Dillingham Lab

Bacteriocin biophysics: From protein-protein interaction models to navigators of the bacterial cell envelope Bacteriocins are toxins deployed by bacteria to kill their competitors. Here, I reflect on my laboratory’s work on protein bacteriocins and their immunity proteins from Gram-negative bacteria. We unco...

A gift of an article from the inimitable Colin Kleanthous as he says a moving farewell to his laboratory. A brave, unrepentant and scientifically brilliant journey is described - please have a read, friends.

www.jbc.org/article/S002...

Are you ready for 2026? Social DNAing is! See who is coming. Sign up at www.cancer.columbia.edu/research/pro...

Exploiting the bacterial DNA damage response as an alternative antimicrobial at Newcastle University on FindAPhD.com PhD Project - Exploiting the bacterial DNA damage response as an alternative antimicrobial at Newcastle University, listed on FindAPhD.com

E. coli is the leading bacterium causing death from AMR infections worldwide. If you'd like to explore approaches to exploit the DNA damage response as alternative antimicrobial, please apply to the following PhD studentship available in my lab starting October 2026: www.findaphd.com/phds/project...

Totally! 💯
Whenever there is a survey here in the UK, I keep suggesting that every grant holder should review 4 grant proposals per year for the body from which they receive funding. This should be a commitment at the stage of accepting the award.
If you have received,you give back to the community

Alessandro Costa @costalaboratory.bsky.social, Dana Branzei and myself are co-organising the 2026 Machines on Genes meeting in beautiful Crete as the 94th Harden Conference hosted by @biochemsoc.bsky.social

Register now - lots of opportunities for selected talks www.eventsforce.net/biochemsoc/f...

We are recruiting a postdoctoral fellow to study mechanisms of DNA replication stress using single-molecule imaging tools. If you are excited about microscopy, replisome dynamics, and genome stability, we’d love to hear from you.

Application deadline: 24 December

www.crick.ac.uk/careers-stud...

🔬 Interested in bacterial immune systems & AMR, or how antibiotics affect phage infectivity?

Three SWBio DTP PhD project opportunities linked to the MultiDefence consortium are now open (1/4)

#PhD #DoctoralTraining #ResearchCarrers #LifeSciences #phagesky #AMR #microsky #PhDPositions

34 fully-funded PhD studentships in the Biosciences across UK Universities in the South West (including Bristol Biochemistry!)

Home and International students eligible

Information and applications here
www.swbio.ac.uk

Join the LMB's PhD programme! Applications now open for October 2026 Deadline 2nd December 2025

Considering the LMB for your PhD?
We’ve got over 25 projects available, covering a wide array of topics. Check them out here: www2.mrc-lmb.cam.ac.uk/students/int...
Apply by 2nd DEC for Autumn 2026 admission.

Biomolecular Science Fellowship Day - St Andrews, Fife (GB) job with UNIVERSITY OF ST ANDREWS | 12848597 The School of Biology at the University of St Andrews is inviting applications from outstanding visionary Research Fellow and Future Leader candida...

Thinking about your first steps to independent research? We'd love to hear from you. More details below, or contact me directly for details - reposts appreciated!

www.nature.com/naturecareer...

Archaeal cells whose DNA has been stained with a blue dye. Zoomed-in images of mutant cells that display chromosome segregation defects.

High-resolution images of DNA-protein complexes obtained with atomic force microscopy. Upon binding, the protein bridges distant sites, forming loops.

📢 Interested in #chromosomes 🧬 & #archaea thriving at the edge of life? PhD project in York,UK on how archaea pass on their genome to daughter cells.Friendly supervisors: me, @steve-quinn-lab.bsky.social & @georgerheath.bsky.social

www.findaphd.com/phds/project...
📅 January 7, 2026
Please RP🙏thx!

DNA REPAIR/GENOME STABILITY CONFERENCES

🧬 List of 2026 DNA repair and genome stability conferences, now updated. Please let me know if there is anything missing!
docs.google.com/spreadsheets...

Exciting PhD opportunity! Uncover the molecular mechanism of the MADS bacterial immune system and its synergy with CRISPR-Cas. Based in the Szczelkun lab in Bristol with strong collaboration with the Blower lab at NEB and opportunities to work with other amazing research groups! Link below:

Please RT. Post-doc opportunity alert! 💥 closing 10th December.. Come join our team (www.thelowlab.org) at Imperial, London, working on the structure and mechanism of bacterial secretion systems.

For more details and to apply please see

www.imperial.ac.uk/jobs/search-...

