Lab on a Chip

Inside front cover of issue 16 of Lab on a Chip. Image: Red and blue vortices swirling together.

On the inside front cover of issue 16 of Lab on a Chip:
Designing enhanced mixing in stagnant microfluidic environments: an artificial cilia approach.
#OpenAccess from Ye Wang et al.
Read now: pubs.rsc.org/en/content/a...

Inside back cover of issue 16 of Lab on a Chip. Image: Electrokinetic DNA extraction in thermal cycler tube.

On the inside back cover of issue 16 of Lab on a Chip:
A three-dimensional microfluidic device embedded within a thermal cycler tube for electrokinetic DNA extraction.
Juan G. Santiago et al @stanford.edu ‬@cornelluniversity.bsky.social‬.
pubs.rsc.org/en/content/a...

PAPER OUT ✨ What if you could use your microscope as a 3D printer? Prototype microfluidics in-house, <5$ in material costs per chip. From idea to experiment within a day. Now published in Lab-on-a-Chip (open-access): doi.org/10.1039/D5LC...

Back cover of issue 16 of Lab on a Chip. Image shows measurement of amyloid beta ratios from patient sample.

On the back cover of issue 16 of Lab on a Chip:
Portable platform for measuring amyloid beta 42/40 ratio via photooxidation-induced fluorescence amplification.
Young Hee Jung, Seok Chung, Yohan Jeong et al.
pubs.rsc.org/en/content/a...

Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology The application of traditional microfabrication techniques to biological research is hindered by their reliance on clean rooms, expensive or toxic materials, and slow iteration cycles. We present an a...

In the latest issue of Lab on a Chip:
Teach your microscope how to print: low-cost and rapid-iteration microfabrication for biology.
#OpenAccess from Olivier Pertz, Lucien Hinderling et al @olivierpertz.bsky.social @lhinderling.bsky.social‬.
Read now: pubs.rsc.org/en/content/a...

Front cover of issue 16 of Lab on a Chip. Image shows three by three grid of transparent domes with coloured balls inside.

On the front cover of issue 16 of Lab on a Chip:
Development of on-chip cell domes using Ca-alginate hydrogel shells for non-adherent cell studies.
#OpenAccess from Shinji Sakai, Satoshi Fujita et al.
Read now: pubs.rsc.org/en/content/a...

Back cover of issue 15 of Lab on a Chip. Image shows cellular blood components swarming over conical substrate.

On the back cover of issue 15 of Lab on a Chip:
Enhancing cancer cell immunocapture on orientation-controlled nanoimprinted microcone arrays in microgap channels.
#OpenAccess from Masumi Yamada et al.
Read now: pubs.rsc.org/en/content/a...

Inside back cover of issue 15 of Lab on a Chip. Image shows a dragonfly wing microfluidic perfusion model.

On the inside back cover of issue 15 of Lab on a Chip:
Insect wing circulation: transient perfusion through a microfluidic dragonfly forewing model.
#OpenAccess from Sangjin Ryu et al
@unlincoln.bsky.social
Read now: pubs.rsc.org/en/content/a...

Inside front cover of issue 15 of Lab on a Chip. Image shows cells self-perfusing through multichamber microfluidic chip.

On the inside front cover of issue 15 of Lab on a Chip:
A novel microfluidic self-perfusion chip (MSPC) for pumpless 3D cell, microtissue and organoid culture.
Shuqi Wang, Bangchuan Hu, Hongwei Jiang et al.
pubs.rsc.org/en/content/a...

Active implantable drug delivery systems: engineering factors, challenges, opportunities Implantable drug delivery systems represent a transformative approach in modern pharmacology, offering precise and controlled drug administration tailored to individual patient needs. By circumventing...

In the latest issue of Lab on a Chip:
Active implantable drug delivery systems: engineering factors, challenges, opportunities.
#OpenAccess from Fabiana Del Bono et al.
Read now: pubs.rsc.org/en/content/a...

Front cover of issue 15 of Lab on a Chip. Image shows measurement of cardiac tissue contractility in response to drugs.

