Richard Unwin

BBC sport website..
1) Test match
2) Will Isak go to Liverpool for £130m
3) ManU (1st game in 2 weeks)
3) Dewsbury-Hall for £28m?
4) Son to LA Galaxy for a record fee
5) Morecambe are gone.

We've got our priorities waaaaaay wrong.

Communities should come before obscene amounts of cash #swfc

Chansiri knows the price of everything but the value of nothing.

He's living in a fantasy land and we're the result of his failure. 😔🦉

I really wish this wasn't true... #swfc

Absolutely. Or better still go to Leicester then at kick off just sit down on the pitch and refuse to move. It's on TV. Would be a real statement. And I reckon fans on both sides would applaud you to the rafters for it. #swfc

Someone's GOT to photoshop Chansiri onto this.... 🤣🤣

🤣🤣🤦‍♂️🤦‍♂️🤦‍♂️

And no obvious way out...

Can the last person out of #swfc please turn out the lights?

Chansiri probably can't even afford the electric bill...

🤦‍♂️😔😔🦉

Complete shambles. Its just...falling apart.

Bannan next? Not a clue why he'd stay, now...

Call for 20 Assistant Professor positions Karolinska Institutet is a world-leading medical university with a long and proud history of ground-breaking research. We are now recruiting outstanding early-career researchers with particularly exce...

Wow

Karolinska Institutet is recruiting 20 outstanding early-career researchers for assistant professor positions

ki.se/en/about-ki/...

Of course. Amstel 'coffee' 🤣🤣

Nice early start at the Test match 😁 #ENGIND

Given the number of leaks, messages and garbage that was floating around a couple of weeks ago - and recent departures - I'd say that no news is bad news... 😬

Well shit.... 🤦‍♂️🤦‍♂️
#swfc

Deborah Prentice stood with Duncan Ivison in front of a background of trees and town-square buildings.

Introducing the UK's first cross-city innovation partnership with @cam.ac.uk.

University collaboration is better than competition to boost innovation.

Professor Deborah Prentice and Professor @duncanivison.bsky.social write @timeshighered.bsky.social.

www.timeshighereducation.com/opinion/univ...

Centre to study how exposome causes chronic inflammatory disease A new Medical Research Council (MRC) centre will investigate how the environment interacts with our immune system to trigger chronic inflammatory diseases.

Super excited to announce that MRC has funded a new Centre of Research Excellence in Exposome Immunology. Working together, Manchester and Oxford are going to tackle a major challenge of our times. For those who wonder what the Exposome is - see yesterday's posts! www.ukri.org/news/centre-...

Come and join us in Manchester... We are looking for candidates interested in vascular health and neurodegeneration. This project is specifically exploring how menopause may increase Alzheimer's risk.
We also have a postdoc position available: www.jobs.manchester.ac.uk/Job/JobDetai...

▶️▶️ To all mass spec enthusiasts: A postdoc position (three years) is available in our international group. Please apply if you are interested in structural MS and in developing novel cross-link ing MS workflows!🧪
Thanks @diegofgar.bsky.social for sharing!
#teammassspec
#AcademicSky
#ChemSky

Nope.

It's definately contaminant driven. If we load a 10th of what we'd normally load it looks fine. If we dilute the sample in the vial and load more volume - up to an equivalent on-column loading of protein in some cases, that also looks fine. 🤦‍♂️

Complement Tx set to initiate clinical trials with novel gene therapy in fighting macular degeneration These are exciting times for biotech business Complement Therapeutics, which stands on the cusp of an important milestone in its area of expertise on both sides of the Atlantic.

Progress... 👍😁

www.businessweekly.co.uk/posts/comple...

Rosamund Clifford from the @rdunwin.bsky.social lab now presents her work on "Measuring the Mouse Complementome" focussing on complement proteins. #BSPR2025

Amen to that! 😂

1000% this...

"Very short gradient single shot experiments seem like an incredibly bad idea to me with my scant 20 years experience in proteomics. I do not understand why smart folks think deep proteome profiling is possible with little separation of very complex peptide digests."

Ah now that we've not tried. Other samples, including pure versions of this peptide, our BSA QC and an old (degraded but workable) sample from this study look OK so I think LC is sound and it's something in the sample(s) but Ive no idea what....

Nope. Same. But that's a great thought!

And the second peak is not the contaminant, which.is what I thought at first - we see this on several (not all) peptides. Light and heavy.

Not that we can see. Middle of gradient. 1st peak stays static w.r.t.intensity despite increased loading, when we load double the second peak appear with similar area (but lower height/wider) and as we increase load only the second new peak gets bigger. Thinking contaminant in sample but it's... odd

Yup. If we run heavy only on same method it looks perfect. Guess is something in the sample (looks fine with a low load but gets worse as we load more fits with that too). But give no idea what. I've run a LOT of wierd clinical samples - not as wierd as some of yours! - but never seen this...

Agilent 1200. 100ul/min flow.

Everything looks great if you run heaviest only. It's gotta be something in the sample. Not a clue what though...