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Esther Uijttewaal

@euijttewaal.bsky.social

36 Followers  |  23 Following  |  1 Posts  |  Joined: 16.12.2024  |  1.6459

Latest posts by euijttewaal.bsky.social on Bluesky

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CRISPR-StAR enables high-resolution genetic screening in complex in vivo models - Nature Biotechnology Pooled genetic CRISPR screening is improved in complex models through leveraging internal controls.

My PhD work is published! 🌟 We developed CRISPR-StAR, a new genetic screening method that uses internal controls that face the same challenges as edited cells—making the results more robust. In therapy-resistant melanoma, we revealed differential genetic dependencies in vitro and in vivo. Curious?

18.12.2024 15:10 — 👍 7    🔁 2    💬 0    📌 0
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CRISPR-StAR enables high-resolution genetic screening in complex in vivo models - Nature Biotechnology Pooled genetic CRISPR screening is improved in complex models through leveraging internal controls.

Today we published a new paradigm to do CRISPR screens in complex model systems such as in vivo but also e.g. in organoids. The publication came out in Nature Biotechnology.
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www.nature.com/articles/s41...

16.12.2024 12:02 — 👍 48    🔁 17    💬 2    📌 3

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