RiboCode

@ribochique.bsky.social @veronicathuburn.bsky.social

An early career researcher stands beside a scientific poster, displaying graphs and text, at an academic conference.

An early career scientist explains their poster to an audience at an academic conference.

Several of our RiboCode ECRs recently presented at Translation UK 2025 🧬🤝💬

This was a fantastic opportunity for them to share their research and discuss all things #translation

Read more here 👉 ribocode.org/blog/

Thanks to @biochemsoc.bsky.social for organising such a stimulating meeting.

In York this Saturday?

Tessa Chan (@ribochique.bsky.social) will be waxing lyrical about #ribosomes - the molecular restaurant in our cells - at #SoapboxScience as part of @yorkfestofideas.bsky.social 👩‍🔬🧑‍🔬🔬🗣️💡

Hear from Tessa & other brilliant female and non-binary scientists 👉 tinyurl.com/rut4mkfh

Headshot of Alex Goncalves

Introducing our new senior research technician, Alex Goncalves!

Alex studied at UCL before moving into technical roles at King's College London and Vivian Therapeutics. With a background in human and fly genetics, we are excited for Alex to join the team and get cracking with the RiboCode project!

🎒An inspiring day at Be Curious 2025 🧪

2,200+ people attended this year's festival and we enjoyed taking lots of them on a journey from DNA to proteins. We were amazed by the thoughtful questions posed by visitors of all ages.

Let us know if you would like to try this activity at home!

#outreach

🔔 NEW PAPER: Translational activity of 80S monosomes varies dramatically across different tissues 🔔

The RiboCode team has recently shed light on the translational activity of ribosomes from various Drosophila melanogaster tissues.

Read more on our news page ribocode.org/blog/

Graphical abstract illustrating how viruses can manipulate host cell translational machinery. (1) KSHV begins lytic replication cycle and expresses ORF11, (2) ORF11 recruits EMG1 (and other factors) to the 40S ribosomal subunit for modification and specialisation, (3) The modification causes viral mRNA to be preferentially translated over the host mRNA, (4) Preferential translation of viral proteins leads to increased viral replication and virion production.

🔔 NEW PAPER: EMG1 methyltransferase activity affects ribosome occupancy at KSHV uORFs 🔔

Members of the RiboCode team have contributed to a recent paper that advances our understanding of how viruses can manipulate host cell translational machinery.

Read more on our news page ribocode.org/blog/

👋 Hello to our new followers! 👋

To learn more about the RiboCode project, check out our website ribocode.org

Here you can find out who we are and what we do, as well as exploring our publications and latest activities.

If you have any questions, just get in touch!

#ribosomes #rna #science

To celebrate #BritishScienceWeek, we have created a free resource pack for schools!

The pack contains teaching resources and instructions for a fun hands-on activity.

For more information and to request a free pack, see ribocode.org/resources/

#science #scienceforkids #STEMeducation

Specialized ribosomes: integrating new insights and current challenges | Philosophical Transactions of the Royal Society B: Biological Sciences Variation in the composition of different ribosomes, termed ribosome heterogeneity, is a now well established phenomenon. However, the functional implications of this heterogeneity on the regulation of protein synthesis are only now beginning to be ...

Congratulations @ribocode.bsky.social team on our review published today @royalsociety.org Awesome team work to write this as such a large group. royalsocietypublishing.org/doi/10.1098/...

Philosophical Transactions of the Royal Society B: Biological Sciences: Vol 380, No 1921 Can't sign in? Forgot your password?

Our paper is part of a special issue from Philosophical Transactions of the Royal Society B ⬇️

royalsocietypublishing.org/toc/rstb/202...

Read about different aspects of ribosome heterogeneity and specialisation across species & the latest advances and future direction of the field. (2/2)

Specialized ribosomes: integrating new insights and current challenges | Philosophical Transactions of the Royal Society B: Biological Sciences Variation in the composition of different ribosomes, termed ribosome heterogeneity, is a now well established phenomenon. However, the functional implications of this heterogeneity on the regulation of protein synthesis are only now beginning to be ...

❗NEW PAPER❗

Check out our review on #ribosome heterogeneity and specialisation published today!

We discuss the mechanisms of specialisation, review the latest research and explore how technological advancements will drive the next set of research questions.

doi.org/10.1098/rstb.2023.0377 (1/2)

Tuesday was #InternationalDayOfWomenAndGirlsInScience 👩‍🔬🔬🧫🧬🕷️

Listen to RiboCode's lead PI Julie Aspden (@rna-julie.bsky.social) speaking to @amy-turner96.bsky.social on Proteintech's new pod!

They cover Julie's career so far, leadership, diversity, and how she balances academia w/ family life 🤹‍♀️

Super exciting new paper from three of our brilliant RiboCoders and Nikki Weckman exploring the use of solid-state nanopore in monitoring enzyme digestion pubs.acs.org/doi/10.1021/...

Congrats @nano-chalmers.bsky.social @paoloactis.bsky.social and Emma Thomson!

Artwork inspired by Joy Division 👌

Solid-State Nanopore Real-Time Assay for Monitoring Cas9 Endonuclease Reactivity The field of nanopore sensing is now moving beyond nucleic acid sequencing. An exciting avenue is the use of nanopore platforms for the monitoring of biochemical reactions. Biological nanopores have b...

We cannot join #SMPS4 but hot off the press our nanopore work to monitor CAS9 reactivity and its off-target effects. pubs.acs.org/doi/10.1021/...

Thanks for the shout out, Ian!

Three members of the RiboCode team stand beside an exhibit in an indoor garden.

🍃🎐The Ribosome Wind Garden 🎐🍃

Read about our collab with artist Christopher Jarratt at Sheffield's Festival of the Mind this year

ribocode.org/blog/

Happy to share the website of RiboMod2025, the "Conference on Ribosomal RNA modifications and snoRNAs" in Bologna June 12-13, 2025 is up at events.unibo.it/ribomod2025
Stay tune for more infos!
#RNA #Ribosome #snoRNA #Eiptranscriptomics

Job Opportunity at University of Leeds: Senior Research Technician in Gene Expression Are you an experienced technician looking for a challenge?  Do you have a background in gene expression and RNA biology?  Do you have experience in using model organisms? Do you want to further your c...

Come and join RiboCode!

Are you interested in understanding the mechanisms of mRNA translation? Do you have experience using D. melanogaster? Would you like to join an interdisciplinary team?

If so, apply for our Senior Research Technician role @universityofleeds.bsky.social

shorturl.at/ytnrA