Dr Jacob Scadden

Fig 1: ACT cluster analysis of the nisin O-like BGCs and the B. producta SCSK cluster nucleotide sequences., Scadden et al.

Microbiology’s most read research article of 2025 covers research on the nisin O cluster with a potential for future antimicrobial therapy. Check out the article here: https://doi.org/10.1099/mic.0.001531

🧫 JAMS Sydney is back! 🧫
We’re kicking off 2026 with an Archaea Special 🔬
📅 24 February
⏰ 6–8 pm
📍 Shakespeare Hotel, 200 Devonshire St, Surry Hills
New year, new venue, and a deep dive into one of the most fascinating domains of life.
🎤 Speaker details coming soon — stay tuned!
#JAMSSydney

Registrations for Australia's premier Microbiology conference are now open. www.theasmmeeting.org.au/registration

Thanks to @jamsorgsyd.bsky.social for the opportunity to talk about the evolution of the bacterial flagellar filament to a fantastic crowd. It is always a pleasure to tell this story and showcase the amazing diversity, evolution and adaptation of bacterial flagella! 🦠🔬

Come along and join us at the Keg & Brew for our final monthly of the year! Super keen to hear some amazing talks about all things microbiology🤩🧬

#microbiology #JAMSmicro #science #seminar #networking #biology #research

Structure of a functional archaellum in Bacteria of the Chloroflexota phylum - Nature Microbiology Bona fide gene clusters for archaella are widespread across a bacterial phylum and encode functional motility machinery.

#NewResearch

Structure of a functional archaellum in bacteria of the Chloroflexota phylum

#MicroSky

@archaellum.bsky.social @sshamphavi.bsky.social @loumollat.bsky.social ‬ @mariejoest.bsky.social @sgribaldo.bsky.social

www.nature.com/articles/s41...

Thanks to the @arccoesb.bsky.social for organising a great ECR workshop on grant writing! Some great tips into grant writing and insights into the decision making process. A big thank you to all the panel members for taking time to help during the 1:1 sessions. #ECR #Grant #Academia

Rescue of bacterial motility using two- and three-species FliC chimeras | Journal of Bacteriology Flagellin is a key protein forming the filament of the bacterial flagellar motor which powers most bacterial swimming. Flagellin can have hypervariable domains which can alter motility in different en...

🚨New Paper Alert🚨Our latest paper is published now in the Journal of Bacteriology @asm.org!🦠🔬🏃

A huge thanks to all the co-authors (Matthew Baker, Divyangi Pandit, Pietro Ridone and Yoshiyuki Sowa) for all their hard work! @unswbabs.bsky.social
#flagella #chimera

journals.asm.org/doi/10.1128/...

Out this weekend in @ismepublications.bsky.social

We looked at 10,000 species to map the diversity and history of the bacterial #flagellar motor across the tree of life.

Lots of (re)analysis , especially from Jamiema Sara Philip @unswbabs.bsky.social

academic.oup.com/ismej/advanc...

Mapping the loss of flagellar motility across the tree of life Abstract. Bacterial swimming is mostly powered by the bacterial flagellar motor and the number of proteins involved in the flagellar motor can vary. Quanti

I'm excited to share that our latest research, "Mapping the loss of flagellar motility across the tree of life", in which I was a co-author, has been published in @isme-microbes.bsky.social Journal! 🧪🦠 Huge thanks to all the co-authors!
📖 Read the full paper here: academic.oup.com/ismej/advanc...

The nisin O cluster: species dissemination, candidate leader peptide proteases and the role of regulatory systems Nisin O is an antimicrobial peptide encoded by the human gut bacterium Blautia obeum A2-162 which has antimicrobial activity against clinically relevant organisms. The nisin O biosynthetic gene cluste...

New paper alert! The nisin O biosynthetic gene cluster lacks a leader-peptide cleaving protease but is distributed across different gut-associated genera. @microbiologysociety.org @narbadlab.bsky.social www.microbiologyresearch.org/content/jour...