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@blastomyces.bsky.social

Adult Infectious Diseases

489 Followers  |  1,902 Following  |  6 Posts  |  Joined: 19.11.2024  |  1.8455

Latest posts by blastomyces.bsky.social on Bluesky

Clinical Outcomes and Perspectives of People With HIV-1 12 Months After Initiation of Long-acting Cabotegravir and Rilpivirine in an Observational Real-World US Study (BEYOND) Long-acting c abotegravir + rilpivirine (CAB+RPV LA) administered monthly or every 2 months is recommended by treatment guidelines for maintenance of virologic suppression in people with HIV-1. In clinical trials, CAB+RPV LA demonstrated non-inferiority versus FDA-approved daily oral therapy, and outcomes in real-world settings can supplement these results. We present Month 12 results of BEYOND.MethodsBEYOND is an ongoing, 2-year, multicenter, prospective, observational real-world study of adults initiating CAB+RPV LA in the United States. Key outcomes included reasons for initiating, virologic outcomes, adherence, and patient-reported outcomes related to treatment satisfaction and treatment challenges at baseline and Month 12.ResultsIn total, 308 participants (median age, 45 years; 83% identified as male; 39% identified as Black) initiated CAB+RPV LA most commonly because of treatment fatigue, adherence anxiety with daily oral therapy, and/or convenience. Of participants with baseline viral load data, 97% (194/200) had a viral load <50 copies/mL for their most recent test reported at Month 12. Mean treatment satisfaction scores increased significantly from baseline to Month 12 and 97% (223/229) of participants preferred LA versus oral treatment at Month 12. Proportions of participants reporting β€œalways” or β€œoften” experiencing challenges related to HIV-1 treatment (fear of disclosure, adherence anxiety, reminder of HIV-1 status, and feeling stigmatized) decreased from baseline to Month 12.ConclusionsMonth 12 results from the real-world BEYOND study support the effectiveness of CAB+RPV LA for maintenance of virologic suppression and as a preferred treatment option for people with HIV-1.

In the BEYOND study (308 participants, median age 45), 97% had viral load <50 copies/mL at 12 months. 97% preferred CAB+RPV LA over oral therapy. Treatment challenges decreased significantly. πŸ“‰πŸ’Š

#idsky

20.04.2025 01:00 β€” πŸ‘ 2    πŸ” 1    πŸ’¬ 0    πŸ“Œ 1
The latest deeply confusing post by Trump in the ongoing circle jerk of mixed messages over tariffs. The post says.

NOBODY is getting "off the hook" for the unfair Trade Balances, and Non Monetary Tariff Barriers, that other Countries have used against us, especially not China which, by far, treats us the worst!
There was no Tariff "exception" announced on Friday. These products are subject to the existing 20% Fentanyl Tariffs, and they are just moving to a different Tariff "bucket." The Fake News knows this, but refuses to report it. We are taking a look at Semiconductors and the WHOLE ELECTRONICS SUPPLY CHAIN in the upcoming National Security Tariff Investigations. What has been exposed is that we need to make products in the United States, and that we will not be held hostage by other Countries, especially hostile trading Nations like China, which will do everything within its power to disrespect the American People. We also cannot let them continue to abuse us on Trade, like they have for decades, THOSE DAYS ARE OVER! The Golden Age of America, which includes the upcoming Tax and Regulation Cuts, a substantial amount of which was just approved by the House and Senate, will mean more and better paying Jobs, making products in our Nation, and treating other Countries, in particular China, the same way they have treated us. The bottom line is that our Country will be bigger, better, and stronger than ever before. We will, MAKE AMERICA GREAT AGAIN!

The latest deeply confusing post by Trump in the ongoing circle jerk of mixed messages over tariffs. The post says. NOBODY is getting "off the hook" for the unfair Trade Balances, and Non Monetary Tariff Barriers, that other Countries have used against us, especially not China which, by far, treats us the worst! There was no Tariff "exception" announced on Friday. These products are subject to the existing 20% Fentanyl Tariffs, and they are just moving to a different Tariff "bucket." The Fake News knows this, but refuses to report it. We are taking a look at Semiconductors and the WHOLE ELECTRONICS SUPPLY CHAIN in the upcoming National Security Tariff Investigations. What has been exposed is that we need to make products in the United States, and that we will not be held hostage by other Countries, especially hostile trading Nations like China, which will do everything within its power to disrespect the American People. We also cannot let them continue to abuse us on Trade, like they have for decades, THOSE DAYS ARE OVER! The Golden Age of America, which includes the upcoming Tax and Regulation Cuts, a substantial amount of which was just approved by the House and Senate, will mean more and better paying Jobs, making products in our Nation, and treating other Countries, in particular China, the same way they have treated us. The bottom line is that our Country will be bigger, better, and stronger than ever before. We will, MAKE AMERICA GREAT AGAIN!

