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Roger Cruz-Vera

@cruzveralab.bsky.social

Associate Professor University of Alabama in Huntsville. I have studied E. coli ribosomes and their products and regulations throughout my academic life. #Ribosomes #biofilms #tRNA https://sites.google.com/a/uah.edu/cruz-vera-s-lab/home

197 Followers  |  185 Following  |  39 Posts  |  Joined: 01.12.2023  |  2.3768

Latest posts by cruzveralab.bsky.social on Bluesky

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Fire RFK Jr. NOW! Since he was confirmed in February 2025, RFK Jr. has put the health of Americans at risk. Under his direction, the Centers for Disease Control and Prevention (CDC) director, Dr. Susan Monarez, was fir...

This cause is close to my heart - please sign: sign.moveon.org/petitions/fi...

26.09.2025 14:00 โ€” ๐Ÿ‘ 3    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

''including ORFs within tRNA loci.'' ๐Ÿคท๐Ÿปโ€โ™€๏ธ๐Ÿง study detects significant ORF hits at 10 distinct tRNA loci under high chloramphenicol selection ๐Ÿฆ 

27.09.2025 07:20 โ€” ๐Ÿ‘ 8    ๐Ÿ” 4    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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RNA modifications digest Summer 2025 Bimonthly newsletter: RNA modifications and related topics, mostly in bacteria. Summer 2025, first issue!

๐Ÿฆ  Launching a bimonthly digest on RNA modifications and related topics in bacteria!๐Ÿคฉ First issue: Summer 2025. Shared here + by email, future ones will be quicker reads! ๐Ÿ˜… #rnasky #microsky #ribosome Subscribe and share if you are interested! rnamodifupdates.substack.com/p/rna-modifi...

15.08.2025 09:30 โ€” ๐Ÿ‘ 17    ๐Ÿ” 11    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Ribosome transfer via tunnelling nanotubes rescues protein synthesis in pancreatic cancer cells Background: Pancreatic ductal adenocarcinoma (PDAC) is considered as one of the deadliest types of cancer. Tunnelling nanotubes (TNTs) are thin, membranous, intercellular communication structures obse...

Our significantly expanded preprint is out. In it we show that pancreatic cancer cells can transfer ribosomes via tunnelling nanotubes and rescue protein synthesis when co-cultured with cells with impaired ribosomal biogenesis.
๐Ÿงช
(Includes some #bayesian #rstats inspired by @rmcelreath.bsky.social)

06.08.2025 07:56 โ€” ๐Ÿ‘ 25    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
Portrait of Rachel Green, an RNA biologist at Johns Hopkins University

Portrait of Rachel Green, an RNA biologist at Johns Hopkins University

โ€œWhat a [sunburned] cell is trying to do is make decisions about whether to live or die based on how damaged the DNA isโ€ฆ but amazingly, itโ€™s the RNA that signals that. Thatโ€™s the remarkable observation.โ€ โ€” Rachel Green, biologist at Johns Hopkins University.
www.quantamagazine.org/rna-is-the-c...

04.08.2025 20:04 โ€” ๐Ÿ‘ 79    ๐Ÿ” 23    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 3
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Structures of Naked Mole-Rat, Tuco-Tuco, and Guinea Pig Ribosomes: Is rRNA Fragmentation Linked to Translational Fidelity? Ribosomes are central to protein synthesis in all organisms. Among mammals, the ribosome functional core is highly conserved. Remarkably, two rodent species, the naked mole-rat (NMR) and tuco-tuco dis...

nam02.safelinks.protection.outlook.com?url=https%3A...

06.08.2025 11:27 โ€” ๐Ÿ‘ 9    ๐Ÿ” 4    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 0
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Check out our new preprint on the discovery of a molecular switch in NAC that mediates nascent chain sorting on the ribosome and prevents mitochondrial protein mistargeting by SRP. A great collaboration with the Shan Lab @Caltech and the Qi Lab @UVA: www.biorxiv.org/content/10.1...

