Valentin Flury

nanodiag BW receives funding for second implementation phase - nanodiag BW Nanopore technology for next-generation molecular diagnostics: Freiburg innovation network continues development toward clinical application

Fantastic news before we enter the weekend. @nanodiagbw.bsky.social receives funding approval!

The »cluster4future« receives 15 Mio. € for their next phase making nanopore technology usable for the molecular diagnostics. Great success.

Our proteomics facility is part of the cluster. 😍

PAF15–PCNA exhaustion governs the strand-specific control of DNA replication Nature - PCNA–PAF15 has a key role in determining replisome dynamics during genome replication and protecting against genome instability.

Dear Colleagues,

Delighted to share that our first lab paper is now published in Nature.!!! 😊😊😊

We identify a previously concealed “safety limit” in DNA replication program: cells intrinsically rate-limit PCNA via PAF15, shaping strand-specific and global replication dynamics.

👉 rdcu.be/e1bBt

A picture of current members of the Groth lab

Congratulations to @groth-anja.bsky.social on receiving the Novo Nordisk Foundation Jacobæus Prize 🏆 we’re proud to see Anja's mentorship, leadership, & pioneering work in epigenetic cell memory getting top recognition 👏 celebrating the contributions of past & present lab members to this work too 🥳

Fully-funded #PhD positions in #epigenetics, #biophysics & #metabolism, gene regulation, cell biology and more…

Are you already on track to start an exciting research career @maxplanck.de & @uni-freiburg.de?

This is your timeline. Apply by February 6th, 2026
www.ie-freiburg.mpg.de/apply-imprs-...

Read in Nature: nature.com/articles/s41586-025-09899-8

Stress controls epigenetic inheritance!

A histone ubiquitylation-based regulatory hub links stress/environmental signaling to heterochromatin self-propagation and epigenetic inheritance-reshaping how we think about development, drug resistance, and cancer
👉 nature.com/articles/s41586-025-09899-8

Happy New Year!🎉 We hope everyone has enjoyed the holidays! If you have an exciting chromatin/transcription story, or if you know someone with one, please fill out the form or get in contact with us! 😉
forms.gle/TBi38UgYxPAB...

Still time to apply until January, 19th!

Congrats to the team for such creative craft - first time winner of the Christmas Wreath-Off at @mpi-ie.bsky.social!🥳

Happy holidays from the @flurylab.bsky.social!🎉 A year with a lot of firsts: first PhD students, first Postdoc, first grant & first farewells - and a first lab move, too! Thanks to my amazing team for the hard work & curiosity!💪🧐👥 Can't wait to tackle more firsts (& seconds) in the coming year(s)!🙌🤩

Poster calling for applications for fully funded Max Planck PhD positions in Freiburg, Germany, listing research areas and benefits, deadline February 6, 2026.

Our PhD program IMPRS-EBM of #Epigenetics, #Biophysics & #Metabolism will open for applications next week. 📢

Want to work at the forefront of epigenetic research at an MPI? Looking for a fully-funded #PhDposition at Max Planck? Here is your chance: www.ie-freiburg.mpg.de/IMPRS-PhD-Pr...

Awesome, big congratulations!!🎉

Seminarankündigung des Max-Planck-Instituts Freiburg mit Thema zur DNA-Sequenz und Chromatin, Datum, Uhrzeit und Ort, Porträt von Philipp Korber. MPS: Philipp Korber - The role of DNA sequence, chromatin remodelers, barriers and their intrinsically disordered regions in nucleosome positioning Max Planck Seminar DATE: Nov 20, 2025 TIME: 01:00 PM SPEAKER: Philipp Korber AFFILIATION: Biomedical Center (BMC) of LMU Munich, Germany LOCATION: MPI-IE ROOM: Lecture Hall HOST: Nicola Iovino

This Thursday, we’re pleased to welcome Philipp Korber.
Prof Korber leads a research group on “Nucleosome Positioning & Remodeling in Yeasts” at the @bmc-lmu.bsky.social in Munich. His work has identified ATP-dependent chromatin remodelers as major determinants of nucleosome positioning.

Join us!

Congrats Susi! Amazing work!👏👏👏

Wonderful opportunity to work with Martin Howard and my group trying to understand how chromatin influences gene transcription and expression. Integration of theory, modelling, and experimentation. Come and join the team!
Please repost!

jobs.jic.ac.uk/Details.asp?...

Very sad news, John Gurdon has died.

A developmental biologist's developmental biologist, Nobel prize winner

His work is the foundation of much of today's dev & stem cell bio.

An inspiration to many, including me. Always asking questions & wanting the answers

www.magd.cam.ac.uk/news/profess...

It has been a lot of fun to present our research focus and get to know the @gfgenetik.bsky.social! Thank you so much for having me and organising this great symposium! Looking forward to the next one!

Discrete Subdomains Establish Epigenetic Diversity in Subtelomeric Heterochromatin Subtelomeres are imperfect repeats adjacent to telomeres that are repressed by heterochromatin. Although essential for genome integrity, their repetitive nature has thwarted dissection of local hetero...

This one feels special: our latest work on subtelomeric heterochromatin is now on www.biorxiv.org/content/10.1....
This story was driven by the virtuoso PhD work of Agnisrota Mazumder @agnisrota.bsky.social, co-mentored with @al-sadylab.bsky.social, and grew out of our #MSCA Cell2Cell network.

🚀 Our new paper is out @natmethods.nature.com!

Kuffer & Marzilli engineered conditionally stable MS2 & PP7 coat proteins (dMCP & dPCP) that degrade unless bound to RNA, enabling ultra–low-background, single-mRNA imaging in live cells.

🔗 www.nature.com/articles/s41...
🧬 www.addgene.org/John_Ngo/

Congrats to everyone involved! 👏👏👏 Can’t wait to dig into this exciting piece of work!🤩

I am excited to announce that we are looking for a Lab Manager @fmiscience.bsky.social in Basel. If you want to be part of a growing team investigating development and tissue formation, and are enthusiastic about helping set up a new lab, please check out the role:

www.fmi.ch/education-ca...

We are hiring-join us!

Thanks a lot Kinga! We will!🤩

Grazie Chiara!

Thanks Nezha!

Thanks a lot @cibss.bsky.social !Looking forward to exciting endeavours together😀

Thanks Paula! Hope all is well😀

Thanks Francesca! Exciting adventures ahead😍♻️

Thanks a lot Rob!

Thanks! See you soon!🥳

Thanks Sandra, looking forward to the upcoming meeting!