A big thank you to all authors, especially Marius Halliez and Laure Strochlic for their incredible contributions to this project!
01.07.2025 17:21 — 👍 0 🔁 0 💬 0 📌 0
Our collaborators showed that passive transfer of anti-MuSK CRD antibodies in mice induced hallmark features of #myastheniagravis (MG), providing the 1st evidence of the MuSK CRD domain’s involvement in MG pathogenesis and advancing our understanding of its underlying pathophysiological mechanisms.
01.07.2025 17:21 — 👍 0 🔁 0 💬 1 📌 0
As part of our team in @neuromagendie.bsky.social – INSERM U1215 and the Bioprot Platform in @neurobordeaux.bsky.social , we designed and carried out the purification of the MuSK CRD peptide, a key step that enabled the successful production of rabbit anti-MuSK CRD antibodies.
01.07.2025 17:21 — 👍 0 🔁 0 💬 1 📌 0
JCI -
MuSK cysteine-rich domain antibodies are pathogenic in a mouse model of autoimmune myasthenia gravis
I'm thrilled to share our contribution in a collaborative work with Laure Strochlic ‘s team, that is now published in the Journal of Clinical Investigation!
www.jci.org/articles/vie...
01.07.2025 17:21 — 👍 1 🔁 1 💬 1 📌 0
Beautiful periodicity!
26.05.2025 17:53 — 👍 1 🔁 0 💬 0 📌 0
BBs?
05.04.2025 09:38 — 👍 1 🔁 0 💬 1 📌 0
Thrilled to host the #Syncell Inc #Microscoop event on March 21st in #Bordeaux!
Anybody interested in the prospects of #spatialproteomics is more than welcome!
📍 **Location:** Amphi Broca Nouvelle Aquitaine, Bordeaux
📅 **When :** March 21st, 2:00pm-3:30pm
03.03.2025 07:05 — 👍 1 🔁 1 💬 0 📌 0
PhosX: data-driven kinase activity inference from phosphoproteomics experiments
AbstractSummary. The inference of kinase activity from phosphoproteomics data can point to causal mechanisms driving signalling processes and potential dru
Kinases play a role in many diseases, making them prime targets for therapeutic intervention.
Enter PhosX, a new tool transforming the way researchers analyse and interpret kinase activity.
Read the full article: academic.oup.com/bioinformati...
@alussana.bsky.social @epetsalaki.bsky.social
27.01.2025 11:56 — 👍 21 🔁 14 💬 1 📌 2
already a must read. The latest about the #axoninitialsegment !
16.02.2025 07:46 — 👍 2 🔁 1 💬 0 📌 0
The Martin lab has an open postdoc position at the interface of #cytoskeleton and #condensate biology, in a fantastic research community!
If interested, do not hesitate to contact us: mocel.unige.ch/research-gro...
Please RT!
23.10.2024 16:24 — 👍 9 🔁 13 💬 0 📌 0
Cool paper (and great resource). I’m especially keen the disconnect between mRNA and protein levels in adult tissues! Pay attention #devbiol, it’ll be the same in embryonic tissues.
www.cell.com/cell/fulltex...
08.01.2025 13:06 — 👍 34 🔁 10 💬 0 📌 2
Cartoon of the mechanism from the last figure of Thyagarajan et al.
A neuronal Rube Goldberg machine 🤯
Wnt from surrounding cells is internalized via clathrin-coated pits at dendritic branch points before triggering microtubule nucleation at the surface of endosomes. Great work from Melissa Rolls' lab in @plosbiology.org: journals.plos.org/plosbiology/...
08.01.2025 21:54 — 👍 36 🔁 13 💬 1 📌 0
nice dice set!
23.12.2024 06:40 — 👍 1 🔁 0 💬 1 📌 0
at least, the "massues" are not on fire!
18.12.2024 04:50 — 👍 0 🔁 0 💬 1 📌 0
I wish I had this a few years back!
10.12.2024 21:26 — 👍 1 🔁 0 💬 1 📌 0
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Signal Transduction and Targeted Therapy (STTT) | A Nature Portfolio journal | Impact Factor 52.7 | Q1 in Biochemistry, Cell Biology & Molecular Medicine | Open Access
Visit: https://www.nature.com/sigtrans/
International Open Access journal publishing on molecular and translational medicine. IF 2024,9.4; Scopus Citescore 2024, 8.4.
Cilia | Disease Mechanism | Imaging | Genomics| Obesity| Gut-health| Microtubules| Kidney. MRC-Edinburgh & ESRIC-Imaging-UK| EMBLHeidelberg & Max Plank-Germany| UMass Medical School-USA| NII-India Alum
Neuroscience PhD Candidate at Baylor College of Medicine | Rasband Lab | Nodes of Ranvier and AIS enthusiast
Assistant Professor at the University of South Carolina. Focusing on the axon initial segment and Chandelier cells. AAV, CRISPR, Proteomics.
Decoding how the gut thinks 🦠🪱🧠💪
Neuroscientist with interests in
#EnergyMetabolism #EntericNeurons #Fats
@crick.ac.uk @institutducerveau.bsky.social
Executive Editor, Journal of Clinical Investigation & JCI Insight
The JCI is a premiere venue for discoveries in basic and clinical biomedical science that will advance the practice of medicine. Est. 1924
Post doc in ICVS (Ana João Rodrigues team) Braga Portugal, alumni MarsicanoLab Bordeaux France
Postdoc at the Institute of Philosophy, Zagreb | PhD, King’s College London | Primarily working on mind and metaphysics 💭
Bioinformatics Scientist / Next Generation Sequencing, Single Cell and Spatial Biology, Next Generation Proteomics, Liquid Biopsy, SynBio, AI/ML in biotech // http://albertvilella.substack.com
Neuroscientist at the Paris Brain Institute / www.dejuansanzlab.org / ERC / FENS-Kavli Scholar / Young Academy of Spain / CNRS
PhD Scientist Engineer
INSERM - Neurocentre Magendie - Bordeaux
Neurosciences Research
Behaviour _ Histology _ Biochemistry
Glia-neuron interactions - Astrocytes, Synapses, Behaviour, & Stress
Principal Investigator, CRCHUM
Associate Professor
Dept. Neuroscience
Université de Montréal
www.murphyroyallab.org
Neurobiology of Stress workshop
www.stress2026.com
phd student in neuroscience
university of bonn
https://henneberger-lab.com
