Real-time, multi-pathogen wastewater genomic surveillance with Freyja 2
Case-based infectious disease surveillance is fundamental to public health, but is resource-intensive, logistically complex, and prone to sampling bias. Wastewater testing and sequencing have increasi...
A few days ago we preprinted our Freyja 2 paper, describing the expansion of our original Freyja method to a real-time, multi-pathogen surveillance tool to track pathogen lineage prevalence and dynamics from sequencing of wastewater and other complex samples (like milk). 🧵
doi.org/10.1101/2025...
31.07.2025 19:16 — 👍 32 🔁 9 💬 1 📌 0
The title of the paper: "A minimum data standard for wildlife disease research and surveillance" - and an example data table
NEW! 🎉 We need wildlife disease surveillance to predict epidemics, but data sharing is rare - we found that only 2-3% of studies share raw data. So, we spent three years developing a data standard and R package to help get wildlife disease data into FAIR repositories. www.nature.com/articles/s41...
21.06.2025 15:17 — 👍 130 🔁 49 💬 3 📌 4
Top panels: graphs showing increases in spillover events, extinction rates, and temperature anomalies over the last few centuries. Bottom panel: a map of 10 pandemics since the year 1900. Four were linked to agriculture, two to wildlife use, and one to climate change.
🚨😷🧪 NEW: A growing body of evidence shows that pandemics, biodiversity loss, and climate change are part of a broader polycrisis - but there are no simple solutions. A sweeping overview of "Pathogens and planetary change" for the first issue of @natrevbiodiv.bsky.social, out now 🔓 rdcu.be/d6lHl
15.01.2025 14:16 — 👍 543 🔁 227 💬 17 📌 19
