Lekshmi Santhosh MD MAEd (she/her)

Love celebrating our amazing @ucsfmedicine.bsky.social IM residency Fellowship Match!! So proud of our residents!! 🎉🎉🎊🎊👏🏾👏🏾❤️❤️💐💐🥳🥳🥂🥂

Justin is amazing and you all are so lucky to have him! Congrats on an outstanding match! 👏🏾🎊🎉

I ended up going meal-iodosis to support #publichealth!

Ahhh what team did #PCCM land in, @shematologist.medsky.social? Submitting my receipts now! GO #HCWvsHunger!!

1 diagnose and treats 2 kidvengers 3 mealiodosis 4 brain docs 5 Isla of misfit toys 6 blades n bougies 7 I’m generous 8 PMR 9 urine it to win it 10. Rx hunger

The #HCWvsHunger leaderboard has changed up again!

Five hours left to donate to your favorite anti hunger organization and log that donation at HCWvsHunger.org!

Anything can happen in these last hours…

Colorful model showing Block 2.0 + Threads in a sample resident schedule - Figure 1 in the Paper

How do we train well-rounded IM docs & support individualized career paths? Meet Block 2.0 & Inpatient Threads, 2 #MedEd #Innovations from @ucsanfrancisco.bsky.social Internal Med Residency. Read more from our team in @journalgim.bsky.social: link.springer.com/article/10.1...
@bobwachter.bsky.social

The U.S. Is Funding Fewer Grants in Every Area of Science and Medicine A quiet policy change means the government is making fewer bets on long-term science.

“Thousands of very competitive projects in areas like cancer, diabetes, aging, neurological disorders and public health improvements most like went unfunded in 2025.
Similarly, at the National Science Foundation, the roughly 3,000 fewer new grants encompassed reductions to every area of science”

They need a ventilator to stay alive. Getting one can be a nightmare Few nursing homes can care for people who need help breathing with a ventilator because of ALS and other conditions. Insurers often deny payment for the best at-home machines, and innovative solutions are endangered by Medicaid cuts.

Few nursing homes can care for people who need help breathing with a ventilator because of ALS and other conditions. Insurers often deny payment for the best at-home machines, and innovative solutions are endangered by Medicaid cuts.

'Nobody wants to come': What if the U.S. can no longer attract immigrant physicians? Immigrants make up a significant proportion of all the country's doctors. New policies are making it harder and less appealing for foreign-born physicians to come to the U.S.

Immigrants make up a significant proportion of all the country's doctors. New policies are making it harder and less appealing for foreign-born physicians to come to the U.S.

New paper 📣 In @journalgim.bsky.social, Drs. Butler, Velazquez Manana, @laurahuppert.bsky.social, Hsu, Babik, Trejo & I explore how IM residents make subspecialty career choices w/ a #qualitative approach. Read here! rdcu.be/eQ9Y6 Need #mentorship & role models to improve women & UIM representation!

Nursing is no longer counted as a 'professional degree' by Trump admin The Department of Education has excluded nursing as a "professional degree" program as it implements various changes to student loans.

According to the Trump admin, nursing isn’t a profession so they won’t qualify for student loans 🤬

We’re barely recovering from the last RN shortage and they want to create another one 😫

Literally zero patients survive the ICU without outstanding RN care.

www.newsweek.com/nursing-not-...

The ATS applauds the Tiburon town council for passing the strictest, most comprehensive tobacco and nicotine sales ban in the country. We encourage other cities to do the same to ensure the health of their populations and help people breathe better.
 
Read more: www.sfgate.com/local/articl...

Clinical Trials Affected by Research Grant Terminations at the National Institutes of Health This cross-sectional study summarizes the number of trials with terminated grants from the National Institutes of Health (NIH) and calculates the proportion of affected trials among those with previou...

Important new analysis identifying the scope of clinical trials disrupted because of NIH shenanigans.

> 74 thousand trial participants affected

jamanetwork.com/journals/jam...