On the front cover of issue 15 of Lab on a Chip:
A polystyrene-film-based device for engineered cardiac tissues enables accurate analysis of drug responses on contractile properties.
#OpenAccess from Yuya Fujiwara, Yoshinori Yoshida et al.
Read now: pubs.rsc.org/en/content/a...

Inside back cover of issue 14 of @labonachip.rsc.org. Per the author, the image represents "In the race for drug testing for NASH, our LEADS model leads the race leaving behind other in vitro models."

On the inside back cover of issue 14 of @labonachip.rsc.org:
LEADS – a comprehensive human liver-on-a-chip for non-alcoholic steatohepatitis (NASH) drug testing.
Hanry Yu et al.
pubs.rsc.org/en/content/a...

Inside front cover of issue 14 of @labonachip.rsc.org. Image shows luminescent sensing of barrier function.

On the inside front cover of issue 14 of @labonachip.rsc.org:
In situ monitoring of barrier function on-chip via automated, non-invasive luminescence sensing.
#OpenAccess from Abigail N. Koppes, Ryan A. Koppes et al.
Read now: pubs.rsc.org/en/content/a...

Back cover of issue 14 of @labonachip.rsc.org. Image shows microbiota from human organs flowing into microfluidic chip.

On the back cover of issue 14 of @labonachip.rsc.org:
Advancements in microfluidic technology for rapid bacterial detection and inflammation-driven diseases.
#OpenAccess from Bee Luan Khoo et al.
Read now: pubs.rsc.org/en/content/a...

Front cover of issue 14 of @labonachip.rsc.org. Image shows a multicoloured tumour growing on microfluidic chip. Cancer-on-a-chip for precision cancer medicine by Weiqiang Chen et al. nyutandon.bsky.social

On the front cover of issue 14 of @labonachip.rsc.org:
Cancer-on-a-chip for precision cancer medicine.
#OpenAccess from Weiqiang Chen et al ‪@nyutandon.bsky.social
Read now: pubs.rsc.org/en/content/a...

Cancer-on-a-chip for precision cancer medicine Many cancer therapies fail in clinical trials despite showing potent efficacy in preclinical studies. One of the key reasons is the adopted preclinical models cannot recapitulate the complex tumor mic...

Engineers at @nyutandon.bsky.social have published a review on human cancer-on-chip platforms used to model the tumor microenvironment. They also explore what’s next for developing next-gen systems to advance precision cancer medicine. 🧪

Read more in @labonachip.rsc.org
doi.org/10.1039/D4LC...

🧪 Professor Jiang’s research focuses on #microfluidics 𝗮𝗻𝗱 𝗴𝗼𝗹𝗱 𝗻𝗮𝗻𝗼𝗽𝗮𝗿𝘁𝗶𝗰𝗹𝗲𝘀 for biomedical analysis – developing analytical tools to manipulate biomolecules and cells for applications in 𝗱𝗶𝗮𝗴𝗻𝗼𝘀𝘁𝗶𝗰𝘀, 𝗽𝗵𝗮𝗿𝗺𝗮𝗰𝗲𝘂𝘁𝗶𝗰𝘀, 𝗳𝗹𝗲𝘅𝗶𝗯𝗹𝗲 𝗲𝗹𝗲𝗰𝘁𝗿𝗼𝗻𝗶𝗰𝘀, 𝗮𝗻𝗱 𝘁𝗶𝘀𝘀𝘂𝗲 𝗿𝗲𝗴𝗲𝗻𝗲𝗿𝗮𝘁𝗶𝗼𝗻.

A huge congratulations to 𝗟𝗮𝗯 𝗼𝗻 𝗮 𝗖𝗵𝗶𝗽 Associate Editor Xingyu Jiang (Southern University of Science and Technology) for winning the Royal Society of Chemistry 2025 Theophilus Redwood Prize! 🏆

📖 Read the full interview and Q&A:

🔗 www.rsc.org/standards-an...

Available to read as open access in @labonachip.rsc.org.
pubs.rsc.org/en/content/a...
@mimetas.bsky.social

Inside back cover of issue 13 of @labonachip.rsc.org. Image shows molecules changing colour across spectrum of pH.

