Check out this new review (with animations, natch) of mechanisms of licensing origins of DNA replication - a wonderful (and continuing!) collaboration with Bruce Stillman @cshlnews.bsky.social and John Diffley @crick.ac.uk! www.nature.com/articles/s41...
02.07.2025 17:01 β π 78 π 43 π¬ 6 π 2
Postdoctoral Research Associate in the Blackford Group
A position as Postdoctoral Research Associate is available at the Department of Cellular and Molecular Medicine, in the group headed by Dr. Andrew Blackford. Th
Weβre #hiring, please share! A fully funded #postdoc position is available in my lab to work on DNA damage response mechanisms.
Please get in touch with your CV if you are interested; closing date: 27th June 2025.
More details here: candidate.hr-manager.net/ApplicationI...
29.05.2025 11:26 β π 23 π 35 π¬ 0 π 0
Disabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viability
Losing parental histones during DNA replication fork passage challenges differentiation competence and cell viability.
ππ¨π° ππ¨ πππ₯π₯π¬ π«ππ¦ππ¦πππ« π°π‘π¨ ππ‘ππ² ππ«π πππππ« πππ π«ππ©π₯π’ππππ’π¨π§? Our new study βDisabling leading and lagging strand histone transmission results in parental histones loss and reduced cell plasticity and viabilityβ is out in ππ€πͺπ¦π―π€π¦ ππ₯π·π’π―π€π¦π΄. Led by @lleonie.bsky.social @biranalva.bsky.social π§΅ More belowπ
19.02.2025 19:35 β π 112 π 53 π¬ 5 π 5
DNA replication in primary hepatocytes without the six-subunit ORC
Happy to close 2024 with my last first-author publication from PhD thesis: "DNA replication in primary hepatocytes without the six-subunit #ORC" in @elife.bsky.social. This study challenges existing paradigms in #DNAreplication. π§΅(1/4)
elifesciences.org/reviewed-pre...
01.01.2025 20:57 β π 17 π 7 π¬ 3 π 0
Congrats Chiara π
04.12.2024 20:42 β π 1 π 0 π¬ 1 π 0
Our article "MCM double hexamer loading visualized with human proteins" published in Nature today! βοΈπ¬π§¬ππ₯³
Great collaboration with John Diffley's lab. Congratulations to Florian Weissmann, Julia Greiwe and all other authors!
rdcu.be/d1F7m
27.11.2024 17:24 β π 170 π 44 π¬ 10 π 5
DNA REPAIR/GENOME STABILITY CONFERENCES
New updates to the upcoming DNA repair/Genome Stability conferences over 2024/2025. Please let me know if you have meetings to add:
docs.google.com/spreadsheets...
12.11.2024 04:57 β π 38 π 15 π¬ 2 π 0
Faster and more accurate protein modeling with CryFold. By focusing on nearby points (Local Attention) and employing map masking, CryFold excels in generating models from challenging maps regions. It enables a more cost-efficient model building. π§΅
πΎ github.com/SBQ-1999/Cry...
25.11.2024 17:24 β π 110 π 38 π¬ 1 π 3
Glad to be part of this amazing team! Looking forward to the next science adventure. ππ¬ #Teamwork #Science
25.11.2024 11:18 β π 3 π 0 π¬ 0 π 0
Microbial cell-cell interactions | contractile injection systems | cytoskeleton | evolution | multiscale imaging | ETH ZΓΌrich
- run by lab members -
Est. 1929, JAX is a non-profit scientific research institute specializing in genetics, genomics & mouse models of disease.
USA, Japan, China: https://www.jax.org/
Postdoc π©π½βπ¬π©π½βπ» | Genome Replication&Stability𧬠| Institute of Cancer Research, London π
https://costerlab.com/
32. PhD and Molecular Biologist. Former @FMachinLab and @VSmitsLab member.
Structural biologist working on π₯οΈ protein design, AI, and #CRISPR-Cas gene editing βοΈπ§¬ Avid weirdness connoisseur π©
Study genetic conflicts professionally. Try to avoid conflicts in personal life (with mixed results).
Fred Hutch Basic Sciences
(https://go.bsky.app/ReCeiC6)
UW Genome Sciences (go.bsky.app/L8RAbiJ)
HHMI (hhmi.bsky.social)
Posting in a personal capacity.
Postdoc in the Boulton Lab at the Francis Crick Institute. Currently working on dna damage.
Archaea, Eukaryotes, DNA replication & repair, Evolution enthusiast.
Biochemist, Structural biologist.
Postdoc #UniKiel
Unfocused wildlife πΈ, Smasher ofπΈ. Opinions are my own
Departmental Group Leader - Protein Bioinformatics @ Max Planck Institute for Biology - TΓΌbingen @mpi-bio-fml.bsky.social
Protein evolution // MPI Bioinformatics Toolkit // prokaryotic cell-surface proteins // prokaryotic histones
Senior editor @science.org. Molecular biology, #DNA, #RNA, #gene regulation, #epigenetics, nuclear biology, #chromatin biology, 3D #genome, #synbio, #CRISPR and gene editing, other bacterial immune systems, and #AI in all these
In our lab, hardcore biochemistry meets physics. And coffee. We are investigating DNA replication through single molecule loupe @ Technical University of Munich and MPI of Biochemistry
Assistant Professor of Cell Biology at Harvard Medical School | Nexus of chromatin, transcription, replication, and epigenetics. farnunglab.com
Postdoctoral researcher at UniversitΓ© Paris CitΓ©/CNRS working on computational drug design and MD simulations
Head of Computational Structural Biology Lab @pasteur.fr. ERC-CoG 2022. Research Director DR2 @cnrs.bsky.social. Founder/developer @plumed.org
Geneticist and cell biologist at the University of Southern California | DNA repair | heterochromatin | recombination | nuclear dynamics | nuclear architecture | genome stability.
@DamonRunyon Postdoc Fellow in Tim Springer lab @harvardmed and @BostonChildrens | Organoids, Integrins, Antibodies, CryoEM | @Cornell & @IISERPune alumnus | He/Him
Cellular neurobiologist TIFR India who loves genetics, live imaging and worms. Science is fun, let's go exploring.
Sci comm, write bad poetry, 2 girl mom
lab: https://tinyurl.com/5n7s6ens
https://scholar.google.co.in/citations?user=c4zDSQ8AA