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Charlie Allen

@charlieallen.bsky.social

she/they | tech in the Buchwalter Lab at UCSF studying the nuclear periphery | California Community College alum

108 Followers  |  231 Following  |  19 Posts  |  Joined: 31.07.2023  |  2.0215

Latest posts by charlieallen.bsky.social on Bluesky

i will say that looking up the description for my signals and systems courses and trying to decide how to classify it is preferable to trying to deal with a request for an under-specified bespoke gpa calculation

04.11.2025 16:08 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

would appreciate if my union would not send me political spam texts addressed to my dead mom

04.11.2025 01:54 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

or really any kind of tranny

04.11.2025 00:32 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

Nobody wants a sad tranny in their grad program

03.11.2025 23:00 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

Or maybe I should just give up on this idea

03.11.2025 16:45 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
Preview
Every Trans Suicide Is A Murder By Those In Power News came this week that transgender athlete and student Lia Smith took her life at just 21 years of age.

1. This week, news emerged that former trans athlete, student at Middlebury, and advocate for trans rights, Lia Smith, was found dead.

Her death was ruled a suicide.

But I argue that it's not only a suicide. Every trans suicide is a murder by those in power.

Subscribe to support my journalism.

29.10.2025 16:19 β€” πŸ‘ 2725    πŸ” 654    πŸ’¬ 28    πŸ“Œ 44

Trying and failing how to do everything complete alone

01.11.2025 01:10 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

No support, no friends

01.11.2025 01:07 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

just a sad ugly tranny

01.11.2025 01:06 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

maybe there’s just no place in science for me

01.11.2025 01:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0

How hard is it for ucsf to display the correct reference ranges for lab tests?

31.10.2025 00:05 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
NYT Magazine headline β€œβ€˜I'm on Fire': Testosterone Is Giving Women Back Their Sex Drive - and Then Some
There is no F.D.A.-approved testosterone product for  women. Insurance won't cover it. Many doctors won't prescribe it. It's become a cultural phenomenon.”

NYT Magazine headline β€œβ€˜I'm on Fire': Testosterone Is Giving Women Back Their Sex Drive - and Then Some There is no F.D.A.-approved testosterone product for women. Insurance won't cover it. Many doctors won't prescribe it. It's become a cultural phenomenon.”

when trans people take HRT to feel normal: β€œlook at these depraved sex freaks performing their sick fetish in public, we should bully them out of existence”

when cis ppl take HRT so they can fuck real good:

22.10.2025 18:14 β€” πŸ‘ 9540    πŸ” 2797    πŸ’¬ 81    πŸ“Œ 209

put it off for long enough already, no real cost but stress

20.10.2025 23:33 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

might as well do some last minute phd applications this cycle

20.10.2025 23:11 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 1    πŸ“Œ 1

I'm so glad you said this, because about 30 seconds ago, I published a newsletter piece detailing how conservatives have dump-trucked through all of the previously established common sense, nuanced, compromise positions on trans rights to get here: burns-notice.ghost.io/what-would-t...

29.09.2025 16:03 β€” πŸ‘ 975    πŸ” 254    πŸ’¬ 16    πŸ“Œ 20

can the hayward fault wait another hour next time? this is a little too early to wake up

22.09.2025 10:27 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

strongest earthquake i can remember in a long time

22.09.2025 10:07 β€” πŸ‘ 6    πŸ” 1    πŸ’¬ 1    πŸ“Œ 0

As usual with this issue, Harris is calling for a compromise that already exists. Every sporting body has standards for how long athletes must be on hormones before they can compete as women.

The problem isn’t that we’re ignoring β€˜reasonable concerns,’ the problem is that republicans are lying.

20.09.2025 08:10 β€” πŸ‘ 6982    πŸ” 1782    πŸ’¬ 126    πŸ“Œ 108

you'd think 'how do we optimize hrt to best achieve patient goals' would be way more studied than it actually is. instead we largely have endocrinologist folk wisdom and anecdotes

08.09.2025 00:52 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

requiring applicants to not only manually re-enter most of their transcript but also track down a course catalog to copy and paste course descriptions for dozens of courses from years to decades ago is absurd

04.09.2025 17:19 β€” πŸ‘ 3    πŸ” 0    πŸ’¬ 0    πŸ“Œ 1

wish i could just spend all day cloning

04.09.2025 14:10 β€” πŸ‘ 0    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I will grudgingly admit that it is occasionally nice to spend a sunday morning reading Nevada and watching movies instead of being in the cell culture room

24.08.2025 17:47 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0

I'm happy people can read the final version of this paper! See what happens when we detach heterochromatin from the nuclear periphery in mouse stem cells:

23.07.2025 01:21 β€” πŸ‘ 5    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0
Video thumbnail

And yep - we found that the nuclear membrane protein LAP2b cooperates with lamin B1 to maintain nuclear integrity. When both are depleted, we see lamina defects and nuclear ruptures that look like this (cyan is nuclear lamina, magenta is nuclear integrity reporter): (5/n)

21.07.2025 17:49 β€” πŸ‘ 3    πŸ” 1    πŸ’¬ 2    πŸ“Œ 0
Preview
Lamin B1 and LAP2Ξ² resist cytoskeletal force to maintain lamin A/C meshwork organization and preserve nuclear integrity | Molecular Biology of the Cell The nuclear lamins are extremely long-lived proteins in most cell types. As a consequence, lamin function cannot be effectively dissected with temporal precision using standard knock-down approaches. ...

The nuclear lamina strengthens the nucleus and organizes the genome. So what happens when you acutely degrade it in living cells? Not what we thought! (1/n)
www.molbiolcell.org/doi/10.1091/...

21.07.2025 17:46 β€” πŸ‘ 24    πŸ” 12    πŸ’¬ 2    πŸ“Œ 0

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