Michal Kolář

A group of people walking on a path through meadows, with forests in the background. Hilly environment, gray clouds.

Hiking time with Hlouchova lab during our GACR project retreat in Jachymov. A lot of discussions on protein-RNA interactions under probiotic conditions🦠

🥇 Václav Verner (PORG) won 2nd place in the world
🥈 Matěj Pěnička (Gymnázium Nad Alejí)
🥈 Ondřej Michal (Gymnázium Botičská)
🥉 Adam Horák (Gymnázium Hranice)

Annual reports - Czexpats in Science Annual report 2024 2024 was a year of significant milestones for Czexpats in Science. We greatly expanded our community-building activities, including our largest Christmas Conference and six internat...

🗣️ We are pleased to announce that our 2024 Annual Report is out and for the first time in English! ➡️ czexpats.org/en/about-us/...

Our first publication output within the Czech Science Foundation project (25-15428S) about the prebiotic role of peptides in the emergence of the #ribosome.

A scheme of chemico-biological evolution of protein-RNA interactions. It started about 4.5 billion years ago with prebiotic monomers, went through peptides, oligonucleotides, and simple complexes, reaching proteins and RNA at about 4-3.7 billion years ago.

New publication out on the evolution of protein-RNA interactions. Put together with Klára Hlouchová (@sciencecharles.bsky.social) during a lovely Czech spring.

www.sciencedirect.com/science/arti...

To be fair, the organisers have diluted the poster panels over the days👏🏻 So visit the side hall as well, there are many great posters.

Poster is up and I've tried hard to match my t-shirt with the poster title. We're in the front hall, No. 24. Visit us, there's more air than around the posters in the side hall🫠

#EBSA

My temporary office at #EBSA in Rome.

My flight to Rome delayed by 12 hours. Saying goodbye to day 1 of the #EBSA conference and I'm hoping to make it for day 2!

The same poster but cut in halves vertically, so when rolled down it fits to a luggage.

A scientific poster about ribosome simulations. In a viridis colors scale from yellow through green and blue to dark violet.

Heading to #EBSA in Roma and packing my poster to a luggage. Not a fan of poster tubes 🫣

Full text arxiv.org/abs/2503.21357

For Czech readers: The Prague administration has once again shown its incompetence - this time by failing to manage basic demographic data. As a result, young students are paying the price when trying to get into high schools. www.eduin.cz/clanky/nafou...

English-speaking colleagues welcome!

Summer’s around the corner, and if you're in the mood for a break from the lab or the office, pop by Cafe Prostoru on June 10 to grab a beer and have a chat 😎

If you’re planning to join us, let us please know via the link above 🙏

I'll be there😎

Ceny Czexpats in Science

For Czech readers: Some of the brightest Czech minds who made it to the finals of the @czexpats.bsky.social Award have short research summaries featured in the latest issue of @vesmir.bsky.social

vesmir.cz/cz/casopis/s...

We are pleased to announce that the next speaker in the ProSE seminar series will be Dr. Klara Hlouchova with a talk on "Protein Structure Before LUCA"
May 13, 4PM CET
Registration link: tinyurl.com/prose-seminar4
Please share!

Our research group studies #ribosomes. Our favorite region of interest is the ribosomal tunnel. We realized that it has been missing a Wikipedia page until now, so we decided to create one. Read, edit, enjoy👇

en.wikipedia.org/wiki/Ribosom...

🌟 #PI_Forum Brno #5: Academic Leadership: The Big Picture is ahead!
How does one lead a team vs. an institution?
Join Irena Radová (MUNI) & Jiří Přibáň (Constitutional Court) to explore leadership in academia and beyond.
🗓️ 13 May 2025
📍CEITEC MU, room 211. Register: czexpats.org/en/udalost/p...

12th PI forum by @czexpats.bsky.social, today about science communications with @pavlahubalkova.bsky.social.

Pink sakura trees in full bloom on front of VŠCHT Praha.

Sakuras in front of @vschtpraha.bsky.social

Happy Easter!

Zeptej se vědce Dotaz 1191 Pomáhá vědcům pobyt na jiném pracovišti? 🌍 Proč vědci často zabalí kufry a frčí dělat vědu do zahraničí? Je to vůbec k něčemu dobré? ❓Na otázku od iniciativy Czexpats in Science * nám odpoví Radim👇

🌍 Proč vědci často zabalí kufry a frčí dělat vědu do zahraničí? Je to vůbec k něčemu dobré?
❓Na otázku od iniciativy Czexpats in Science * nám odpoví Radim👇

Lovely indeed. Where is it?

Why does it matter? Uncovering ribosome origins might one day help us tackle antibiotic resistance.
Fundamental science, fascinating questions, and a bit of time travel. 🌍🧬

📖 Read the full interview on the UCT Prague website: www.vscht.cz/press/interv...

Tomato?🫣

Due to the imbalance of water-RNA and water-water interactions. Water is too polar and/or RNA too hydrophobic.

Joe et al. have a fresh preprint on the MARTINI simulations of the #ribosome.

arxiv.org/abs/2503.21357

Inside arXiv—the Most Transformative Platform in All of Science Modern science wouldn’t exist without the online research repository known as arXiv. Three decades in, its creator still can’t let it go.

Nearly 35 years ago, Paul Ginsparg created arXiv, a digital repository where researchers could share their latest findings before they had been systematically reviewed or verified. If arXiv stopped functioning, scientists would suffer an immediate and profound disruption.

ribosome

now we will move with bacterial ribosome by coarse grain simulations with Josef Cikhart from @mhko.bsky.social group at @vschtpraha.bsky.social

Job alert ! I am looking for a postdoc to work on "computational investigation of ion-effects in ribozyme catalysis" to work with me in Paris (France). 1-year contract funded by @agencerecherche.bsky.social, with possible 2nd year in collab. with P. Jungwirth @iocbprague.bsky.social #compchem #RNA

Structurally heterogeneous ribosomes cooperate in protein synthesis in bacterial cells - Nature Communications Cells can simultaneously produce structurally dissimilar ribosomes, suggesting functional specialization of distinct ribosome populations. Here, the authors show that distinct ribosomes cooperate rath...

Here we unexpectedly find that the ribosomal protein S20/L26—identified at the dawn of ribosome research but later deemed a biochemical artifact—is indeed a genuine component of the large ribosomal subunit. More on this ribosome content variation is here: www.nature.com/articles/s41...

Posters of Aneta and Ondra at XXI Discussions in Nové Hrady are ready to welcome visitors. Come and learn about peptide deformylase and protoribosome.