01.08.2025 15:27 โ€” ๐Ÿ‘ 82    ๐Ÿ” 28    ๐Ÿ’ฌ 4    ๐Ÿ“Œ 2
underwater cartoon scene, with pink algae on the bottom and the text: join us! postdoctoral research in algal (photo)physiology. Deadline 18 September 2025

underwater cartoon scene, with pink algae on the bottom and the text: join us! postdoctoral research in algal (photo)physiology. Deadline 18 September 2025

**Join us!**

2 year #postdoc in algal (photo)physiology

Multidisciplinary project as part of the @icelabumu.bsky.social Postdoc Programme

๐Ÿ”— heidiburdett.wordpress.com/2025/06/27/p...
๐Ÿ“† 18 September 2025
๐Ÿ“ @umeauniversitet.bsky.social, Sweden

@umeaunimarine.bsky.social
๐Ÿฆ‘๐Ÿงช๐ŸŒŽ

27.06.2025 11:56 โ€” ๐Ÿ‘ 11    ๐Ÿ” 9    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

We have!

27.06.2025 12:43 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Story about EMCV IRES interactions with the ribosome:
www.biorxiv.org/content/10.1...

12.06.2025 22:05 โ€” ๐Ÿ‘ 12    ๐Ÿ” 4    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Time for Episode 95 of #MattersMicrobial! This time, Dr. Tory Hendry of Cornell University joins the #QualityQuorum to discuss aphids, symbiosis, and fluorescent bacteria. Please spread the #GoodMicrobialWord? microbe.tv

youtu.be/i9xoWApANNM?...

13.06.2025 16:28 โ€” ๐Ÿ‘ 11    ๐Ÿ” 6    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

๐ŸŽ™๏ธI am thrilled to share this episode of #MattersMicrobial hosted by @markowenmartin.bsky.social.
@symbionticism.bsky.social and I talk about One Health Microbiome Sciences and what is next for the microbiome research field! ๐Ÿฆ ๐ŸŒ

09.06.2025 17:17 โ€” ๐Ÿ‘ 8    ๐Ÿ” 4    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

We are recruiting ๐Ÿ‘‡ #PhD #INPST

07.06.2025 03:26 โ€” ๐Ÿ‘ 14    ๐Ÿ” 7    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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MI/25/33 - Postdoctoral Scientist Systems Oncology Group | Cancer Research UK Manchester Institute Add brief description here

We are looking for a postdoctoral fellow to come work with us: www.cruk.manchester.ac.uk/career/mi-25... Please reach out

07.06.2025 09:57 โ€” ๐Ÿ‘ 10    ๐Ÿ” 11    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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Control of seed-to-seedling transition by an upstream open reading frame in ABSCISIC ACID DEFICIENT2
www.pnas.org/doi/full/10....
#plantscience

07.06.2025 10:27 โ€” ๐Ÿ‘ 16    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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UAH | News | The University of Alabama in Huntsville

This could also be a fun interview. They are working on resolving biofilms at the International Space Station. www.uah.edu/news/items/u...

06.06.2025 17:00 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0
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A bacterial regulatory uORF senses multiple classes of ribosome-targeting antibiotics An upstream open-reading frame in Escherichia coli regulates expression of the downstream genes in response to diverse translation stresses.

A bacterial regulatory uORF senses multiple classes of ribosome-targeting antibiotics
elifesciences.org/articles/101...

03.06.2025 07:05 โ€” ๐Ÿ‘ 14    ๐Ÿ” 8    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

All of NIH funding to Northwestern University is frozen. This pause includes noncompeting approved funding, new and competing grants with fundable scores. No reimbursements for money already spent have been received since March. This situation is rarely reported so please Please get the word out!

23.05.2025 17:56 โ€” ๐Ÿ‘ 2267    ๐Ÿ” 1325    ๐Ÿ’ฌ 34    ๐Ÿ“Œ 31

Enrichment, great work!

23.05.2025 13:49 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Marie Curie fellowship, post-doc hosting oppotunity in my lab. MSCA Post-doctoral Fellowship at IBPC Paris on RNA modifications in bacteria (FRANCE) ๐Ÿฆ ๐Ÿ’ซ euraxess.ec.europa.eu/jobs/hosting...

