Aztreonam, broad spectrum…cough…really…awkward silence…

“Bold”, other adjectives are available…miss you both! Currently walking Abel Tasman Track.

NEW EPISODE!

This week Callum takes the boldest step yet in improving the podcast: getting rid of Jame!

Join Callum & Alyssa this week as they Migrate the Marvellous Mountains of Minutiae on Moulds, (di)Morphs, Many yeasts and Mycology in general!

#IDsky

podcasts.apple.com/gb/podcast/i...

Antibiotic duration for common bacterial infections—a systematic review AbstractBackground. Reducing antibiotic duration is a key stewardship intervention to mitigate antimicrobial resistance (AMR). We examined current evidence

How long should bacterial infections be treated with antibiotics?
Review summarizing key RCTs & international consensus for a holistic guide to antibiotic durations, highlighting important caveats: more evidence needed for severe infections & in LMICs
doi.org/10.1093/jaca...
#JACAMRNews

BSAC supports calls for UK Government to strengthen action on antimicrobial resistance - The British Society for Antimicrobial Chemotherapy

As drug-resistant infections continue to rise, BSAC is urging the government to invest in the infection workforce by prioritising education and improved diagnostics - key interventions that can reduce the overuse and misuse of antimicrobials, the primary drivers of #AMR. bsac.org.uk/bsac-support...

This study audited the prescribing of antibiotics, using patient medical charts at a tertiary-level public hospital, in preparation for the implementation of an #AntimicrobialStewardship programme:
https://doi.org/10.1093/jacamr/dlae219
#JACAMRNews #IDSky

Reflecting on Fleming’s caveat: the impact of stakeholder decision-making on antimicrobial resistance evolution Antimicrobial resistance poses one of the greatest and most imminent threats to global health, environment and food security, for which an urgent response is mandated. Evolutionary approaches to tackl...

A new article exploring important historical case studies that shaped the development, use and long-term efficacy of β-lactam #antibiotics. www.microbiologyresearch.org/content/jour...

Impact of educational intervention on knowledge of antimicrobial resistance and antibiotic use patterns among healthcare students: a pre- and post-intervention study - BMC Medical Education Background Antimicrobial resistance (AMR) is a growing global health threat, partly driven by inappropriate antibiotic use. Healthcare students, as future practitioners, must have a good understanding...

Investing in #AMR education today shapes responsible prescribing tomorrow... but more targeted efforts are needed to tackle 'persistent misconceptions.' bmcmededuc.biomedcentral.com/articles/10....

ICYMI: this adapted UK AWaRe list reached through consensus will support national #AntimicrobialStewardship and usage targets of the UK 2024–29 NAP
https://doi.org/10.1093/jacamr/dlae218
@dianeashiru.bsky.social @raseaton66.bsky.social @aliciad3.medsky.social
#JACAMRNews

IV to oral antibiotic switch in patients with uncomplicated E. faecalis BSI showed shorter length of hospital stay and no significant increase in the risk of treatment failure—this could be a promising strategy for selected patients:
https://doi.org/10.1093/jacamr/dlaf004
#JACAMRNews

The @biainfection.bsky.social LearnInfection platform is free to trainee members and is a brilliant resource for studying for the FRCPath Pt1/CICE exam.

If you’re an early years trainee yet to sit this exam, give it a go!

Screenshot of IDSA cUTI guideline open for public comment

Draft of IDSA cUTI guideline showing steps to follow for selection of therapy

Figure 2 flowchart showing stepwise assessment of IV to PO switch and duration of therapy

Figure showing old vs new definition of uUTI, cUTi, and acute pyelonephritis

‼️The @idsainfo.bsky.social cUTI guideline 📄 draft is now available for public comment🗣️! This version has been reviewed by 15+ orgs & revised according to extensive feedback provided to us. www.idsociety.org/practice-gui...

UTIsky IDsky Medsky PharmSky

Year In Review: Top Infectious Diseases Articles From 2024 In this article a selection of notable peer-reviewed publications from 2024 are provided. Article Selection by: Bassam Ghanem, Pharm.D., MS, BCPS Article Construction by: Timothy P. Gauthier, Pharm.D....

🔥🔥 NEW 🔥🔥
Year In Review: Top Infectious Diseases Articles From 2024
Our new post, a great collaboration with my friend
🌟 @idstewardship.bsky.social
1️⃣6️⃣⚡️🆔 RCTs
7️⃣Syst Reviews/Meta
3️⃣🌏Guidelines ✨️Wiki_Guidelines
#idsky #EMIMCC #medsky #utisky
EnJoy
Share plz!
www.idstewardship.com/year-review-...

Source control Source control Source control Source control Source control Source control Source control Source control Source control Source control Source control Source control Source control Source control Source control Source control Source control Source control
Source control Source control

207996 - Healthcare Science Manager Infection Sciences :Royal Infirmary of Edinburgh

Come join our Infection Service in NHS Lothian as a Healthcare Science Manager! 🔬🧫

apply.jobs.scot.nhs.uk/Job/JobDetai...

An image shamelessly plugging the ID:IOTS podcast having had 250k downloads

250k downloads?

100 episodes?

Podcast going for >3yrs 6months 3 weeks?

Putting up with Callum’s crap for the same amount of time?

