Amy Lock's Avatar

Amy Lock

@amy-lock.bsky.social

Postdoctoral researcher in Denk lab and Shaw lab. Researching aberrant sensations in keloid scars. stromal cells | single cell sequencing | iPSC sensory neurons | clinical & translational | pain & itch

86 Followers  |  132 Following  |  4 Posts  |  Joined: 18.01.2025  |  1.1484

Latest posts by amy-lock.bsky.social on Bluesky

Preview
Single-cell RNA sequencing clarifies dermal fibroblast subset representation in vitro and reveals variable persistence of keloid disease-associated features In vitro models of scarring and fibrosis are essential to improve our understanding of disease mechanisms and ultimately develop much-needed effective therapeutic strategies. This is particularly true...

Happy to announce our preprint going live on BioRxiv! Interested in whatโ€™s happening to your fibroblastsโ€™ transcriptomic phenotype once itโ€™s in culture? Look no further!

www.biorxiv.org/content/10.1...

@denklab.bsky.social
#fibroblast #scRNAseq #culture #invitro #keloid #ECM #matrix #mesenchymal

20.08.2025 12:22 โ€” ๐Ÿ‘ 7    ๐Ÿ” 3    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Hi everyone! Iโ€™m seeking a new role and would appreciate your support. If you hear of any opportunities, please send me a message! #OpenToWork

About me:
๐Ÿ’ผ Iโ€™m looking for Postdoctoral/Senior Scientist roles.
๐ŸŒ London.
โญ currently work in fibrosis/scarring/pain/itch
โฐ previously worked in biotech

18.04.2025 09:45 โ€” ๐Ÿ‘ 3    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

#FluorescenceFriday testing an ATF3 antibody on newly replated immature iPSC-derived sensory neurons. Never get bored of these beautiful images ๐Ÿ˜ @denklab.bsky.social

07.03.2025 21:44 โ€” ๐Ÿ‘ 11    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Post image

#FluorescenceFriday finally got some keloid scar sections to beautifully show their stromal and sensory neuron architecture! Green = FAP (fibroblasts), white = CD31 (endothelial cells), red = b3-tubulin, blue = DAPI.
@denklab.bsky.social

24.01.2025 18:23 โ€” ๐Ÿ‘ 19    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

@amy-lock is following 20 prominent accounts