🚨TARIFF UPDATE:

Tariffs are non-negotiable, negotiable, but not a negotiating tactic. They are permanent until they are paused but they will never be paused, until they are paused which means they increase. Permanent exemptions already announced are temporary, but nothing has been announced.
🀑πŸŽͺ

13.04.2025 20:23 β€” πŸ‘ 1651    πŸ” 493    πŸ’¬ 123    πŸ“Œ 90
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Vancomycin Taper trial presented by @dremilymcd.bsky.social #ESCMID2025. In people who get better by day 10 should we stop or give taper? Reduced recurrences by primary outcome timepoint but the KM suggests it may be just delaying rather than truly preventing recurrence? #IDSky

13.04.2025 15:38 β€” πŸ‘ 26    πŸ” 12    πŸ’¬ 0    πŸ“Œ 0
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The Trump Administration Accidentally Texted Me Its War Plans U.S. national-security leaders included me in a group chat about upcoming military strikes in Yemen. I didn’t think it could be real. Then the bombs started falling.

In 25 years of covering national security, I’ve never seen a story like this: Senior Trump officials discussed planning for the U.S. attack on Yemen in a Signal group--and inadvertently added the editor-in-chief of The Atlantic. www.theatlantic.com/politics/arc...

24.03.2025 16:11 β€” πŸ‘ 16636    πŸ” 6502    πŸ’¬ 787    πŸ“Œ 2591
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10 FAQs on MMR and Measles Protection Boosters, waning immunity, checking titers, infection induced immunity, and more

@kkjetelina.bsky.social
Your measles FAQ is very useful and timely, thank you!

I've been searching PubMed, etc. looking for clear recommendations, guidelines, data for measles boosters by year vaccinated like you show in your table in the FAQ. Where did you find that data?

#primarycare #IDsky

14.03.2025 22:56 β€” πŸ‘ 33    πŸ” 11    πŸ’¬ 3    πŸ“Œ 0
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MAGA influencers are out in full force tonight, making up things that were not in this resolution.

Congrats on getting your $4.5 trillion in tax cuts for the wealthy, $19 trillion in added deficit spending, and $880 billion in Medicaid cuts through this initial step, though.

26.02.2025 06:09 β€” πŸ‘ 8013    πŸ” 2266    πŸ’¬ 433    πŸ“Œ 116

We are absolutely not prepared for emerging threatsβ€”just look at the Texas measles outbreak.

Over 120 cases, spread to another state, and yet silence from the CDC, HHS Secretary, and other government agencies while dismantling ACIP and public health in this country.

26.02.2025 13:41 β€” πŸ‘ 38    πŸ” 14    πŸ’¬ 3    πŸ“Œ 0

Enjoy the listeria coming our way, and remember to thank this guy

25.02.2025 02:58 β€” πŸ‘ 23    πŸ” 12    πŸ’¬ 1    πŸ“Œ 0

Russia invaded the sovereign nation of Ukraine. Vladimir Putin is the aggressor. I’m not going to let Trump rewrite history.

25.02.2025 13:45 β€” πŸ‘ 837    πŸ” 193    πŸ’¬ 45    πŸ“Œ 12

This is an extremely interesting analysis.

20.02.2025 13:34 β€” πŸ‘ 12    πŸ” 8    πŸ’¬ 0    πŸ“Œ 0
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Texas Banned Abortion. Then Sepsis Rates Soared. ProPublica’s first-of-its-kind analysis is the most detailed look yet into a rise in life-threatening complications for women experiencing pregnancy loss under Texas’ abortion ban.

NEW: Pregnancy became far more dangerous in Texas after the state banned abortion, according to ProPublica’s first-of-its-kind analysis, which found the sepsis rate for women hospitalized as they miscarried in the 2nd trimester shot up by more than 50%.

https://propub.li/43487Tj

20.02.2025 12:00 β€” πŸ‘ 13180    πŸ” 7039    πŸ’¬ 530    πŸ“Œ 726

"Law and order" in the Trump era: if you bow down to the head of the U.S. government, he may help you - whether you're awaiting trial for sex crimes in Europe or doing time in the USA for physically assaulting police.

18.02.2025 02:45 β€” πŸ‘ 21557    πŸ” 3977    πŸ’¬ 482    πŸ“Œ 138
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JUST IN: Another medical horror story in an affidavit from a USAID employee stationed overseas. Says his pregnant wife was not medevac-ed for emergency health care because of directives from DC. Took intervention of a U.S. senator to reverse β€” but was too late. s3.documentcloud.org/documents/25...

