- We performed the first detailed analysis of semi-tryptic peptides and identified organ-specific cleavage motifs.
- Our findings stress the importance of considering post-mortem effects in proteomics studies to avoid bias and incorrect conclusions.
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- Post-mortem protein changes are organ-specific, with significant differences in the number of differentially abundant proteins.
- While overall changes in the heart are minimal, subcellular compartmentalization is disrupted within just 2 hours post-mortem.
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The official channel for the British Society for Proteome Research
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Kvalitet, kunskap och kreativitet. Sedan 1477.
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