Rotation biology PhDs | John Innes Centre Prestigious studentships, for entry in October 2022, this multi-disciplinary PhD programme includes; plant science, microbiology, biological chemistry, applied mathematics…

Applications are now OPEN for the JIF Rotation PhD Programme

This prestigious 4-year #PhD programme trains graduate students in Plant and Microbial Sciences at the JIC, @thesainsburylab.bsky.social and @earlhaminst.bsky.social.

🗓️ Closing date - 13 November 2025

www.jic.ac.uk/training-car...

Please join us in the North East on the 5th of November as we celebrate with a one day symposium for the launch of our BBSRC funded 100 keV Tundra TEM aka the Northern Eye:
nusbf.ncl.ac.uk/ccpem-tfs-ne...
The symposium has been kindly sponsored by
@thermofishersci.bsky.social & @ccpem.bsky.social

I’m really excited to share that I’ve been awarded a Wellcome Trust Career Development Award to start my own research group at Oxford University Biochemistry Department @BiochemOxford 🧬🎉

Funded PhD: Understanding the role of the ribosomal P-stalk in immune responses at University of Bristol on FindAPhD.com PhD Project - Funded PhD: Understanding the role of the ribosomal P-stalk in immune responses at University of Bristol, listed on FindAPhD.com

First ad for a position in my new lab at the University of Bristol! If you are looking for a fully funded PhD in cutting edge science that will be based in a supportive environment, and in a great city, check out the link below!

www.findaphd.com/phds/project...

How do SMC complexes load onto DNA to get ready for loop extrusion?

@roisnehamelinf.bsky.social & co discovered that Wadjet, an SMC complex involved in bacterial DNA immunity, performs some impressive molecular gymnastics 🤸‍♂️🤸‍♂️🤸‍♂️.

Check out the new paper: www.cell.com/molecular-ce...

Independent research fellowships leading to tenured positions at the John Innes Centre.

Repost = nice. Thank you very much!!!

PhD student recruitment PhD recruitment information.

2026 PhD recruitment is now open.

As well as our main PhD recruitment, which is open to all, we are pleased to be offering scholarships for candidates of Black or mixed Black heritage. Learn more and apply on our website:

www.crick.ac.uk/careers-stud...

grainger birmingham PhD Projects, Programmes & Scholarships - 3 PhDs Listed FindAPhD. Search Funded PhD Projects, Programmes & Scholarships in grainger birmingham. Search for PhD funding, scholarships & studentships in the UK, Europe and around the world.

Our lab is offering 3 PhD projects this year across 3 different topics: antibiotic resistance mechanisms, evolution of pathogenic bacteria, and fundamental mechanisms of gene regulation.

www.findaphd.com/phds/?Keywor...

Still a couple of days left to apply for this postdoc #job. With access to world-class facilities, you will unravel the DNA-packaging mechanisms used by #phages and the unusual #GeneTransferAgents, and explore the impact of these tiny machines on evolution, resistance, and biotech. @ukri.org #bbsrc

Great to be there and thanks for having me!

Please RT 🙏 If you’re an early career researcher working in the fields of structural or synthetic biology wishing to start your lab then come join us at Imperial. We’re looking to support outstanding individuals for external Career Development Awards/Fellowships.

www.imperial.ac.uk/media/imperi...

Please RT! Call for Fellows! If you’re a structural biologist and wanting to start your lab by applying for an external Fellowship then we at Imperial may be excited to host you. Synthetic biologists too.. Please submit expression of interest with details below 🙏

www.imperial.ac.uk/media/imperi...

Sussex is the host for this year's South West Structural Biology Consortium meeting [we snuck in... !]. Looking forward to hearing talks from Universities of Bath, Bristol, Cardiff, Exeter, Portsmouth, Southampton and of course, Sussex!

AlphaFold - A practical guide AlphaFold - A practical guide

Recently I learnt that EMBL-EBI has a free online course about AlphaFold — how it works, strengths and limitations, how to use it — and it's very good!

There are also little quizzes and interactives.
www.ebi.ac.uk/training/onl...

Postdoctoral Fellow - Costa Lab Salary for this Role: From £45,500 with benefits, subject to skills and experience. Job Title: Postdoctoral Fellow - Costa Lab Reports to: Alessandro Costa Closing Date: 03/Aug/2025 23.59 GMT Job Desc...

Less than two weeks left to apply!

Postdoc positions in my lab to study

1. initiation of DNA replication.

2. chromatin replication/epigenetic inheritance.

Great for biochemists, biophysicists & structural biologists.

Deadline 3 August 2025.

crick.wd3.myworkdayjobs.com/External/job...

PDB101: Molecule of the Month: Fifty Years of Open Access to PDB Structures The Protein Data Bank is celebrating its golden anniversary!

Interested in the "Crystallography Through The Decades" session at #aca2025?
Take a tour of the PDB over the years at PDB-101
pdb101.rcsb.org/motm...