18.02.2025 01:40 β€” πŸ‘ 20282    πŸ” 9025    πŸ’¬ 823    πŸ“Œ 934

This is why you fight these cowards.

The moment you stand up to them, they crumble.

Homan has nothing. The Fourth Amendment is clear and I am well within my duties to educate people of their rights.

He can threaten me with jail and call names all he wants. He’s got nothing else.

18.02.2025 03:17 β€” πŸ‘ 150300    πŸ” 26697    πŸ’¬ 7824    πŸ“Œ 1685
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1/29: First plane crash in 16 years in DC
1/31: Crash in Philly
2/5: Delta flight struck in Seattle
2/6: Flight wrecks in Alaska
2/10: Crash in Scottsdale
2/12: Military jet crashes in San Diego
2/16: Crash in Covington, GA

7 crashes since the WH congratulated itself for β€œrestoring aviation safety”

16.02.2025 15:01 β€” πŸ‘ 60016    πŸ” 23428    πŸ’¬ 2163    πŸ“Œ 1578

If you wanted to cut waste, fraud, and abuse, you would empower the inspectors general.

If you wanted more waste, fraud, and abuse, you would fire them.

17.02.2025 14:17 β€” πŸ‘ 125068    πŸ” 31457    πŸ’¬ 2159    πŸ“Œ 1264
Post image 15.02.2025 00:55 β€” πŸ‘ 12340    πŸ” 2418    πŸ’¬ 191    πŸ“Œ 84
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I fear they’re coming for ALL school vaccine mandates next. Including measles, mumps and rubella.

15.02.2025 15:32 β€” πŸ‘ 21071    πŸ” 6225    πŸ’¬ 2275    πŸ“Œ 807
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the single most un-american and anti-constitutional statement ever uttered by an american president

15.02.2025 18:39 β€” πŸ‘ 97914    πŸ” 21338    πŸ’¬ 5366    πŸ“Œ 2364
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ACT UP’s Radical Activism Saved Lives During the AIDS Epidemic The movement stood up to the president, pharmaceutical companies, and the CDC.

This is a very heavy day for us.

To those who lost their jobs, we are with you and will work with you again.

To those struggling to see a future for our work, do not give up.

Real change in public health has always been a battle. Now it’s a war.

We will win it.

This is our country. #RISEUP

14.02.2025 21:57 β€” πŸ‘ 5160    πŸ” 1217    πŸ’¬ 85    πŸ“Œ 45

This is so smart. @petebuttigieg.bsky.social , thoughts ?

And if you see this. A reminder. This is not Twitter. You can engage here and have thoughtful discussions !

We all look forward to reading your thoughts

14.02.2025 18:15 β€” πŸ‘ 82681    πŸ” 13934    πŸ’¬ 5853    πŸ“Œ 1067
KNOW YOUR
RIGHTS
IN CASE OF ICE:
CONOCE TUS DERECHOS
EN CASO DE ENCUENTRO CON ICE:

KNOW YOUR RIGHTS IN CASE OF ICE: CONOCE TUS DERECHOS EN CASO DE ENCUENTRO CON ICE:

DO NOT OPEN YOUR DOOR.
ICE cannot enter your home without a warrant signed by a judge.
Tell the agents to show you the warrant by sliding it under the door.
NO ABRAS TU PUERTA.
ICE no puede entrar a tu casa sin una orden firmada por un juez. Diles a los agentes que te muestren la orden deslizΓ‘ndola debajo de la puerta.

DO NOT OPEN YOUR DOOR. ICE cannot enter your home without a warrant signed by a judge. Tell the agents to show you the warrant by sliding it under the door. NO ABRAS TU PUERTA. ICE no puede entrar a tu casa sin una orden firmada por un juez. Diles a los agentes que te muestren la orden deslizΓ‘ndola debajo de la puerta.

ASK THEM
TO LEAVE.
If ICE doesn't have a warrant, tell them you do not consent for them to enter your home and ask them to leave. At work, ICE cannot enter employee-only areas without permission.
2
PÍDALES QUE SE VAYAN.
Si ICE no tiene una orden judicial, diles que no das tu consentimiento para que entren a tu casa y pΓ­deles que se vayan. En el trabajo, ICE no puede ingresar a Γ‘reas exclusivas para empleados sin permiso.

ASK THEM TO LEAVE. If ICE doesn't have a warrant, tell them you do not consent for them to enter your home and ask them to leave. At work, ICE cannot enter employee-only areas without permission. 2 PÍDALES QUE SE VAYAN. Si ICE no tiene una orden judicial, diles que no das tu consentimiento para que entren a tu casa y pídeles que se vayan. En el trabajo, ICE no puede ingresar a Ñreas exclusivas para empleados sin permiso.

