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Helen Chen

@hc327.bsky.social

#iPSC scientist & #organoids engineer for #RareDisease working on disease modeling & precision medicine. @StJudeResearch, @ubc alumnusπŸ‡¨πŸ‡¦

121 Followers  |  174 Following  |  2 Posts  |  Joined: 04.12.2024  |  1.4912

Latest posts by hc327.bsky.social on Bluesky

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πŸš€ Exciting MSc opp @ UManitoba! Join 2 interdisciplinary labs (bioinformatics + cancer bio) on a CIHR-funded ovarian cancer project. Gain hands-on training in single-cell genomics & molecular biology. See advertisement to apply #GradResearch #Cancer

26.09.2025 15:31 β€” πŸ‘ 6    πŸ” 7    πŸ’¬ 0    πŸ“Œ 1
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Great talk from @hc327.bsky.social at the 7th annual CCP Phenogenomics Conference! Dr Chen shows how rare disease foundations can really facilitate fantastic scientific progress directly helping patient families!

12.09.2025 14:22 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0
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I still can't get over how cool cells can be reaching out and interacting with one another! This depth shaded membrane marker gives us an idea of how dynamic these extensions can be! #FluorescenceFriday πŸ”¬πŸ§ͺ

15.08.2025 14:21 β€” πŸ‘ 38    πŸ” 6    πŸ’¬ 0    πŸ“Œ 0

Excited to share my latest paper from @stjuderesearch.bsky.social , where we leverage patient derived cortical organoids to study UBA5 associated neurodevelopmental disorders.

07.05.2025 19:26 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Its FINALLY here! The first #FluorescenceFriday πŸ§ͺπŸ”¬out of the Hall lab! We're still in the process of optimizing different fixatives to look for cytonemes and cellular extensions, but a fantastic first time imaging them from Morgan Hiebert!

04.04.2025 21:49 β€” πŸ‘ 25    πŸ” 2    πŸ’¬ 1    πŸ“Œ 0
NIH3T3 cells with a long cytoneme contacting one of the cells to deliver a signal. The SHH ligand is in magenta, the SHH transport protein DISP is in red. Nuclei are blue. Green is the adhesion protein BOC.

NIH3T3 cells with a long cytoneme contacting one of the cells to deliver a signal. The SHH ligand is in magenta, the SHH transport protein DISP is in red. Nuclei are blue. Green is the adhesion protein BOC.

Despite all that is going on, I will not miss a #FluorescenceFriday! ✊ This is a confocal micrograph of a long cytoneme making contact with a recipient NIH3T3 cell (right) to deliver SHH ligand. The 🟣 dots are packages of SHH. Very cool! πŸ”¬ by former postdoc @erichall.bsky.social. πŸ§ͺ #SciArt #DevBio

21.02.2025 16:12 β€” πŸ‘ 58    πŸ” 7    πŸ’¬ 0    πŸ“Œ 0
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Here is an early #FluorescenceFriday post - a 3D render of a developing mouse neural tube showing a signaling filopodium (cytoneme) reaching toward a primary cilium (green) to deliver a cellular signal (SHH, magenta). See alt text for details. Research supported by #NIH #NIGMS πŸ”¬ by Eric Hall. πŸ§ͺ

23.01.2025 20:12 β€” πŸ‘ 62    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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MSc or PhD Student Positions: Cytoneme mediated cell-cell communication in development and disease at Hall Lab

πŸ§ͺπŸ§‘β€πŸ”¬ We are actively recruiting graduate students in the lab right now at UM!
If you are, or know a student looking to do cool research involving cell signaling, development, and πŸ”¬, please share with your networks. For more information, checkout the link below.
rfhs.myjboard.io/jobs/1054626...

21.01.2025 18:34 β€” πŸ‘ 7    πŸ” 9    πŸ’¬ 0    πŸ“Œ 1

Great lab! Great opportunity! Highly recommend!

22.01.2025 00:19 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Lead Researcher / Scientist - Mefford Lab in Memphis, Tennessee | St. Jude Careers St. Jude Careers is hiring a Lead Researcher / Scientist - Mefford Lab in Memphis, Tennessee. Review all of the job details and apply today!

The Mefford Lab is #hiring, come join us! @hcmefford.bsky.social

We have TWO positions open:

(1) *Lead Researcher/Scientist* who will have the opportunity to lead 2D and 3D #epilepsy #genetics modeling to inform better targeted treatments for kids. πŸ§ πŸ§¬πŸ’œ

talent.stjude.org/careers/jobs...

04.12.2024 16:18 β€” πŸ‘ 9    πŸ” 7    πŸ’¬ 1    πŸ“Œ 1

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