Páll Melsted's Avatar

Páll Melsted

@pmelsted.bsky.social

Professor @hi.is in CS, head of rna seq data analysis at decode genetics (views are mine). Bioinformatician, epistemic trespasser, &c. ps. I hate GTF files

1,499 Followers  |  91 Following  |  34 Posts  |  Joined: 29.09.2023  |  1.926

Latest posts by pmelsted.bsky.social on Bluesky

Today I found out that the Pacbio tools for working with barcodes and adapters in Kinnex are called lima and skera. To whomever came up with that joke, I salute you, you’ve reached 50% of the audience

31.10.2025 14:06 — 👍 0    🔁 0    💬 0    📌 0

Retracting a paper is going to hurt

21.10.2025 20:01 — 👍 2    🔁 0    💬 0    📌 0

All right, I posed this question to my PhD student this morning and he looked at me funny and asked if it was a trick question

What is the running time of this code

a, b = 0, 1
for _ in range(2, n+1):
a, b = b, a + b
return b

07.10.2025 22:12 — 👍 1    🔁 0    💬 0    📌 0

Happy Q4 for those who celebrate

01.10.2025 20:31 — 👍 1    🔁 0    💬 0    📌 0

Today I fixed a humming converter and an intercom receiver set from the 70’s. I’m surprised at how good ChatGPT is at diagnosing problems and coming up with fixes for hardware that is older than me. Since I didn’t have to replace the units I can justify the cost and environmental impact of AI

27.09.2025 23:28 — 👍 3    🔁 0    💬 0    📌 0

The Genome Informatics conference (@ Cold Spring Harbor Lab, Nov 5 - 8) abstract deadline is **today**. We welcome your submissions! Topics include:
- PanGenomes
- Genome Assembly & Seq. Algos.
- Algorithmic Evo. Bio
- Single Cell & Spatial Omics
- Microbial Genomics
- AI/ML & Integrative Omics
🙏🙏🙏

22.08.2025 15:00 — 👍 11    🔁 6    💬 0    📌 0
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a group of men in suits are dancing around a coffin . ALT: a group of men in suits are dancing around a coffin .
15.08.2025 05:14 — 👍 2    🔁 0    💬 0    📌 0
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Perfect marketing doesn’t exi…

05.07.2025 11:22 — 👍 0    🔁 0    💬 0    📌 0

Glengarry Glen Ross

05.07.2025 10:41 — 👍 1    🔁 0    💬 0    📌 0
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It is by the juice of coffee that thoughts acquire speed …

27.06.2025 12:39 — 👍 1    🔁 0    💬 0    📌 0
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Postdoctoral Researcher in Computational Genetics The research group of Oliver Stegle looks for a postdoctoral researcher to join a collaborative project with GSK with the goal to apply computational methods to investigate the effects of rare variant...

Job alert: Join us for a postdoc in AI in genetics at @EMBL Heidelberg! Great collaboration with @Adrian Cortes @GSK, aiming to develop new tools to elucidate genetic effects using population-scale cohorts and single-cell readouts. Please share!

embl.wd103.myworkdayjobs.com/de-DE/EMBL/d...

26.06.2025 10:00 — 👍 14    🔁 17    💬 0    📌 2

I misread that as “message” which would have been more impressive 🚩

24.06.2025 12:57 — 👍 1    🔁 0    💬 0    📌 0
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Epistemic failure of epistemic failure Earlier this year I came across this interesting post by mathematician Daniel Litt, where he pondered how many intrinsically true results in mathematics have been published with erroneous proofs: D…

liorpachter.wordpress.com/2025/06/03/e...

03.06.2025 20:30 — 👍 17    🔁 3    💬 0    📌 0

I have an opportunity to hire a staff scientist for my lab. Looking for someone with outstanding skillset in ML/statistics, genomics applications; interest in mentoring, strong publication record, PD experience required.

Email CV to me+cc my assistant (see 'contact' on my website). Ad to follow.

01.06.2025 15:33 — 👍 83    🔁 108    💬 3    📌 3

I had Ágætis byrjun on repeat for a long time. Just happened upon this on Spotify the other day and I’d forgotten how good it was

20.05.2025 19:30 — 👍 2    🔁 0    💬 0    📌 0
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In Iceland spring is not something you define as season based on weather but more from the arrival of migratory birds

09.05.2025 09:01 — 👍 3    🔁 0    💬 0    📌 0

For me it’s kind of in the same category as woodworking videos that create beautiful custom tables from slabs of oak. Looks great and maybe someday I can use this.

05.05.2025 12:25 — 👍 1    🔁 0    💬 1    📌 0
TikTok - Make Your Day

vm.tiktok.com/ZNd6ebsjN/

I actually learned something new here

05.05.2025 09:41 — 👍 2    🔁 0    💬 1    📌 0
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My favorite brainrot is an account on TikTok that solves complicated integrals on a blackboard with colored chalk.

05.05.2025 09:39 — 👍 4    🔁 0    💬 1    📌 0

When you refresh to see new posts you lose where you were. This is the only thing I miss about twitter

02.05.2025 20:21 — 👍 1    🔁 0    💬 0    📌 0
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There is something refreshingly honest about moving the goalpost this blatantly. Adjusting for multiple testing? Not in my house ☝️

30.04.2025 22:20 — 👍 3    🔁 1    💬 0    📌 0
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Join our lab to study transcriptional regulation in mouse germ cells and embryonic stem cells at @haskoliislands.bsky.social in beautiful Reykjavík!
Apply here: tinyurl.com/34y6jcrd
#epigenetics #TranscriptionFactors #transcriptomics #stemCells #pluripotency

22.04.2025 17:24 — 👍 18    🔁 14    💬 0    📌 1
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Hold my mead. 1200 from Iceland

handrit.is/manuscript/v...

07.04.2025 17:49 — 👍 5    🔁 1    💬 0    📌 0

Today I gave a lecture in a brand new lecture hall where the projector was acting weird. Turned out that the control panel showed green for when the projector was off, you had to press the button wait 10 seconds and then it turned red.

I think this should be a case study in UI design

04.03.2025 21:10 — 👍 5    🔁 1    💬 0    📌 0
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Periodic cooking of eggs - Communications Engineering Emilia Di Lorenzo and colleagues propose an approach to address the energy transport problem of cooking the albumen and yolk of a boiled egg at their optimal temperatures without separation. By altern...

I might need to replicate this paper www.nature.com/articles/s44...

07.02.2025 13:20 — 👍 2    🔁 0    💬 0    📌 0

Somehow I would be more confident that the Tesla could drive autonomously if the auto mode on the windshield wipers worked.

23.01.2025 21:52 — 👍 0    🔁 0    💬 0    📌 0
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Ironically this is the best content on that other place

13.01.2025 14:19 — 👍 2    🔁 0    💬 0    📌 0
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a man in a suit and tie is holding a bucket of popcorn with the words here for it all below him ALT: a man in a suit and tie is holding a bucket of popcorn with the words here for it all below him
06.01.2025 22:30 — 👍 1    🔁 0    💬 0    📌 0
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Beautiful polar stratospheric clouds today

05.01.2025 17:25 — 👍 2    🔁 0    💬 0    📌 0

Acceptable substitutes are The Hours, The Four Seasons, and Succession (season 2).

05.12.2024 01:41 — 👍 1    🔁 0    💬 0    📌 0

@pmelsted is following 20 prominent accounts