REMAIN SILENT.
You have the right to remain silent.
If the agents ask you questions, tell them,
"I wish to remain silent."
PERMANECE EN SILENCIO.
Tienes derecho a permanecer en silencio.
Si los agentes te hacen preguntas, diles:
"Deseo permanecer en silencio".

REMAIN SILENT. You have the right to remain silent. If the agents ask you questions, tell them, "I wish to remain silent." PERMANECE EN SILENCIO. Tienes derecho a permanecer en silencio. Si los agentes te hacen preguntas, diles: "Deseo permanecer en silencio".

It is perfectly legal to know your rights and to educate others about them, too.

EVERYONE in the United States, citizen or not, has rights. I will not allow this administration to intimidate us from helping you know about them.

Here’s our shareable guide ⬇️: (pt. 1/2)

14.02.2025 23:47 β€” πŸ‘ 115303    πŸ” 34116    πŸ’¬ 1821    πŸ“Œ 983

DISEASES ERADICATED OR DECIMATED BY SCIENCE:
1. Chickenpox
2. Diphtheria
3. Measles
4. Pertussis
5. Pneumococcal Infection
6. Polio
7. Tetanus
8. Typhoid
9. Yellow Fever
10. Smallpox

DISEASES ERADICATED OR DECIMATED BY RFK JR. OR PRAYER:
1.
2.
3.
4.
5.
6.
7.
8.
9.
10.

13.02.2025 17:05 β€” πŸ‘ 49606    πŸ” 16828    πŸ’¬ 1183    πŸ“Œ 662
Black and white photo of Aimee Wilcox and Dr Seward Miller at a microscope in one of CDC's first labs.

Black and white photo of Aimee Wilcox and Dr Seward Miller at a microscope in one of CDC's first labs.

July 1, 1946 CDC was created, in the heart of the south, to combat malaria in the US. That year there were ~48,610 US malaria cases. With the help of WHO and others, CDC established case reporting, investigation, and preventative measures. By 1957, endemic malaria had been eradicated in the US.

13.02.2025 03:18 β€” πŸ‘ 785    πŸ” 167    πŸ’¬ 9    πŸ“Œ 5
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BREAKING: NIH admits funding freeze is illegal, will resume issuing grants An internal memo issued February 12 was obtained by Popular Information.

BREAKING

On Monday, Popular Information broke the news that the NIH had frozen virtually all grant funding in violation of 2 federal court orders

On Wednesday, NIH leadership distributed a memo, acknowledging that its funding freeze was illegal and directing staff to resume issuing grants.

12.02.2025 19:36 β€” πŸ‘ 26271    πŸ” 7780    πŸ’¬ 361    πŸ“Œ 402
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'Reboot' Revealed: Elon Musk's CEO-Dictator Playbook In 2022, one of Peter Thiel's favorite thinkers envisioned a second Trump Administration in which the federal government would be run by a β€œCEO”

www.thenerdreich.com/reboot-elon-...

12.02.2025 14:49 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

🧡 If you’re applauding the abolishment of the Department of Education, you need to do a little research. You have ZERO clue what the DOE actually does.

Here’s a reality check on what the Department of Education actually does:
(1/14)

09.02.2025 18:29 β€” πŸ‘ 6349    πŸ” 2377    πŸ’¬ 208    πŸ“Œ 180
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NIH plans to slash support for indirect research costs, sending shockwaves through science The NIH said Friday night that it would slash support for indirect costs on all existing and future grants to 15%

This change will accomplish one thing - kill medical research in US academic institutions.
That's not hyperbole and the best way I can explain this to the lay public.
Slashing indirect costs to 15% is a move to destroy the academic enterprise.
Pass it on.
www.statnews.com/2025/02/07/n...

08.02.2025 02:26 β€” πŸ‘ 328    πŸ” 130    πŸ’¬ 9    πŸ“Œ 9
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Of course it’s a coup Miss the obvious, lose your republic

open.substack.com/pub/snyder/p...

08.02.2025 18:44 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Under fascism, no one is safe.

Universities stayed quiet as the admin targeted DEI & foreign aid, censored research, etc.

Now, they face devastating cuts to indirect cost rates, threatening research & operations.

Silence won’t protect institutions. It won’t protect people; it never does.

08.02.2025 13:28 β€” πŸ‘ 23162    πŸ” 6297    πŸ’¬ 339    πŸ“Œ 241

@blastomyces is following 20 prominent accounts