Nicolas Parisot

Hi! Florence Hommais, @nicolasparisot.bsky.social , and I are looking for a postdoctoral candidate to investigate the molecular dialogue between three weevil species and their endosymbiotic bacteria #symbiosis! Please see the #post-doc offer for more information. #SymbioSky #Bioinformatics

03.11.2025 11:50 — 👍 11    🔁 12    💬 1    📌 0

Découverte de bactéries architectes - image au microscope électronique

#RP_INRAE De nouvelles pistes de recherche dans la lutte contre les insectes ravageurs avec la découverte de structures membranaires en réseau construites par des bactéries symbiotiques du charançon pour mieux se nourrir.
Étude co-pilotée avec @insa-lyon.fr

➡️ url.inrae.fr/4qLzH1g

29.10.2025 14:21 — 👍 5    🔁 4    💬 0    📌 0

Redirecting

📣 Our latest article is out in Cell @cp-cell.bsky.social:

doi.org/10.1016/j.ce...

A scientific adventure, retold as a 🧵!

29.10.2025 17:09 — 👍 13    🔁 6    💬 1    📌 0

📣 #OurLastPaper is out! And it's a major breakthrough that we're publishing in @cp-cell.bsky.social l: we've discovered architect bacteria that build complex structures to feed themselves better!
#SymbioSky 1/5

29.10.2025 11:48 — 👍 15    🔁 10    💬 1    📌 2

Hi! We are looking for a PhD to work on the cross talk between transposable elements, insects and intracellular bacteria on the bioinformatics side. The PhD would be supervised by @mariefablet.bsky.social and myself along with @nicolasparisot.bsky.social Deadline December 2025! Please share! #tesky

16.09.2025 06:13 — 👍 18    🔁 22    💬 0    📌 2

Congrats to everyone involved in this work! Special thanks to Mariana Ferrarini who analyzed all these data and to Aziz Heddi who led this massive work. And 👏 for my co-authors on #Bluesky @ritarebollo.bsky.social @annazaidmanremy.bsky.social

14.12.2023 09:42 — 👍 2    🔁 0    💬 0    📌 0

The Sitophilus/Sodalis is a very special model in insect #symbiosis. The endosymbiotic bacteria are required for a rapid synthesis of the adult protective cuticle but once the cuticle is achieved, endosymbionts are promptly eliminated.

14.12.2023 09:34 — 👍 0    🔁 0    💬 1    📌 0

Several biological processes are at the center of endosymbiont regulation including immunity, metabolism, Hippo signalling, metal control, apoptosis, and a massive bacterial stress response once the environment becomes hostile.

14.12.2023 09:30 — 👍 0    🔁 0    💬 1    📌 0

We unraveled a #crosstalk between #weevils 🪲 and their endosymbiotic bacteria 🦠 that can be seen as either fully mutualistic or hostile depending on the stage of insect development.

14.12.2023 09:29 — 👍 1    🔁 0    💬 1    📌 0

It was a huge molecular biology 🧪 and #bioinformatics 🧬🖥️ work to decipher their molecular dialogue through 12 stages of insect development using Dual RNA-seq (metatranscriptomics from host and bacteria) and RNA-seq (from symbiotic and aposymbiotc insects)

14.12.2023 09:26 — 👍 0    🔁 0    💬 1    📌 0

Coordination of host and endosymbiont gene expression governs endosymbiont growth and elimination in... Background Insects living in nutritionally poor environments often establish long-term relationships with intracellular bacteria that supplement their diets and improve their adaptive and invasive pow...

📣 #OurLastPaper is out! A huge work to study how #weevils and their #endosymbionts finely tune their gene expression in response to different physiological challenges during insect development 🧪🦠🧬🖥️ #SymbioSky #MicroSky doi.org/10.1186/s401...

14.12.2023 09:16 — 👍 9    🔁 3    💬 1    📌 1