21.05.2025 16:19 โ€” ๐Ÿ‘ 15    ๐Ÿ” 26    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 2
You Can Fix Your DNA... Starting Now (feat. Nobel Prize Winner)
YouTube video by Cleo Abram You Can Fix Your DNA... Starting Now (feat. Nobel Prize Winner)

Jennifer Doudna @jenniferdoudna.bsky.social @doudna-lab.bsky.social speaks with Cleo Abrams on the history and future of #CRISPR ๐Ÿงฌ. Watch here: youtu.be/0OXaanDHENI?...

19.05.2025 16:16 โ€” ๐Ÿ‘ 11    ๐Ÿ” 5    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

Really excited to share our resource and analysis of AlphaFold-predicted monomers and homodimers across viruses and phages. Project driven by fab PhD student @rodai.bsky.social and with our great collaborators Joana Pereira @joanampereira.bsky.social and @ninjani.bsky.social

19.05.2025 06:37 โ€” ๐Ÿ‘ 67    ๐Ÿ” 33    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 1

ooo this looks fun, and in โค๏ธYorkโค๏ธ

19.05.2025 07:16 โ€” ๐Ÿ‘ 4    ๐Ÿ” 1    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Translational activity of 80S monosomes varies dramatically across different tissues Abstract. Translational regulation at the stage of initiation can impact the number of ribosomes translating each mRNA molecule. However, the translational

Delighted to share paper on translational activity of 80S monosomes across different tissues in ๐Ÿชฐ in @narjournal.bsky.social thanks to fabulous team Albert Blandy Tayah Hopes Elton Vasconcelos @amy-turner96.bsky.social Bulat Fatkhullin Michaela Agapiou Juan Fontana academic.oup.com/nar/article/...

14.05.2025 16:03 โ€” ๐Ÿ‘ 44    ๐Ÿ” 21    ๐Ÿ’ฌ 2    ๐Ÿ“Œ 1
Portail Emploi CNRS - Offre d'emploi - Postdoctoral Researcher (M/F) in Structural Biology

A 2-year postdoctoral position is available in the group "RNA Biogenesis, Architecture and Interactions," led by Carine Tisnรฉ at the Institut de Biologie Physico-Chimique (IBPC), Paris.

RNA modification landscape of V. cholerae

Great lab, great location & great PI

emploi.cnrs.fr/Offres/CDD/U...

13.05.2025 07:04 โ€” ๐Ÿ‘ 8    ๐Ÿ” 14    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0
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Detecting ribosome collisions with differential rRNA fragment analysis in ribosome profiling data Abstract. It has become clear in recent years that ribosomes regularly stall during translation. Such translation impairment has many causes, including exp

New paper from the lab! Want to know if there is a difference in ribosome collisions between your samples? We show that you can detect this in the rRNA reads in your ribosome profiling data.

academic.oup.com/nargab/artic...

08.05.2025 11:32 โ€” ๐Ÿ‘ 39    ๐Ÿ” 19    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 2
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m6A alters ribosome dynamics to initiate mRNA degradation m6A is a potent inducer of ribosome stalling and collisions that trigger YTHDF-mediated mRNA degradation, a process that highlights the ribosome as a critical sensor linking translation dynamics to m6...

m6A alters ribosome dynamics to initiate mRNA degradation: Cell www.cell.com/cell/fulltex...

09.05.2025 09:48 โ€” ๐Ÿ‘ 0    ๐Ÿ” 2    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

on control of Gene Transfer Agents (domesticated phages) in Caulobacter.
Insights on how Borrelia spp co-exist with their semi-domesticated cp32/PhiBB prophages?
#MicroSky

09.05.2025 11:55 โ€” ๐Ÿ‘ 6    ๐Ÿ” 1    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

The USA is fourth; 20% of the USA population is Catholic (68 million). Clearly, as you will discuss, there is political stuff involved here. I have the feeling that we are still seeing colonialism.

08.05.2025 23:47 โ€” ๐Ÿ‘ 0    ๐Ÿ” 0    ๐Ÿ’ฌ 0    ๐Ÿ“Œ 0

Brazil has a population of 123 million Catholics (70% of its population), followed by Mexico and the Philippines (80% of their population). None of these countries has had a Pope.

08.05.2025 23:47 โ€” ๐Ÿ‘ 1    ๐Ÿ” 0    ๐Ÿ’ฌ 1    ๐Ÿ“Œ 0

@cruzveralab is following 19 prominent accounts