck science they can’t criticize or understand👇🏽

“This really feels like an evil way of using bureaucracy against the process of science, to the contrary of what they say they are doing — streamlining bureaucracy,” Cooper said.

Federal Register Blackout Blocks NIH Funding New strategy is like pouring 'cement in the pipes of the federal funding infrastructure'

Federal Register Blackout Blocks NIH Funding www.medpagetoday.com/special-repo...

The White House found a loophole around the judge’s orders to lift the freeze that will cripple research and scientific discovery for years.

Very important to get this word out!

Trump Cuts Target Next Generation of Scientists and Public Health Leaders A core group of so-called disease detectives, who track outbreaks, was apparently spared. But other young researchers are out of jobs.

Trump Cuts Target Next Generation of Scientists and Public Health Leaders www.nytimes.com/2025/02/18/u...

Trump’s NIH challenges the model that underlies U.S. scientific dominance The 80-year-old partnership between the federal government and research institutions has made the U.S. the leader in scientific innovation. But now a proposed funding cut threatens the arrangement.

www.washingtonpost.com/science/2025...

This campaign needs you now Petition to Reverse the NIH Indirect Cost Cap (NOT-OD-25-068)

Petition to Reverse the NIH Indirect Cost Cap.

Sign and Circulate.
Mobilize. Organize.

chng.it/LS57Nk7r6k

Genetic buffering mechanisms in SNF2-family translocases SNF2-family DNA translocases, a large family of ATPases, have poorly defined roles in genomic stability. In a recent study, Feng et al. identified a synthetic lethal interaction between the SNF2 trans...

Check out our (@vindignilab.bsky.social) Spotlight article highlighting @durocher1.bsky.social group's discovery of synthetic lethal SMARCAL1-FANCM interaction, revealing a novel genetic buffering mechanism for genome stability at simple repeat regions during replication
www.cell.com/trends/genet...

Thank you Petr for hosting me! I had a wonderful time discussing science in Bellinzona!!!

The Vindigni, Krais and @vermalab-washu.bsky.social Labsgiving 2024 featured a full turkey, many laughs and lots of multi-cultural food! 🦃

Thank you!

Thank you!

Finally got on the trend and moved to bluer skies! Though our lab photo got the memo long ago 🧬

Hi Tatiana can you add me to a starter pack? Thanks!

Hi Andrew can you add me to this starter pack? Thanks!