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SFB Targeted Protein Degradation

@sfb-tpd-vienna.bsky.social

FWF-funded Austrian Research Consortium of the labs of Sascha Martens, Alwin KΓΆhler, Andreas Bachmair, Gijs Versteeg, Tim Clausen, David Haselbach, Yasin Dagdas, Silvia Ramundo, Georg Winter, Christian Becker & Ilaria Piazza. www.protein-degradation.org

735 Followers  |  264 Following  |  66 Posts  |  Joined: 08.03.2024  |  2.0922

Latest posts by sfb-tpd-vienna.bsky.social on Bluesky

Ready to launchπŸš€ your own lab? @maxperutzlabs.bsky.social are looking for a #tenure-track Assistant ProfessorπŸ‘‡πŸ‘‡ Supportive, collaborative institute embedded @viennabiocenter.bsky.social with strong infrastructure and excellent training programs.
πŸ”— www.maxperutzlabs.ac.at/news/open-po...

29.07.2025 08:31 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

πŸš€Great work led by @elias-adriaenssens.bsky.social in the Martens lab @maxperutzlabs.bsky.social shows a new mechanism for #mitophagy initiation, revealing unexpected flexibility in the assembly& activation of the #autophagy machineryπŸ‘‡
Check it out πŸ”— www.nature.com/articles/s41...

25.07.2025 15:26 β€” πŸ‘ 9    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

Exciting findings, out now @natcellbio.nature.com πŸ‘‡πŸ‘‡
Congratulations Elias & all co-authors!

25.07.2025 15:22 β€” πŸ‘ 2    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

❗Exciting #PhD opportunity in the Piazza Lab πŸ‘‡ @iplab.bsky.social @scilifelab.se

#PhDPosition πŸ§ͺπŸ§‘β€πŸ”¬

22.07.2025 08:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

πŸ“£Exciting opportunity at @maxperutzlabs.bsky.social πŸ‘‡
A great chance to join an outstanding research environment, based at campus @viennabiocenter.bsky.social Spread the word or apply!
πŸ†• #professorship #Professur
πŸ”— www.maxperutzlabs.ac.at/fileadmin/us...

08.07.2025 14:40 β€” πŸ‘ 2    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Full Professorship in Molecular Mechanisms of Disease - Vienna BioCenter, Austria job with Max Perutz Labs, University of Vienna | 12841053 Join theMax Perutz Labs as Full Professor to unravel disease mechanismsβ€”from metabolism and stress to RNA regulation, epigenetics, and immunity.

Exciting and rare opportunity to join the @maxperutzlabs.bsky.social and the @viennabiocenter.bsky.social as a Full Professor!
www.nature.com/naturecareer...

02.07.2025 07:18 β€” πŸ‘ 35    πŸ” 29    πŸ’¬ 0    πŸ“Œ 2
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The @viennabiocenter.bsky.social PostDoc Program call is now open! We have 16 fully-funded positions for scientists with a PhD in biology, chemistry, physics, bioinformatics etc.

Apply here: training.vbc.ac.at/post-docs/vi...

#VBCPostDoc

02.06.2025 11:28 β€” πŸ‘ 36    πŸ” 22    πŸ’¬ 2    πŸ“Œ 1
VIPΒ³ Post Doc Program (2025 - 2030) VIP3 is a postdoctoral fellowship program at the Vienna BioCenter offering three – year fellowships that are open to candidates with backgrounds in life sciences, chemistry, physics, medicine, enginee...

postdoc opening in vienna: study lipid droplets (LDs) with integrative structural biology, uncover how LD proteins shuttle between cytosol & nucleus to regulate lipid metabolism, organelle architecture and immune response. #VIP3 #lipidtime #cryoEM #coffee training.vbc.ac.at/post-docs/vi...

24.06.2025 21:03 β€” πŸ‘ 10    πŸ” 11    πŸ’¬ 0    πŸ“Œ 2
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πŸ‘€ Did you know?

The Vienna BioCenter offers an English speaking life science community in the most livable city in the world!

Want to be part of it?

The VIPΒ³ PostDoc Program call is open – apply now for this unique opportunity! training.vbc.ac.at/post-docs/vi...

#VBCPostDoc

23.06.2025 07:16 β€” πŸ‘ 8    πŸ” 6    πŸ’¬ 1    πŸ“Œ 1

πŸ‘ Big CONGRATS to @sramundo.bsky.social for receiving an FWF @fwf-at.bsky.social ASTRA Award 🌠✨
See all about it πŸ‘‡

02.07.2025 14:46 β€” πŸ‘ 3    πŸ” 3    πŸ’¬ 0    πŸ“Œ 0

Excellent news ✨Congratulations to Alwin KΓΆhler πŸ‘πŸ‘πŸ‘@maxperutzlabs.bsky.social
See ➑️ www.maxperutzlabs.ac.at/news/latest-...

23.06.2025 15:09 β€” πŸ‘ 10    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

πŸ™Thank you for joining!