1/4

Thank you, OHSU PCCASM Division for an amazing visit! So amazing to connect with colleagues & mentors, learn from new folks & old friends #peermentorship, and brainstorm about possible collaborations. Thanks Drs. Drake, Gause, & Hubel for a lovely visit to Portland! 🫁🙏 @terrihough.bsky.social

American Thoracic Society | Elizabeth A. Rich, MD Award The American Thoracic Society is the world's leading medical society dedicated to accelerating the advancement of global respiratory health through…

Nominations are open for the Elizabeth A. Rich, MD, Award. The award recognizes an outstanding woman who has made contributions in pulmonary, critical care, & sleep medicine, and will be presented at the #ATS2026 Women’s Forum.

Nominations close Nov. 24:

Happy one year off Twitter to all who celebrate

Congratulations to all the Democratic candidates who won tonight. It’s a reminder that when we come together around strong, forward-looking leaders who care about the issues that matter, we can win. We’ve still got plenty of work to do, but the future looks a little bit brighter.

1/ Open enrollment for Obamacare (ACA) kicked off this weekend, during which more than 20 million families will shop for health insurance coverage. There's some sticker shock though: prices are up ~30% this year if tax credits aren’t extended. Here’s what else is happening in #publichealth 👇

California – this Election Day, vote yes on Prop 50.

California’s Prop 50 says that if Republicans are going to abuse the system to try and hang onto power, we’re going to counteract that abuse and create a level playing field in the midterm elections.

Make a plan to vote yes on Prop 50.

The scariest thing you can do this Halloween season is forget to vote. 🎃👻

Yes, Halloween is the deadliest day of the year for child pedestrians—great advice from @mcbazacophd.bsky.social

(It’s also our kid’s birthday)

Pedestrian Fatalities Associated With Halloween in the United States This study examines 42 years of National Highway Traffic Safety Administration data to establish whether Halloween is associated with an increased rate of pedestrian fatalities.

Traffic fatalities for kids rise on Halloween. Drive carefully.

Study of 42 years of Halloweens and 1 ,580,608 traffic crashes reveals relative risk of a pedestrian fatality is 43% higher on Halloween compared with control evenings. A typical Halloween results in 4 additional pedestrian deaths.

Check out the collaborative learning series of seven modules on ATS Ed+ for clinicians treating patients with serious illnesses, made by the ATS and CAPC. Earn CME! #pallipulm @anandiyermd.bsky.social @donsullivan.bsky.social @pallipulm.bsky.social

Read more: atsedplus.thoracic.org/capc/palliat...

ATS Scholar is accepting applications for our Editorial Fellowship program

Learn more here: www.atsjournals.org/announcement...

📅 Deadline: October 31, 2025
@atscommunity.bsky.social #medsky

🎃 Don't be scared! You still have time to submit abstracts for ATS 2026!

The ATS is accepting scientific abstracts and case reports on all aspects of respiratory disease, critical care, and sleep medicine for ATS 2026

Deadline is Nov. 5, 2025. Submit today: conference.thoracic.org/program/call...

Key points from Lekshmi Santhosh sepsis update at #UCSFMHP2025. Remember: give fluids early in shock but de-escalate quickly once hemodynamically stable.
Hot off the presses: @NEJM study showing that many ICU sepsis patients don't benefit from arterial lines nejm.org/doi/full/10....

It's always a thrill to welcome > 500 hospitalists to my annual
UCSF Management of the Hospitalized Patient conference in SF. I'll tweet 1-2 take-home points from talks over the next few days. Below: Lekshmi Santhosh on sepsis updates (incl. data hot off presses)
#UCSFMHP2025

Yes the best line of the whole piece that truly sums it up! 👏🏾👏🏾

a man with a beard is holding a stethoscope around his neck and saying lucky lucky me . Alt: Noah Wyle from The Pitt (a man with a beard) is holding a stethoscope around his neck and saying lucky lucky me .

OBVI the new #ESICM #LIVES2025 #sepsis trials drop the day before my sepsis lecture 😆 Excited to read/digest/translate for #MHP2025 tomorrow!

JAMA cover: "Capillary Refill Time in Sepsis—Searching for the Holy Grail" by Flavia R. Machado, MD, PhD; Matthew W. Semler, MD, MSc. Published online October 29, 2025. Editorial discusses early goal-directed therapy for septic shock.

💬 Editorial: While capillary refill time shows promise for early #SepticShock management, integrating it into broader, multimodal resuscitation strategies remains key to improving outcomes.

#LIVES2025 @esicm.bsky.social

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