Tim

If you're at #cellbio2025, @atmolines.bsky.social Hernan Garcia and I invite you to attend our Minisymposium “Physical Cell Biology from Molecules to Organisms” for incredible talks on epigenetic mechanical memory, viscoelasticity, cortical flows, morphogenesis, tissue wetting, size scaling, et al!

Promotional flyer for openRxiv at Cell Bio 2025, December 6-10 in Philadelphia, PA, booth #1134, with a background of illustrated cells.

openRxiv is heading to Cell Bio 2025 in Philadelphia 🔬
See us at Booth 1134 with Cold Spring Harbor Laboratory Press from December 6-10. We’re excited to meet the community, share what we’re building, and talk about the future of open science. We hope to see you there.

📣 Help choose @jcb.org's cover of the year! Explore 12 breathtaking images submitted by our talented authors and vote for your favorite. Voting closes on Wednesday, December 31 👉 www.surveymonkey.com/r/JCB2025Cov...

#CellBio2025 #ScienceArt

I recall the first time you did this!! A fabulous demonstration of biology’s beauty.

The more salient issue is the overall credulity of the models, as you note, and with which I completely agree. This is a major weakness when evaluating research papers, maybe a different story with grant applications?

Yes! qed and other models have never, in my experience, offered an alternative explanation/model for the observations made in a paper. Would be a big advance if they did that.

I would just note that in my experience reading 1000s of reviewer comments this is very rare with human reviewers also!

Although the original thread from @andrea-musacchio.bsky.social was deleted, he was correct to bring his concerns to editors who are key players in how/where/when controversial papers are published.

Appreciate Richard's points on the larger issue (not, as he notes, the specifics of LLPS).

Hm I’ve seen examples where AI models very effectively challenge unsupported assertions in research manuscripts. Might be possible here?

Also the pilot as described will train their LLM for predictive power, not quite the same as producing the “average output”

I imagine a triage mechanism that accelerates decisions on obviously low quality applications. More involvement than that seems dicey.

Interested to learn the outcome of this testing either way though.

Genesis Mission A National Initiative to Accelerate Science Through AI. Genesis Mission is a national initiative to build the world's most powerful scientific platform to accelerate discovery science, strengthen nati...

Here's the website for the initiative which includes a long list of partners, naming all the big tech players.
genesis.energy.gov

Has anyone seen this executive order establishing "Genesis Mission" at the DOE?

In particular the provision that this initiative will be provided with "scientific datasets" and "experimental and production tools" to further its mission.

www.whitehouse.gov/presidential...

kill meeeeee

Read our top papers in cell bio from the past year, then come find me at #CellBio2025 and tell me what you thought!

Beautiful!

Get pumped!! My first CellBio as executive editor at LSA!
💪💪💪🥳🥳🥳

Why start with “uh-oh” instead of “at last”? This debate is real and will certainly play out in many venues. I’m hoping bluesky is among them!

The assumed link between conceptual advance and journal impact factor is alive and well 😔

The latest AI slop published by @springernature.com (great work!) has me wondering if, unlike the rat testicle one, this could be explained by English illiteracy? The graphics are not obviously wrong. Does anyone know?

spicy!

genesdev.cshlp.org/content/33/2...

Today!! Freshly jetlagged from #sfn25 in San Diego, I will discuss publishing negative data at the fantastic R^3 series (Scientific Rigor, Reproducibility, and Reporting) @rockefeller.edu

Check out their website for other topics they cover: www.rockefeller.edu/research/r3/

SAVE THE DATE! Stoked to organize the 2026 Santa Cruz Developmental Biology Meeting with @rashmi-priya.bsky.social, @lowelab.bsky.social, and Shelbi Russell. Come learn about Biomedicine, Biomechanics, and the Biosphere, August 24-28, 2026. Registration dates, etc., coming soon! Please RT

Currently sitting in by far the best session at #sfn25 [room is a comfortable temperature]

Obsessed w this work we just published @lsajournal.org :

This acetyltransferase mediates metabolic adaptation to starvation… but can be replaced by a 2 degree temperature shift!!

This is why fruit flies you guys!

Attending #SfN25 in San Diego? Stop by @rupress.org booth #3719 to discuss your research and our journal! Don't forget to pick up our #Neuroscience Collection magazine 📚 We look forward to meeting you! 💬 💡

Two days left here at #sfn2025!

If you’re casting about for a place to send your cool neuroscience paper, check out what we publish at LSA 👇

👌

Weather update here in San Diego 🥰

See a sampling of our neuro papers here: www.life-science-alliance.org/content/neur...

Today at #sfn2025 I’ll be at @rupress.org booth 3719! Come say hi and chat about the many routes to publishing your neuroscience work!

Won’t be enjoying my nice patio much during a soggy few days in San Diego. But still excited for dry/indoor science here at #sfn2025