29.05.2025 19:42 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Last but not least, THANKS to our awesome #ubfriends2025 organizing team πŸ™Œ – these brilliant✨ #ECRs:
@lilliebell.bsky.social(Clausen lab)
Milica Mihailovic (KaragΓΆz lab)
@berndbauer.bsky.social (Martens lab)
Chrysanthi Kagiou (Winter lab)
@carlabrillada.bsky.social & Xavier St John (Ramundo lab)

13.05.2025 21:03 β€” πŸ‘ 8    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Thank you for coming! And CONGRATS for presenting one of the BEST POSTERS πŸ…πŸ‘

13.05.2025 16:28 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Thank you for coming! It was great having you here ☺️
And congrats again for the Best Short Talk πŸ†

13.05.2025 16:26 β€” πŸ‘ 15    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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…and the #ubfriends2025 Travel Grants go to:

@emmafink.bsky.social (Dana-Farber Cancer Institute)
Eirini Kalogerakou (Univ. of Helsinki)
Leah Erwin (Univ. College Cork)
Julia Chastel (Univ. of Montreal)
Tom Eisenack (Univ. of Cologne)
Amy Ponsford (Univ. of Liverpool)
Mathilde Vincent (ETH Zurich)

13.05.2025 16:22 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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...AND THE #ubfriends2025 WINNERS ARE πŸ‘

Best Short Talk:
@leokiss.bsky.social (@mpibiochem.bsky.social)

Best Posters:
Irene Schwartz (lab of @versteegga.bsky.social),
@julianvangerwen.bsky.social (@imsb-eth.bsky.social),
Tom Eisenack (lab @trentini-lab.bsky.social), and
@berndbauer.bsky.social!

13.05.2025 16:12 β€” πŸ‘ 4    πŸ” 1    πŸ’¬ 1    πŸ“Œ 2

Thanks to our supporters & sponsors @maxperutzlabs.bsky.social, @impvienna.bsky.social, @imbavienna.bsky.social, @gmivienna.bsky.social, @cemm-vienna.bsky.social, @promegagermany.bsky.social & MedChemExpress, we had Travel Grants, Poster Prizes & a Best Short Talk Prize to awardπŸ†
Award winners 🧡⏬

13.05.2025 15:52 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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A special THANK YOU to our fantastic guest speakers #ubfriends2025!
@delladavid-lab.bsky.social, Virginia De Cesare, Judith Frydman, Manu Hegde, @landerlab.bsky.social, @andrea-musacchio.bsky.social, @thewittysquare.bsky.social, Hidde Ploegh, @spoel-lab.bsky.social & Sylvie Urbe!

13.05.2025 15:21 β€” πŸ‘ 7    πŸ” 0    πŸ’¬ 3    πŸ“Œ 0
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After all the (re-)connections on day 1, day 2 of #ubfriends2025 even more fabulous for us 🀩
BIG THANKS to all the speakers & poster presenters for sharing their exciting research, and to EVERYONE who joined us!
It was a true pleasure to host this amazing communityπŸ‘‡

13.05.2025 14:55 β€” πŸ‘ 24    πŸ” 5    πŸ’¬ 1    πŸ“Œ 2
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...and we ended the day on a cozy note in a traditional Viennese Heurigen πŸ‡πŸ· on the outskirts of Vienna #ubfriends2025

09.05.2025 11:15 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Day 1 one #ubfriends2025 was full of great 🎀talks, creative elevator pitches, lively poster sessions and stimulating discussions...

09.05.2025 11:15 β€” πŸ‘ 11    πŸ” 3    πŸ’¬ 1    πŸ“Œ 0
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@martenslab.bsky.social kicking off the #ubiquitin&friends symposium @sfb-tpd-vienna.bsky.social

08.05.2025 07:04 β€” πŸ‘ 22    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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...starting with the first Guest Talk by the one and only Manu Hegde @mrclmb.bsky.social
#ubfriends2025

08.05.2025 07:27 β€” πŸ‘ 8    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
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Ready & EXCITED to kick off two exciting days of #Ubiquitin & Friends! #ubfriends2025

08.05.2025 07:24 β€” πŸ‘ 17    πŸ” 2    πŸ’¬ 1    πŸ“Œ 2
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πŸ“‘ New study! Why would cells invest in a protein that degrades within minutes? TRIM52 is one of the most unstable proteins in the human proteome. Research by @versteegga.bsky.social in Nature Communications reveals its advantageous role ➑️ tinyurl.com/yw6wtzkc

@univie.ac.at
@meduniwien.ac.at

29.04.2025 13:04 β€” πŸ‘ 13    πŸ” 4    πŸ’¬ 0    πŸ“Œ 0

πŸ†•publication from the @versteegga.bsky.social labπŸ‘
1st author Alexandra Shulkina & coauthors (incl. collab with @clausenlab.bsky.social also in our SFB) identified the functional role of TRIM52 in maintaining genome stability, and unravelled how one of the most unstable human proteins is degradedπŸ‘‡

02.05.2025 08:58 β€” πŸ‘ 4    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
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Structural basis for the ubiquitin chain recognition of the human 26S proteasome Proteasomal degradation is a fundamental process for all eukaryotic life. A protein destined for degradation is first tagged with a polyubiquitin chain, which is selected by the proteasome. Different ...

New Preprint: We have solved the structure of the proteasome in complex with two different ubiquitin chains: www.biorxiv.org/content/10.1... This work is spearheaded by PhD Student Sascha Amann
Let me walk you through it 🧡 1/9

09.04.2025 08:59 β€” πŸ‘ 74    πŸ” 25    πŸ’¬ 2    πŸ“Œ 3
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How do cells decide on the life or death of a protein?

πŸ”¬ Researchers around @haselbachlab.bsky.social at the IMP have captured the first high-resolution view of the human proteasome reading different ubiquitin signals.

➑️Read the full story: imp.ac.at/news/article...

09.04.2025 09:11 β€” πŸ‘ 28    πŸ” 9    πŸ’¬ 1    πŸ“Œ 0

Can't wait for this years Ubiquitin & Friends in Vienna! Still time to register until Monday ;-)

04.04.2025 12:48 β€” πŸ‘ 9    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

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