Thank you to all authors involved in the project and to the NAR editorial team for the smooth publication process.
18.09.2025 08:40 — 👍 0 🔁 0 💬 0 📌 0
In this project, we profiled a site saturated library of BRCT variants for binding to ABRAXAS1 and CtIP (unfortunately, we could not include BRIP1 for technical reasons). This resulted in new knowledge on how these proteins interact and enabled us to develop mutations affecting single interactions.
18.09.2025 08:40 — 👍 1 🔁 0 💬 1 📌 0
Validate User
Happy to share our latest research on the BRCA1-BRCTs now online.
academic.oup.com/nar/article/...
Congrats to first author Venda for putting it all together! This project was a great collaboration with the @titiasixma.bsky.social lab who helped us give structural meaning to our observations.
18.09.2025 08:40 — 👍 19 🔁 6 💬 1 📌 1
In this project, we profiled a site saturated library of BRCT variants for binding to ABRAXAS1 and CtIP (unfortunately, we could not include BRIP1 for technical reasons). This resulted in new knowledge on how these proteins interact and enabled us to develop mutations affecting single interactions.
18.09.2025 08:35 — 👍 0 🔁 0 💬 0 📌 0
Woohoo! Congratulations AmelieFT@AFTLab and colleagues. Beautiful work, so happy for you.
14.08.2025 07:16 — 👍 0 🔁 0 💬 1 📌 0
a cartoon of a coyote with binoculars and the words looney tunes on the bottom right
ALT: a cartoon of a coyote with binoculars and the words looney tunes on the bottom right
We are looking for a candidate to apply to a #MSCA Postdoctoral Fellowship in our lab in the @CBM_CSIC_UAM, working on the connections between DNA replication dynamics, replication stress and genomic instability in cáncer. Contact us if you are interested and please retweet.
04.08.2025 13:32 — 👍 1 🔁 3 💬 0 📌 0
Congratulations, Emilio, Juan and both teams!
03.07.2025 13:05 — 👍 0 🔁 0 💬 0 📌 0
We’re kicking off our RepliFate introductions with @Phuc and her PI, @sylvie-noordermeer.bsky.social ! As part of the RepliFate network, they are contributing to exciting research in double-strand break (DSB) repair. Wanna know more about their work, hobbies, and fun facts? Check out their profiles!
25.02.2025 08:09 — 👍 6 🔁 3 💬 0 📌 0
Postdoc @altmeyerlab. Interested in Checkpoint maintenance, DNA replication, DNA repair & Imaging.
Group leader Divisions of Cancer Therapeutics and Breast Cancer Research | Deputy Director of the Centre for Target Validation | Institute of Cancer Research, London
Father of 2. Group Leader at CABIMER, Seville. Studying PTM signaling by MS-based proteomics in Genome biology.
1/2 PhD Fluid dynamics, PhD in Prado Lab, Postdoc in Vertegaal Lab.
https://www.cabimer.es/en/research-groups/genome-proteomics/
Senior editor @naturesmb.bsky.social. Views and opinions are personal.
Group leader at Institute of Molecular and Translational Medicine, UPOL
Former postdoc @barteklab.bsky.social.
My group explores DNA replication dynamics in response to PARP inhibitors.
We are based at the Epigenetics and Cell Fate Centre, at the University of Paris Cité, and we investigate chromatin dynamics during DNA damage repair.
https://epigenetics.u-paris.fr/
Professor studying DNA repair at the University of Pennsylvania School of Medicine
www.bernsteinlab.com
Chasing DNA double strand break repair outcomes and clastogen response
https://scholar.google.com/citations?user=JZpgwJwAAAAJ&hl=en
Cancer biologist, environment and cancer, guitarist, would-be evolutionary molecular biologist, bread baker, sometimes coder, amateur photographer, professional microscopist, & gardener. Lab site: https://blogs.dal.ca/dellairelab/
Scientist, Director of ISREC Foundation, mentor and manager, epigenetist
Molecular biologist. Group leader at MRC LMB Cambridge UK. Fellow at Clare Hall college. #CryoEM #RNAbiology #DNArepair
Views/opinions are my own.
https://www2.mrc-lmb.cam.ac.uk/group-leaders/n-to-s/lori-passmore/
Research on chromatin linked to gene regulation and genome stability. Big multisubunit complexes!
Quebec City, Canada
TheCoteLab.com
Professor and Director, Dept. of Biophysics & Biophysical Chemistry
Johns Hopkins School of Medicine, structural biologist, lover of chromatin and ubiquitin, fan of the active voice.
Scientist. https://www.sfeirlab.com/
Prof. at MSKCC and co-founder of Repare Therapeutics. 🇱🇧+🇺🇸 in NYC
PI @ Sloan Kettering Institute, New York | DNA replication | https://www.mskcc.org/research/ski/labs/dirk-remus | Co-Director, BCMB PhD program, Weill Cornell Medicine| https://gradschool.weill.cornell.edu/bcmb-allied-program | Views are my own.