On the inside back cover of issue 13 of @labonachip.rsc.org:
Halochromism of rosolic acid: a pH-sensitive colorimetric dye combined with a smartphone technique for quantification of DNA in molecular diagnostics.
Nae Yoon Lee et al.
pubs.rsc.org/en/content/a...

Inside front cover of issue 13 of @labonachip.rsc.org. Image shows rock-based pore structure embedded on microfluidic chip.

On the inside front cover of issue 13 of @labonachip.rsc.org:
Rock-on-a-chip: a novel method for designing representative microfluidic platforms based on real rock structures and pore network modelling.
#OpenAccess from Saman A. Aryana et al.
Read now: pubs.rsc.org/en/content/a...

Back cover of issue 13 of @labonachip.rsc.org. Image shows immunosensing of blood analytes.

On the back cover of issue 13 of @labonachip.rsc.org:
A membrane-based immunosensor enabling high antifouling performance and sensitive molecular recognition.
Takeo Yamaguchi et al.
pubs.rsc.org/en/content/a...

Front cover of issue 13 of @labonachip.rsc.org. Image shows Finger-actuated rotating fluid control mechanism for sweat sampling.

On the front cover of issue 13 of @labonachip.rsc.org:
A novel manual rotating fluid control mechanism in a microfluidic device with a finger-actuated pump for dual-mode sweat sampling.
Zedong Nie et al.
pubs.rsc.org/en/content/a...

3D-printed micro-pore evaporator for increasing concentration of analytes in aqueous solutions To address the detection limit challenges of analytical instruments at low concentrations, this study explores the development of a concentrator, fabricated via micro-3D printing technology, relying o...

In the latest issue of @labonachip.rsc.org:
3D-printed micro-pore evaporator for increasing concentration of analytes in aqueous solutions.
#OpenAccess from Tanya Hutter & Yufeng Su @utmechanical.bsky.social.
Read now: pubs.rsc.org/en/content/a...

A compartmentalization-free microfluidic digital assay for detecting picogram levels of protein analytes Digitalizing the signals generated from single protein molecules has significantly improved the sensitivity of immunoassays compared to traditional analog “bulk” measurements. The single molecule arra...

Publication Alert🚨: Check out our recent paper in @labonachip.rsc.org A compartmentalization-free microfluidic digital assay for detecting picogram levels of protein analytes
pubs.rsc.org/en/content/a...

A gut–brain axis on-a-chip platform for drug testing challenged with donepezil Current drug development pipelines are time-consuming and prone to a significant percentage of failure, partially due to the limited availability of advanced human preclinical models able to better re...

Fanizza et al. developed PEGASO, a gut-brain axis-on-a-chip platform for drug screening & personalized medicine. The team modeled the physiological passage of AD drug #donepezil in the new system. Check out the paper in @labonachip.rsc.org

pubs.rsc.org/en/content/a...

Deciphering the unique inertial focusing behavior of sperm cells Inertial focusing has been utilized to advance assisted reproductive technologies (ART) for animal breeding and in vitro fertilization (IVF) by separating sperm cells from biofluids with complex cell ...

In the latest issue of @labonachip.rsc.org:
Deciphering the unique inertial focusing behavior of sperm cells.
#OpenAccess from Ian Papautsky, Zhangli Peng et al.
Read now: pubs.rsc.org/en/content/a...

☝️ @aniruddh.bsky.social‬ @gatechengineers.bsky.social

Inside front cover of issue 12 of @labonachip.rsc.org. Image shows antibody detection from blood sample on reconfigurable microfluidic platform.

On the inside front cover of issue 12 of @labonachip.rsc.org:
Sample-sparing multiplexed antibody Fc biomarker discovery using a reconfigurable integrated microfluidic platform.
#OpenAccess from Aniruddh Sarkar et al.‪
Read here: pubs.rsc.org/en/content/a...

Back cover of issue 12 of @labonachip.rsc.org. Image shows a drug being screened through sequential organoid on a chip system.

On the back cover of issue 12 of @labonachip.rsc.org:
Microfluidic organoid-slice-on-a-chip system for studying anti-cholangiocarcinoma drug efficacy and hepatorenal toxicity.
Bangchuan Hu, Haijie Hu, Shuqi Wang et al.
pubs.rsc.org/en/content/a...