DanioKrish

YouTube video by John Rawls Zebrafish in the wild

Part 6: For decades, the zebrafish has helped scientists unlock the mysteries of genetics, development, & disease. But the fish that power most discoveries have spent generations inside lab tanks. This video captures footage of zebrafish in their natural environment in Nepal.
youtu.be/cCZhZpPALqw

CRISPR-based functional genomics tools in vertebrate models - Experimental & Molecular Medicine Recent advances in DNA sequencing have allowed scientists to gather vast amounts of genetic data, but understanding what those sequences actually do requires additional tools that allow scientists to ...

Wrote a big review with my friend and colleague @varshneylab.social on the state-of-the-art in CRISPR used experimentally in vivo. We wanted to focus on their use in experimental vertebrate animals (apparently passé now but we persist).

I’m open to postdoctoral positions and collaborative projects, and excited to learn new techniques and contribute meaningfully to the field.
Please feel free to reach out or connect!
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I am a recipient of the DST-INSPIRE Fellowship and have received several best presentation awards at national and international conferences. I also had the privilege of presenting my work at the 18th International Zebrafish Conference in Kyoto, Japan last year.
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💻 Computational biology – Applied homology modeling, molecular docking, and MD simulations to support mechanistic insights .
🧠 Neurotoxicity models – Worked on zebrafish-based models of Parkinson’s disease and nanoparticle-mediated therapeutic interventions.
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🧪 Behavioral and ototoxicity assays – Designed and optimized custom rheotaxis assays to assess functional impairment following toxicant exposure; with DASPEI staining and SEM-based ultrastructural analysis to evaluate neuromast integrity.
🧫 Molecular biology – Skilled in RT-qPCR and genotyping.
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In my PhD, I have acquired following research skills
🔬 CRISPR/Cas9 mutagenesis – Developed and characterized zebrafish tubulin mutants to study microtubule function.
🧬 Tol2 transgenesis – Established stable transgenic lines for in vivo tracking of neuronal progenitor dynamics.

Hello Zebrafish Community,
I am currently exploring new opportunities in neurobiology and developmental genetics, with over 5 years of research experience using zebrafish as a model system.
#OpentoWork #Postdoc #Zebrafish #Neurobiology #DevelopmentalGenetics #ZebrafishCareers
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A man with a black hat and sunglasses 😎