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Christopher Snow

@cdsnow.bsky.social

Professor at Colorado State University. Previously MIT Chemistry (Tidor), Stanford Biophysics (Pande), Caltech Chemistry and Chemical Engineering (Arnold). Interests: Protein Engineering, Computational Protein Design, ML, Biomolecular Crystals

611 Followers  |  343 Following  |  5 Posts  |  Joined: 16.11.2024  |  1.785

Latest posts by cdsnow.bsky.social on Bluesky

I’ll be there and would be enthusiastic to chat Bindcraft, crystals, etc.

28.06.2025 03:16 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 1    πŸ“Œ 0
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Making intrabodies from antibodies just got easier! Learn how we made 𝟭𝟡 intrabodies to bind and light up peptides and histone modifications in live cells. And thanks to Academia, all sequences are freely available. (video credit: Yuko Sato @YukoSatoT2) (1/15)
www.biorxiv.org/content/10.1...

12.02.2025 06:28 β€” πŸ‘ 221    πŸ” 96    πŸ’¬ 12    πŸ“Œ 16

Very pleased with this ProteinMPNN-based collaboration that ballooned to encompass an impressive number of redesigned proteins for intracellular biomolecular recognition! www.biorxiv.org/content/10.1...

11.02.2025 23:18 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0
Protein cartoon, mostly depicted in blue for very high confidence (pLDDT) despite extended N-terminus as it exists in a domain swap...

Protein cartoon, mostly depicted in blue for very high confidence (pLDDT) despite extended N-terminus as it exists in a domain swap...

AlphaFold3 Cautionary Tale: We deposited multiple PDB entries for β€œCJ,” a binding protein that domain swaps when crystallizing. Local AF3 in the presence of decane gives the domain swapped form with high confidence extended N-terminus (4/5 models). Yikes! Perhaps template-driven false confidence...

25.11.2024 20:01 β€” πŸ‘ 4    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Engineering with Artificial Intelligence Assistant/Associate Professor - All Fields The Walter Scott, Jr. College of Engineering at Colorado State University announces a College-wide search for six new faculty members who use artificial intelligence (AI) as a key component of their r...

The W Scott College of Engineering has announced a cluster of 10 new openings for tenure track professors in Engineering with Artificial Intelligence. We'd love for you to join our beautiful and supportive community! Please repost.

jobs.colostate.edu/postings/152...

22.11.2024 14:18 β€” πŸ‘ 1    πŸ” 1    πŸ’¬ 0    πŸ“Œ 0

Wouldn't mind being in Pack 2 or a future one -- we're doing a variety of ML-enabled protein engineering projects from intracellular binding proteins to biomolecular crystal engineering.

20.11.2024 18:54 β€” πŸ‘ 1    πŸ” 0    πŸ’¬ 0    πŸ“Œ 0
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Amino Acids by @entertainingchurchchoir073 | Suno 1960s bossa nova song. Listen and make your own with Suno.

Hi folks, to those teaching courses where it is useful to know the one letter amino acid code, I used Suno to make a mnemonic song (Bossa nova style...)
suno.com/song/8ce2f2e...

17.11.2024 21:10 β€” πŸ‘ 5    πŸ” 2    πŸ’¬ 0    πŸ“Œ 0

@cdsnow is following 20 prominent accounts