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Savas Tay

@savastay.bsky.social

University of Chicago Developing molecular/cellular technologies and solving problems in immune signaling.

229 Followers  |  241 Following  |  16 Posts  |  Joined: 17.11.2024  |  2.1059

Latest posts by savastay.bsky.social on Bluesky

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Quantification of extracellular proteins, protein complexes and mRNAs in single cells by proximity sequencing - Nature Methods This work presents Prox-seq that couples sequencing and proximity ligation assay to simultaneously measure extracellular proteins, proteinโ€“protein interactions and mRNA in single cells.

A lot of interesting single cell and spatial proteomics/transcriptomics data applied to immune cells and tissues like the germinal center, looking for a computational postdoc to analyze and integrate!

For reference, see the original prox-seq paper: www.nature.com/articles/s41...

10.06.2025 01:42 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Tay Lab is looking for a computational postdoc to work on proximity sequencing projects. Our new experimental pipelines extend this method to spatially resolved tissue measurements, intracellular proteins, as well as protein modifications like glycosylation, phosphorylation, etc.

10.06.2025 01:41 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Global Science Scholars Postdoctoral Fellowship Program SS-F Apply for the new international postdoctoral fellowship program from the CZ Biohub Network and Stellar Science Foundation.

๐Ÿšจ Funded postdoc opportunities in the U.S. and Japanโ€”spend time abroad! ๐Ÿšจ The Chan Zuckerberg Biohub Network and the Stellar Science Foundation are inviting postdoctoral fellows to apply for the new Global Science Scholars fellowship! ๐ŸŒ๐Ÿ”ฌ

๐Ÿ”— apply now: www.czbiohub.org/program-ssfc...

14.03.2025 02:42 โ€” ๐Ÿ‘ 0    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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A surprising way the immune system remembers โ€“ without antibodies Antibodies always get the credit, but new UChicago Pritzker Molecular Engineering research shows how one type of white blood cell helps the body remember โ€“ and fight โ€“ invaders

Antibodies aren't the only part of the immune system that retain a memory of past infections. Research by @savastay.bsky.social and colleagues at @uchicagopme.bsky.social showed how white blood cells called macrophages change their behavior based on previous threats. pme.uchicago.edu/news/surpris...

04.03.2025 17:37 โ€” ๐Ÿ‘ 3    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Macrophage memory emerges from coordinated transcription factor and chromatin dynamics Wang etย al. combine microfluidic live-cell imaging, chromatin accessibility measurements, and transcriptomics to study how memory is encoded in macrophages. NF-ฮบB activation and chromatin accessibilit...

Do single macrophages remember signals they have previously seen? Our latest paper in Cell Systems: www.cell.com/cell-systems...

11.02.2025 22:04 โ€” ๐Ÿ‘ 15    ๐Ÿ” 6    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

ๅ‹Ÿ้›†้–‹ๅง‹๏ผšๆ—ฅๆœฌใŠใ‚ˆใณ็ฑณๅ›ฝใฎใƒใ‚นใƒ‰ใ‚ฏ็ ”็ฉถๅ“กใ‚’ๅฏพ่ฑกใซใ€ๆ–ฐใŸใชใ€Œใ‚ฐใƒญใƒผใƒใƒซใƒปใ‚ตใ‚คใ‚จใƒณใ‚นใƒปใ‚นใ‚ซใƒฉใƒผใ‚บใƒปใƒ•ใ‚งใƒญใƒผใ‚ทใƒƒใƒ—ใ€ใฎๅฟœๅ‹Ÿๅ—ไป˜ใ‚’้–‹ๅง‹ใ—ใพใ—ใŸใ€‚

09.01.2025 18:27 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Global Science Scholars Postdoctoral Fellowship Program SS-F Apply for the new international postdoctoral fellowship program from the CZ Biohub Network and Stellar Science Foundation.

www.czbiohub.org/program-ssfc...

09.01.2025 18:20 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Quantification of extracellular proteins, protein complexes and mRNAs in single cells by proximity sequencing - Nature Methods This work presents Prox-seq that couples sequencing and proximity ligation assay to simultaneously measure extracellular proteins, proteinโ€“protein interactions and mRNA in single cells.

Tay and Marcus Clark labs are looking for a joint postdoc to help us develop a new 3D spatially resolved proteomic technology based on proximity sequencing, and use it to understand B cell development in the germinal center. Please spread the news! www.nature.com/articles/s41...

03.12.2024 20:16 โ€” ๐Ÿ‘ 5    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

does flu virus in milk infect a human and make them sick?

26.11.2024 18:03 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

yes, and that would almost wholly invalidate the claim of this study

25.11.2024 06:11 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

What is the most daring and extreme thing you have done as an academic? Today, I gave an immunology talk in front of card carrying immunologists ๐Ÿ˜€๐Ÿ˜‚

20.11.2024 23:12 โ€” ๐Ÿ‘ 4    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

will read this!
in my opinion, the best (and maybe only) way to use these atlases for discovery is to build them into a big computer model, they are too large and complex for a human to make sense of

20.11.2024 17:22 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 3    ๐Ÿ“Œ 0

ICQ for sure, but also hotmail

19.11.2024 17:23 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

nice hair bro

17.11.2024 22:01 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1
Apply - Interfolio {{$ctrl.$state.data.pageTitle}} - Apply - Interfolio

We are looking for new Bioengineering and Systems Biology faculty at University of Chicago, please apply and spread the news: apply.interfolio.com/157759

#science #faculty #biology #engineering #academia #technology #research #phd

17.11.2024 18:27 โ€” ๐Ÿ‘ 17    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

so am I.

17.11.2024 18:10 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Hello World!

and yes, please apply!

17.11.2024 16:46 โ€” ๐Ÿ‘ 2    ๐Ÿ” 2    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0

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