Jamie Hackett

🤩🤩 it’s been a while

New haircut 😁

Awhh, my lab are absolute legends!

... and it comes with a stipend!

We are looking to take on an intern at EMBL Rome, for anyone interested in CRISPR and Epigenetics training.

The traineeship is 3-12-months, in Rome (Italy), should start by July, and is supervised by the outstanding @steliostsagkris.bsky.social.

#job #internship; see info below...

Interested in doing a sabbatical at EMBL, at one of its 6 sites in Barcelona, Cambridge, Grenoble, Hamburg, Heidelberg or Rome?

Funding call with deadline 15 June, decisions in July.

www.embl.org/about/info/s...

This is great work Jake! the specificity of H3K4 editing in plants is very cool

Personally, I am partial to a microbe or two. But yes, focus would be on mammalian physiology

Absolutely

Group Leader - Molecular Mechanisms of Environmental Adaptation We are seeking to recruit a highly motivated scientist to establish and lead an independent research laboratory at the EMBL Epigenetics and Neurobiology Unit in Rome. EMBL provides a unique environmen...

Want to start an independent research group? ...with core funding, outstanding facilities & a curiosity-driven culture? Join us at @embl.org

We are recruiting across research themes, inc (epi)genomics, human dev bio, predictive modelling & neurobiology👇

embl.wd103.myworkdayjobs.com/en-US/EMBL/d...

Last day to apply for a postdoc in systems epigenomics in sunny Rome!

www.embl.org/jobs/positio...

Paternal microbiome perturbations impact offspring fitness Nature - Disturbances in the gut microbiota of male mice manifest as fitness defects in their offspring by affecting plancenta function, revealing a paternal gut–germline axis.

As an "EIPOD" interdisciplinary postdoc in @jamiehackett.bsky.social and our lab, @denbobalab.bsky.social found that "Paternal microbiome perturbations impact offspring fitness" (2024): antibiotic treatment of male mice led to low birth weight & higher mortality in offspring

www.nature.com/artic...

Strongly recommend DNAme researchers to take a look at this important study. Consistent with work from Schubeler lab: higher-order mut in DNAme reader proteins lead to only minor transcriptional changes. Reinforces the idea that DNAme does not establish heterochromatin through reader proteins

Please RS/RT. #GordonConference on "Histone and DNA Modifications" #epigenetics #chromatin 20-25. July 2025. Il Ciocco, Italy. Great speaker lineup.
➡️Register now www.grc.org/histone-and-...

Computational with a PhD in some quantiative science, and want to make the world a better place with AI in healthcare? Want to work with some of the most innovative AI groups in the life sciences? Want to work for Europe, across Cambridge and Heidelberg, living in the UK? Two more days to apply:

One of my illustrations made an appearance at the MPI #epigenetics conference! thanks to the boss @jamiehackett.bsky.social presenting the cool science we do in the lab 🔥

EMBL Jobs We offer a wide range of challenging scientific and non-scientific positions at all of our European locations and encourage applications from international candidates at all career levels.

Hi Kitty, just pointing out this independent position. Lots of other opportunities coming up at EMBL in Rome too.

www.embl.org/jobs/positio...

MRC four-year International PhD programme: Human Genetics, Genomics and Disease Applications now open.

Interested in an #interdisciplinary PhD on the #epigenetics of human disease (or know someone who is)? Come work with us through the 2025 MRC HGU PhD program. Excellent and friendly collegiate environment and a great city:
institute-genetics-cancer.ed.ac.uk/igc-graduate...

Please share 🙏 (1/2)

What a 1-2 last few days! Huge congrats Christa 👏

The good news: you only click on the "join" button once and then you following all the pack persists in the absence of the initiating stimulus. 😀
In all seriousness, a stellar group of folks to follow.

Protein-based inheritance could be the new frontier in understanding transgenerational epigenetic inheritance. Great preview from @odedrechavi.bsky.social and @ethanewe.bsky.social on a very interesting new paper from @wbderry.bsky.social lab.

We are beginning to understand how the full repertoire of inheritable units can affect phenotypic variability

Beyond the main player - DNA sequence - transmitted chromatin, RNA, metabolites and proteins all play their role…

By definition, enhancers can activate from a distance. But with increased distance between enhancer and promoter, the activation drops. To study this systematically, we build a synthetic locus: www.cell.com/molecular-ce... 1/12

Please check out this upcoming Gordon Conference (GRC) on Developmental Biology - March 2025

Very diverse and relevant topics! and Gordon Research Seminar (GRS) accompanying it as well ! (speaker list in commentts)
www.grc.org/developmenta...

Almost 1 month left to submit your abstract for the #Epigenetics2025 conference, organized by @gensocuk.bsky.social
We’ve put together a fantastic scientific program, and Northern Ireland is a wonderful destination to explore.

Advert detailing a postdoctoral scientist position at EMBL Rome. Contact: jamie.hackett@embl.it

Postdoc positions in epigenetics!

We have several opportunities to investigate big picture questions on (epi)genome function & mechanisms

Based @embl.org near Rome (Italy), we offer full scientific support/facilities, training & funding. Also...☀️🏛️🍕🏖️

See👇or contact me for other options. Pls RS

Many other super lab members not (yet) on Bluesky! So finally, two postdocs that just moved on...

@denbobalab.bsky.social has established his group at MPI on #microbiome-germline axis. @mdura.bsky.social has just preprinted on #intergenerational-inheritance and is on the market!

Check them out!

Sex chromosomes shape the transcriptional landscape of the preimplantation mouse embryo Sex chromosomes are emerging as key regulators of adult health and disease in males (XY) and females (XX), but their impact on embryo development is poorly understood. Using single-cell RNA sequencing...

Looks like a really interesting preprint from James Turner’s lab (who needs to migrate over here!) www.biorxiv.org/content/10.1...

Don’t miss @steliostsagkris.bsky.social for infinite technical knowledge of CRISPR perturbation screening!
Stelios is also the lab gastruloid guru 🧫

Always has interesting and constructive takes on papers so keep an eye on this one!

Fearless grad student @catrinteleri.bsky.social leads a major computational analysis project. Want to discuss polycomb function, ask Catrin!

More of a silent scroller than prolific poster, if we all follow Catrin - apart from being quite funny - we’ll hear more of her insights!