Grateful for this collaboration, combining expertise in hiPSC-derived CNS models with ALD and lipidomics research. Special thanks to my PhD supervisors Vivi Heine, Stephan Kemp, and Marc Engelen, to the lipid expert Yorrick Jaspers, and to all co-authors and everyone who supported this project!
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By profiling the lipidome up to 200 days, we show that organoids undergo dynamic lipid changes during maturation, and that ALD organoids display an early and persistent accumulation of very long-chain fatty acids. Importantly, these lipid alterations mirror those reported in ALD patient brain tissue
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Redirecting
Very happy to share that our organoid lipidomics paper is now out in iScience 🎉
We used human iPSC-derived cortical and spinal cord organoids to study how lipid composition changes during human CNS development and how this is disrupted in X-linked adrenoleukodystrophy (ALD)
doi.org/10.1016/j.is...
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Head Department of Translational Neuroscience, Chair UMC Utrecht Brain Center, neuroscientist, brain circuit development & disease, 🏊♂️, beach🏐 and 🚴♂️ www.jeroenpasterkamplab.com
Neuroscientist (PhD) and half matematician, interested in behavior and neural circuits. Bcn for now, what's coming next?
Molecular Neurobiology unit at Universitat de València. Studying neural stem cell biology and adult neurogenesis. Tweets by lab members. http://farinaslab.com
Postdoc at @hubrechtinstitute.bsky.social @jopkind.bsky.social | PhD at @molgen-emc.bsky.social @hanneslans.bsky.social | DNA repair, chromatin, senescence
Neurobiologist interested in synaptic communication, neuronal networks, neurodevelopmental disorders, stem cell models and much more | Professor Group leader Radboudumc | http://www.nadifkasri-lab.com/Home.html
Developmental neurobiologist and human organoids aficionado. Associate Prof. @USCStemCell. Director @USC CIRM ASCEND Shared Resource Lab. Mama^2. Immigrant 🇮🇹.
https://quadratolab.usc.edu/
https://ascend.usc.edu/
Scientist studying development of embryos and building their models from stem cells. The author of #TheDanceofLife. Warsaw/Oxford/Cambridge/LA.
Studying specializations and vulnerabilities of human brain development
Professor at Stanford & Director of Stanford Brain Organogenesis
Lab: https://pascalab.org
Center: http://www.brainorganogenesis.org
TED: https://go.ted.com/6WJy
Instagram: https://www.instagram.com/sergiu.p.pasca/
neuron-glial interactions, oligodendrocyte lineage, myelin, multi-photon microscopy @CUMedicalSchool
https://www.ethanhugheslab.com/
Neuroscientist. Glial Biologist. Astrocyte enthusiast. Neurodevelopmental lab at Emory University studying the role of glia in health and disease.
www.SloanLab.org
Neuroscientist | Astrocytes | Electrophysiologist interested in Ions, Water and the Brain | Leukodystrophies | Assistant professor @ Amsterdam UMC
Professor at UCSF. Molecular/cellular mechanisms of brain disease. Functional Genomics. Diversity & Inclusion. 🏳️🌈 he/him
Neuroscientist and glial aficionado at NYU Grossman School of Medicine/NYU Langone Health in NYC. Posts in my individual/personal capacity.
My lab is full of awesome people doing amazing stuff - check them out: www.liddelowlab.com
he/him
official Bluesky account (check username👆)
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