Tycho Mevissen's Avatar

Tycho Mevissen

@tychomevissen.bsky.social

Postdoc in Johannes Walter's lab at Harvard Medical School. Interested in transcription, DNA repair, and ubiquitin. Formerly @MRC_LMB in David Komander's lab.

681 Followers  |  245 Following  |  3 Posts  |  Joined: 13.11.2024  |  1.4645

Latest posts by tychomevissen.bsky.social on Bluesky

Graphical abstract for one of the papers

Graphical abstract for one of the papers

Graphical abstract for one of the papers

Graphical abstract for one of the papers

Graphical abstract for one of the papers

Graphical abstract for one of the papers

STK19
Transcription coupled repair
With TFIIH

#ChromatinHaiku
www.cell.com/cell/fulltex...
www.cell.com/cell/fulltex...
www.cell.com/molecular-ce...

15.11.2024 14:46 β€” πŸ‘ 37    πŸ” 10    πŸ’¬ 1    πŸ“Œ 0

Thank you, Ben!

20.11.2024 22:45 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Also check out related studies on STK19 by the labs of Martijn Luijsterburg/Jesper Svejstrup, Jurgen Marteijn/Titia Sixma, and Jinchuan Hu, respectively:

➑️ cell.com/cell/fulltex...
➑️ cell.com/molecular-ce...
➑️ academic.oup.com/nar/advance-...

14.11.2024 16:43 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
Preview
STK19 positions TFIIH for cell-free transcription-coupled DNA repair Together with structural analyses, a cell-free system for transcription-coupled nucleotide excision repair (TC-NER) shows that STK19 is an integral component of the TC-NER complex that couples RNA pol...

Let's get this site started. I'm excited to share that our work on transcription-coupled DNA repair is now published! We recapitulated TC-NER in Xenopus egg extract and identified STK19 as a core repair factor that couples lesion-stalled RNA Pol II to TFIIH. 🧬🐸

➑️ cell.com/cell/fulltex...

14.11.2024 16:18 β€” πŸ‘ 35    πŸ” 10    πŸ’¬ 7    πŸ“Œ 2

@tychomevissen is following 20 prominent accounts