Collabs with @febrilepodcast.bsky.social, @letstalkmicro.bsky.social, MicrobeMail & @sidpharm.bsky.social #breakpoints?

COMPLETED IT MATE

#idsky #humblebrag

In a retrospective cohort of asymptomatic patients with urinalysis performed within a preoperative screening protocol, the presence of pyuria increased the odds of antibiotic prescribing 4-fold 😱
Utter madness! #IDsky

Antibiotic Overprescription for “Urinary Tract Infections” Is Associated With Poor Diagnostic Stewardship and Low Adherence to Guidelines Purpose While urinary tract infections (UTIs) are thought to be common among women, as many as 65% of UTI diagnoses may be inaccurate. To identify strategies to improve antibiotic stewardship, we so...

UTI vs "UTI" ⁉️
In this cohort of patients diagnosed with "UTI" only about 30% had symptoms consistent with infection. ED setting and patients with mental status changes are key opportunities for antibiotic stewardship.
onlinelibrary.wiley.com/doi/10.1002/...

Rethinking the “Pan-Culture”: Clinical Impact of Respiratory Culturing in Patients With Low Pretest Probability of Ventilator-Associated Pneumonia AbstractBackground. Respiratory cultures are often obtained as part of a “pan-culture” in mechanically ventilated patients in response to new fevers or leu

Rethinking the “Pan-Culture”:
Respiratory cultures are often obtained as part of a “pan-culture” in mechanically ventilated patients in response to new fevers or leukocytosis, despite an absence of clinical or radiographic evidence suggestive of pneumonia #idsky
academic.oup.com/ofid/article...

In urinary tract infection, antimicrobial therapy matching with in vitro susceptibility predicts a clinical cure better than mismatching predicts a failure
https://doi.org/10.1093/jacamr/dlae188
#JACAMRNews

Oral Versus Intravenous Antibiotic Therapy for Staphylococcus aureus Bacteremia or Endocarditis: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials We conducted a systematic review of randomized, controlled trials (RCTs) to generate more precise estimates of the efficacy and safety of oral versus intravenous antibiotic therapy for Staphylococcus aureus bacteremia or endocarditis.

Oral Versus Intravenous Antibiotic Therapy for Staphylococcus aureus Bacteremia or Endocarditis: A Systematic Review and Meta-Analysis of Randomized, Controlled Trials

#IDSky

This article addresses the issue of #AntimicrobialResistance in Enterobacterales in the East of England, providing data to guide the empirical treatment of UTIs:
https://doi.org/10.1093/jacamr/dlaf003
#JACAMRNews

Al Mohajer et al. found that medical school ranking did not impact the rate of antibiotic days supplied per 100 beneficiaries
Students and providers with over 20 years of experience had the highest days supplied rate:
https://doi.org/10.1093/jacamr/dlae191
#JACAMRNews

Early oral stepdown therapy for infective endocarditis: an international cross-sectional survey on current use in clinical practice There is now strong evidence supporting early oral switch (EOS) from intravenous antibiotics in the treatment of infective endocarditis (IE). Our obje…

🆕💫 Early oral stepdown therapy for infective endocarditis: an international cross-sectional survey on current use in clinical practice ESCMID Study Group for Bloodstream Infections, Endocarditis and Sepsis
#idsky #IEWiki
www.sciencedirect.com/science/arti...
www.sciencedirect.com/science/arti...

Antibiotic Prescribing for Respiratory Tract Infections in Urgent Care: A Comparison of In-Person and Virtual Settings Little is known about antibiotic prescribing for respiratory tract infections (RTIs) in virtual versus in-person urgent care.

Antibiotic Prescribing for Respiratory Tract Infections in Urgent Care: A Comparison of In-Person and Virtual Settings

#IDSky

See How Many Lives Vaccines Have Saved around the World Vaccines are the first step toward health equity in many parts of the world

Since RFK Jr just got confirmed today, I am taking this chance to share this wonderful @sciam.bsky.social piece on

The Staggering Success of Vaccines

www.scientificamerican.com/article/see-...

Large byline with >100 authors

Diagnostic algorithm

Treatment algorithm for candidemia without end organ involvement

New guidelines for diagnosis and management of candidiasis from ECMM in cooperation with @ishamycology.bsky.social and @asm.org

Led by @olivercornely.bsky.social @rosannesprute.bsky.social with contributions from >100 experts

Author link: authors.elsevier.com/sd/article/S... #IDSky

The all-party parliamentary group on AMR

The All Parliamentary Group on AMR provides a platform to engage with policymakers about AMR. Supported by the British Society for Antimicrobial Chemotherapy, its members are determined to make AMR a political priority for the UK government.

Find out more about their role: tinyurl.com/3zzdrrvt

Could Inoculum Effect in Staph Endocarditis Affect Choice of Antibiotic? An inoculum effect in methicillin-susceptible S aureus infective endocarditis is suspected factor in higher all-cause 30-day mortality with cephazolin treatment than with oxacillin.

An inoculum effect in methicillin-susceptible S aureus infective endocarditis is suspected factor in higher all-cause 30-day mortality with cephazolin treatment than with oxacillin. #IDsky #Medsky

Shorter is greener! 🍃♻️

Unnecessary antibiotics contribute to greenhouse gas emmissions. Want to know how much? 👉🏻 shorturl.at/52wOT

Fantastic point! #IDSky #AMSsky